Wyniki wyszukiwania - Biblioteka Nauki

1

Amygdaloid complex of the dog

100%

Maksymowicz K.

Acta Biologiae Experimentalis

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1963

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tom 23

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nr 2

2

A three-dimensional model of the striatal nuclei in the dog's brain

63%

Kreiner J. , Maksymowicz K.

Acta Biologiae Experimentalis

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1962

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tom 22

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nr 1

3

Skanowanie 3D jako metoda obrazowania złożonych i rozległych relacji przestrzennych dla potrzeb medycyny sądowej i kryminalistyki - ocena przydatności

51%

Maksymowicz K. , Kobielarz M. , Jurek T.

Wiadomości Konserwatorskie

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2009

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tom Nr 26

689-695

PL

Oparta na skanerze laserowym 3D metoda dokumentacji otworzyła nowe horyzonty dla medycyny sądowej i kryminalistyki, głównie ze względu na jej zdolność faktycznie 'zamrożenia' jakiegokolwiek miejsca przestępstwa. Niektóre cechy, takie jak wysoka rozdzielczość zapisywania danych tworzących obraz, zachowując badany przedmiot w stanie nietkniętym, szybkość gromadzenia danych, możliwość bieżącego zapisu danych w postaci pliku i przesyłania ich na dowolną odległość, niski koszt pojedynczych oględzin, prostota konserwacji skanera, jego mobilność, niezależność od zewnętrznych źródeł energii, możliwości kooperacji z każdym rodzajem narzędzia badawczego operującego w technice cyfrowej, stawiają skaner 3D w roli przydatnego i wszechstronnego narzędzia w codziennej praktyce medycyny sądowej i kryminalistyki.

EN

Based on 3D laser scanner method of documentation has opened new prospects for forensic medicine and crime detection, mainly in respect to its ability to virtually efreezei any crime scene. Some features like high resolution of the imaging data recording, preserving the examined object in intact state, speed of data collection, possibility of instant data filing and transmission at any distance, low cost of singular examination, simplicity of scanner maintenance, its mobility, independence from an external source of energy, possibility of cooperation with every kind of research tool working in digital technique, put the 3D scanner as a useful and versatile tool in everyday forensic medicine and crime detection practice.

4

Topographic and macroscopic characteristics of liver in red-eared turtle (Trachemys scripta elegans) after hibernation. Part I

51%

Marycz K. , Kleckowska-Nawrot J. , Maksymowicz K. , Wojciechowicz E.

Electronic Journal of Polish Agricultural Universities. Series Veterinary Medicine

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2009

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tom 12

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nr 2

5

Elastin and collagen fibres alterations for abdominal aortic aneurysms population with constant maximum diameter size

51%

Kobielarz M. , Maksymowicz K. , Będziński R.

Engineering of Biomaterials

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2011

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tom Vol. 14, no. 102

2--6

EN

Development of abdominal aortic aneurysm (AAA) is a dynamic process proceeding as a result of the multi-factor pathological remodelling of elastin and collagen fibres, results an aneurysm expansion. In clinical practice, development of AAA is identified with aneurysm growth. Hence, the aim of this paper is to propose a taxonomy of load-bearing structural components alterations for AAA with relatively constant maximum diameter (average diameter 6.9±0.8 cm). Structural investigations of normal (n=47) and aneurismal (n=46) vessels were carried out on the basis of histological and ultrastructural examinations. The histological preparations were subjected to histometric evaluation; the number of collagen and elastin fibres and additionally the thickness of the particular vascular wall layers. A qualitative analysis of the abdominal aortic wall, mainly estimation of fibres arrangement, based on histological and ultrastructural (SEM) examinations were additionally performed. Using a cluster analysis, three stages of load-bearing fibres alterations for AAA population were distinguished. The clusters were systematized according to NAA results. For AAA population with relatively constant maximum diameter in the first stage of load-bearing fibres remodeling was observed a substantial loss of elastin fibres. The second stage is characterized by an increase in the number of collagen fibres. In the final stage the number of collagen is dramatically reduced. Presented results provide evidence to risk of AAA rupture is not connected with AAA size but a remodelling of extra-cellular matrix proteins. The remodelling is accompanied by changes in the AAA wall thickness, which should be taken into consideration when evaluating the degree of advancement of this disease.

6

Histological and ultrastructural changes of the tongue in red-eared turtle (Trachemys scripta elegans) after hibernation

51%

Marycz K. , Kleckowska-Nawrot J. , Maksymowicz K. , Kalinski K.

