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Chromosomal localization of 13 candidate genes for human obesity in the pig genome

100%

Nowacka-Woszuk J. , Szczerbal I. , Fijak-Nowak H. , Switonski M.

Journal of Applied Genetics

2008

tom 49

nr 4

373-377

Thirteen candidate genes for human obesity were selected for cytogenetic mapping by FISH in the pig genome. Among them, 6 genes were assigned to chromosomes for the first time (NR3C1, GNB3, ADRB1, ADRB2, ADRB3 and UCP1). Location of the other 7 genes (INSIG2, LIPIN1, PLIN, NAMPT, ADIPOQ, UCP2 and UCP3), earlier mapped by somatic cell hybridization or with the use of a radiation hybrid panel, was verified (INSIG2) or more precisely described. The genes were assigned to the following chromosomes: INSIG2 to SSC15q12, LIPIN1 to SSC3q26, NR3C1 to SSC2q29, PLIN to SSC7q15, GNB3 to SSC5q21, NAMPT to SSC9q23, ADIPOQ to SSC13q41, ADRB1 to SSC14q28, ADRB2 to SSC2q29, ADRB3 to SSC15q13-14, UCP1 to SSC8q21-22, and both UCP2 and UCP3 to SSC9p24. Most of the genes were located within known QTL for pig fatness traits.

BIOSOCIALITA: SOCIÁLNE DÔSLEDKY BIOVEDECKÉHO POZNANIA

86%

Tomašovičová J.

Filozofia (Philosophy)

2015

tom 70

nr 5

356 – 366

Due to recent researches in modern genetics and their practical applications, we are witnesses to the change of contemporary society as well as its social and political mechanisms. The article focuses on Rabinow’s concept of bio-sociality as a new form of communality and creating identity. Nowadays neither ethical patterns nor social mechanisms are as well-grounded as they used to be. This new bio-sociality is intended to oppose the familiar socio-biology. First, the potential analytical power of the concept of bio-sociality is under discussion followed by the determination of the aspects not taken into account by Rabinow. Second, the paper tries to answer a wider question of whether the linkage between some contemporary political power practices and the eugenic strategies of the past does not contradict the very new vision of bio-sociality proposed by Rabinow.