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The Effect of Cholesterol and 7-Dechydrocholesterol on Lipid Bilayers. Ultrasound Study

100%

Wójtowicz K. , Gawda H.

2004

tom Vol. 25

243-248

In the study effect on phosphocholine bilayers of cholesterol additive and of 7-DHC additive was compared depending on the lenght of phosphocholine acyl chain. Ultrasound absorption measurements were the basis of invastigations. They have shown that structurally similar cholesterol and 7-DHC molecue, by being more flat and elastic than a cholesterol molecule, more strongly binds with lipid molecules.

The in vitro interaction of C 27-sterols with the erythrocyte membranes depends on the sterol structure and concentration

51%

Tuganova A. V. , Kotsyuruba A. V.

Cellular and Molecular Biology Letters

1996

tom 01

nr 2

We tested in vitro the role of functional groups and overall structure of sterol skeleton as well as sterol concentration in the ability of erythrocyte membranes to accumulate C27-sterol molecules. It is established that association with erythrocyte membranes of C27-sterols: cholesterol, 7-dehydrocholesterol, cholecalciferol (vitamin D3), calcitriol (lα,25-dihydroxycholecalciferol), ecdysterone (20-hydroxyecdysone) and 2-desoxyecdysterone depends on sterols concentrations and structure.