The study deals with characterization of microorganism's dynamic growth in different relative humidity such as Bacillus subtilis, Micrococcus flavus, Staphylococcus aureus, Escherichia coli in fiber filters media used In air purifications systems. Viability of airborne microorganisms was different depending on RH condition. Highest viability, even when RH value was 20%, characterized Bacillus subtilis - spore forming bacteria. Low survival was indicated by bacteria Escherichia coli and Staphylococcus aureus.
A series of fourteen derivatives of adamantane was synthesised. The new compound 4-(adamant-1-ylmethoxycarbonyl)phthalanhydride obtained from 1-adamantane- methanol and trimellitic anhydride chloride appeared very useful for preparation of a number of N-substituted phthalimides. Antimicrobial activity of the newly obtained derivatives such as, for example, 4-(adamant-1-ylmethoxycarbonyl)-N-(5-carboxypentamethylene)phthalimide or 4-(adamant-1-ylmethoxycarbonyl)-N-(L-alanyl)phthalimide was tested against Staphylococcus aureus, Bacillus sp., Micrococcus flavus and Enterococcus faecium. The minimal inhibitory concentration (MIC) for these compounds against S. aureus were 0.022 and 0.05 µg/ml, respectively.
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