The article examines the features of the formation of an integrated system for managing sustainable development of the region. Considered scientific approaches to develop a structure and mechanism of an integrated system of regional development, including through the establishment of institutional mechanisms for the sustainable development. The principles of sustainability of natural systems and human indicators characterizing the processes of development of the individual subsystems: social, economic and environmental are considered. The functions, distinctive characteristics and prospects of integrated management system implementation in practice of management at the regional level. Highlighted the major problems of transition to sustainable development of the regions of Ukraine and Belarus. The characteristics of integrated strategies for sustainable development, as well as key features that it provides. The organizational and managerial conditions of transformation of regional systems for sustainable development are analysed.
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