The application of high pressure for biological macromolecules investigations was an object of interest already in the begining of this century.Recently, attention has been paid to this method because of its possible applications in biotechnology.In this paper, we summarized the data existing in the literature on the machanism of high pressure effects on protein and nucleic acids.We also reviewed various practical aplications of high pressure, especially in food industry.
For the first time, high pressure was used for milk sterilization at the beginning of this century. However, only recently attention has been paid to this method and its possible applications in food preservation and inactivation of some viruses. In this review, we summarize high pressure effects on biological macromolecules such as proteins, nucleic acids, ribosomes and other cell components. We also show examples of practical application of high pressure in food conservation and medicine.
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