Electronic Journal of Polish Agricultural Universities. Series Veterinary Medicine

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2009

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tom 12

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nr 2

7

Influence of selective digestion of elastin and collagen on mechanical properties of human aortas

45%

Kobielarz M. , Chwiłkowska A. , Turek A. , Maksymowicz K. , Marciniak M.

Acta of Bioengineering and Biomechanics

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2015

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tom Vol. 17, no. 2

55--62

EN

Purpose: There are two families of fibres taking part in the process of mechanical loads transfer, i.e. elastin and collagen fibres. Their number, spatial arrangement and specific properties determine the capacity of a blood vessels to resist mechanical loads resulting from the impact of blood on vessel walls. The purpose of the present paper is to define the load-bearing capacities of elastin and collagen scaffolds equivalent to natural fibre arrangements of human aorta and produced by selective digestion. Methods: Samples of thoracic human aortas were digested by using phosphate buffer of trypsin at pH 8.0 for 22 hours in order to degrade elastin and by autoclaving followed by incubation in 90% formic acid for 22 hours. The efficacy of digestion was assessed immunohistochemically. Mechanical properties of pre-stretched native and digested samples were determined by uniaxial tensile test. Results: Samples subjected to autoclaving have been successfully deprived of both types of collagen and elastin has been intact. Treatment with trypsin caused a removal of elastin and the presence of type I and IV collagen was demonstrated. Digestion of aortic samples either by formic acid or trypsin has resulted significantly decreasing mechanical properties in comparison with native samples. Conclusions: Collagen and elastin scaffold-like stuctures have been effectively produced by selective digestion of thoracic human aorta and their contribution to the load-bearing process was evaluated. Isolated collagen network are more durable and stiffer and less deformable than elastin network, hence are responsible for load-bearing process at higher strain since the range of working of elastin is at lower strain values.

8

Zmienność cech plonotwórczych gryki odmiany Kora i form Red corolla i Samokończąca

45%

Wolinska J. , Wolinski J. , Wyrzykowska M. , Zieminska J. , Maksymowicz K.

Annales Universitatis Mariae Curie-Skłodowska. Sectio E. Agricultura

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2015

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tom 70

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nr 1

9

Lethal accidents in storage equipment: a report of two cases

45%

Jurek T. , Szleszkowski L. , Maksymowicz K. , Wachel K. , Drozd R.

Annals of Agricultural and Environmental Medicine

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2009

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tom 16

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nr 1

169-172

10

Ocena histologiczna i ultrastrukturalna ścian tętniaków aorty brzusznej

38%

Kobielarz M. , Maksymowicz K. , Kaleta K. , Kuropka P. , Marycz K. , Będziński R.

Engineering of Biomaterials

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2010

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tom Vol. 13, no. 99-101

83--87

PL

Rozwój tętniaków, w tym aorty brzusznej (AAA) jest dynamicznym procesem, który zachodzi w wyniku wieloczynnikowego, patologicznego remodelingu tkanki łącznej ściany aorty. Badania strukturalne ścian naczyń tętniczych (zdrowych i z tętniakiem) przeprowadzono w oparciu o analizę histologiczną i ultrastrukturalną. Analiza porównawcza wyników wykazała, że w przypadku preparatów ścian tętniaków aorty brzusznej odnotowano cały szereg zmian, które są charakterystyczne dla rozważanego schorzenia, w tym: wzmożony proces neowaskularyzacji oraz obecność nacieku zapalnego. Ponadto, odnotowano zatarcie granic między warstwami oraz redukcję ich grubości, co szczególnie zaznaczyło się w przypadku błony wewnętrznej. Zaobserwowano istotny ubytek włókien elastynowych oraz zmienny co do intensywności w poszczególnych przypadkach ubytek włókien kolagenowych. Wykazano także, że zmiany w liczbie włókien tkanki łącznej odgrywają kluczową rolę w procesie rozwoju AAA.

EN

The development of abdominal aortic aneurysm (AAA) is a dynamic process proceeding as a result of the multi-factor pathological remodelling of the connective tissue. Structural investigations of normal and aneurismal vessels were carried out on the basis of histological and ultrastructural examinations. A comparative analysis of the experimental results revealed a whole series of changes characteristic of the AAA walls (intensified neovascularisation and inflammatory infiltrations). In addition, the boundaries between the layers were found to be blurred and the thickness of the layers was reduced. A substantial loss of elastin fibres and a case-specific loss of collagen fibres were observed. The number of connective tissue fibres play a key role in the AAA development.

11

Relationship between calcification, atherosclerosis and matrix proteins in the human aorta

38%

Kuzan A. , Wisniewski J. , Maksymowicz K. , Kobielarz M. , Gamian A. , Chwilkowska A.

