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Zmiany we właściwościach kolagenu skór świńskich wskutek wapnienia (Referat na XIX Kongresie IULTCS w Melbourne)

100%

Takahashi K. , Shirai K. , Wada K.

tom 43

nr 07

Single-hole one-electron superexcited states and doubly-excited states of molecules as studied by coincident electron-energy-loss spectroscopy

88%

Odagiri T. , Fukuzawa H. , Takahashi K. , Kouchi N. , Hatano Y.

tom Vol. 48, nr 2

95-102

The single-hole one-electron superexcited states and doubly-excited states of H2, D2, N2 and O2 have been investigated by means of the coincident electron-energy-loss spectroscopy that we developed. In this method the electron-energy-loss spectra tagged with the vacuum ultraviolet fluorescences emitted by the neutral fragments produced from superexcited molecules are measured by means of electron-photon coincidence technique. The contribution from ionization in this sort of electronenergy- loss spectra is suppressed to a large extent, and thus the structures attributed to the superexcited states of molecules become highlighted. The comparison with the photoexcitation experiments by means of the oscillator strengths give us clear discrimination between allowed and forbidden superexcited-states. As to H2, D2, and N2, the doubly-excited states including those found in the present experiment have been investigated in terms of both their energies and dynamical behavior. A new possibility of the coincident electron-energy-loss spectroscopy has been established in investigating the single-hole one-electron superexcited states of O2: the time-resolved coincident electron-energy-loss spectrum has been measured to distinguish between the direct process producing excited oxygen atoms and indirect one due to cascade transition. It has turned out that the coincident electron-energy-loss spectroscopy is a key tool for investigating superexcited molecules.

Effect of ruminal and duodenal infusion of starch and protein on GH secretion in sheep

63%

Hagino A. , Takahashi K. , Matsuda A. , Kawai M. , Ohtomo Y. , Oda S. , Sasaki Y. , Katoh K. , Obara Y.

tom 13

nr 1

Transplantation of human bone marrow stromal cell-derived neuroregenrative cells promotes functional recovery after spinal cord injury in mice

63%

Mannoji C. , Koda M. , Kamiya K. , Dezawa M. , Hashimoto M. , Furuya T. , Okawa A. , Takahashi K. , Yamazaki M.

nr 4

Transplantation of bone marrow stromal cells (BMSCs) for spinal cord injury (SCI) has been shown to improve functional outcome. BMSCs can be easily obtained from bone marrow aspirate and have fewer problems in the clinical application for human SCI from the ethical and legal points of view. Recently, we produced cells with neural stem and/or progenitor cell property and neural regeneration supporting capacity from human bone marrow stromal cells (human bone marrow stromal cell-derived neuroregenerative cells: hBMSC-NRs). The aim of the present study was to clarify the effectiveness of transplantation of hBMSC-NRs to injured spinal cord of severe combined immunodeficiency (NOD/SCID) mice. Neurite outgrowth assay of PC-12 cells was performed. One week after a T9-level contusion SCI, hBMSCs or hBMSC-NRs were transplanted into the spinal cord. After the transplantation, functional and histological examinations were performed. Conditioned media of hBMSC-NRs significantly promoted the neurite outgrowth of PC-12 cells in vitro. Transplanted hBMSC-NRs survived in the injured spinal cord 8 weeks after SCI. Immunohistochemistry revealed that the density of serotonin-positive fibers of the transplanted group was significantly higher than that of the control group at the epicenter and caudal segment to the injured site. The recovery of hind limb function of the hBMSC-NRs group was significantly better than that of the control group. In conclusion, hBMSC-NRs can be one of the realistic candidates for cell transplantation therapy for human SCI.