In the article the economic estimation of ecological losses from production in regions of Ukraine in 2001-2009 is carried out. The expediency of regional economy ecoefficiency increase on the basis of research of tendencies of gross regional product’s (GRP) ecological capacity and its components is proved. The share of annual GRP increment of Ukrainian regions which should be provided by the resource saving and dematerialization intensification in order to achieve the sustainable development goals is defined.
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