Folia Histochemica et Cytobiologica

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2021

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tom 59

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nr 1

12

Chemical composition of human and canine facia lata

38%

Maksymowicz K. , Marycz K. , Szotek S. , Kalinski K. , Serwa E. , Lukomski R. , Czogala J.

Acta Biochimica Polonica

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2012

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tom 59

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nr 4

EN

The fascial system is an integral part of the musculoskeletal system. It is a three-dimensional network of connective tissue spreading ubiquitously throughout the body, surrounding muscles, bones, internal organs, nerves, vessels, and other structures. The basic biophysical properties of the fascial system are determined by its structure and chemical composition. This study aimed to determine the elemental composition of pathologically unchanged fascia lata of the thigh, collected during autopsies on humans and dogs. The wide spectrum of elements analysed included both macro and micro elements. The analyses were conducted using scanning electron microscopy with X-ray microanalysis (SEM-EDS). Concentrations of the following macro and micro elements were dermined: C, N, O, Na, Mg, Al, Si, P, S, Cl, K, Ca, Ti, Fe Co, Ni, Cu, and Zn. The obtained results showed significant differences between human and canine fascia lata regarding the content of most of the examined elements (p < 0.05), except for N. These data may in future provide a starting point for the establishment of reference values for the content of various elements in normal fascial tissue and may also serve to verify the usefulness of experimental animal material as a substitute for human tissue.

13

The intima with early atherosclerotic lesions is load-bearing component of human thoracic aorta

38%

Kobielarz M. , Kozuń M. , Kuzan A. , Maksymowicz K. , Witkiewicz W. , Pezowicz C.

Biocybernetics and Biomedical Engineering

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2017

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tom Vol. 37, no. 1

35--43

EN

The aim of the study was to evaluate the mechanical properties of the adventitia, media, and especially intima of the human thoracic aortic wall in the early stages of atherosclerosis (stage I to III according to the Stary's classification). Histological and immunohistochemical techniques were used to evaluate the severity of atherosclerosis and the correctness of separation of the respective layers. Circumferential specimens of the adventitia, media, and intima (n = 193) were prepared from 27 arteries. The mechanical properties, i.e. the ultimate tensile strength, the maximum strain, and the maximum tangential elastic moduli, were determined in uniaxial tensile test and presented as a median (Me). The tensile strength of the intima (Me = 105 kPa) is comparable to the media (Me = 123 kPa) and lower than for the adventitia (Me = 808.5 kPa). The intima also undergoes the lowest maximum strain (Me = 0.008), and its elastic modulus (Me = 11510 kPa) is significantly higher compared to the media (Me = 5280 kPa). Therefore, presented results indicate that even in the early stages of atherosclerotic development the intima takes part in the process of mechanical loads bearing.

14

Właściwości skóry ludzkiej uzyskane w testach mechanicznych i techniką spektroskopii Ramana

32%

Szotek S. , Będziński R. , Kobielarz M. , Gąsior-Głogowska M. , Komorowska M. , Maksymowicz K. , Hanuza J. , Hermanowicz K.

Engineering of Biomaterials

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2009

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tom Vol. 12, no. 89-91

207--209

PL

Celem przeprowadzonych badań było porównanie charakterystyk otrzymanych: w testach wytrzymałościowych i z pomiarów spektroskopowych. W pracy wyznaczono podstawowe parametry mechaniczne skóry, które są zdeterminowane ułożeniem włókien kolagenowych. Następnie zarejestrowano widma ramanowskie badanej tkanki, zidentyfikowano pasma charakterystyczne dla białka kolagenowego. Na podstawie analizy uzyskanych wyników, dla kolejnych etapów rozciągnięcia skóry, zaobserwowano między innymi różnice w położeniu maksimum pasma amidu I (1658cm-1) w zależności od kierunku rozciągania próbki. Porównanie, w obu metodach charakterystycznych zakresów, zachodzących zmian wykazało możliwość stosowania Spektroskopii Ramana w celu wyznaczenia kierunku ułożenia włókien kolagenowych w trakcie rozciągania co jest istotne z punktu widzenia przeszczepów skóry.

EN

The aim of the investigations was to compare the characteristics obtained from strength tests and spectroscopic measurements. The basic skin parameters dependent on the arrangement of collagen fibres were determined. Then Raman spectra of the investigated tissue were recorded and bands characteristic of collagen protein were identified. An analysis of the results for the successive stages of skin stretching showed, among other things, differences in the location of the amid I band maximum (1658cm-1) depending on the direction of specimen stretching. A comparison of the characteristic ranges of change determined by the two methods showed that Raman spectroscopy can be used to ascertain the orientation of collagen fibres in the course of stretching, which information is essential for skin transplantation.