Wyniki wyszukiwania - Biblioteka Nauki

1

A microarray gene analysis of peripheral whole blood in normal adult male rats after long-term GH gene therapy

100%

Qin Y. , Tian Y.-P.

Cellular and Molecular Biology Letters

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2010

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tom 15

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nr 2

EN

The main aims of this study were to determine the effects of GH gene abuse/misuse in normal animals and to discover genes that could be used as candidate biomarkers for the detection of GH gene therapy abuse/misuse in humans. We determined the global gene expression profile of peripheral whole blood from normal adult male rats after long-term GH gene therapy using CapitalBio 27 K Rat Genome Oligo Arrays. Sixty one genes were found to be differentially expressed in GH gene-treated rats 24 weeks after receiving GH gene therapy, at a two-fold higher or lower level compared to the empty vector group (p < 0.05). These genes were mainly associated with angiogenesis, oncogenesis, apoptosis, immune networks, signaling pathways, general metabolism, type I diabetes mellitus, carbon fixation, cell adhesion molecules, and cytokine-cytokine receptor interaction. The results imply that exogenous GH gene expression in normal subjects is likely to induce cellular changes in the metabolism, signal pathways and immunity. A real-time qRT-PCR analysis of a selection of the genes confirmed the microarray data. Eight differently expressed genes were selected as candidate biomarkers from among these 61 genes. These 8 showed five-fold higher or lower expression levels after the GH gene transduction (p < 0.05). They were then validated in real-time PCR experiments using 15 single-treated blood samples and 10 control blood samples. In summary, we detected the gene expression profiles of rat peripheral whole blood after long-term GH gene therapy and screened eight genes as candidate biomarkers based on the microarray data. This will contribute to an increased mechanistic understanding of the effects of chronic GH gene therapy abuse/misuse in normal subjects.

2

Death effects assessment of PM2.5 pollution in China

80%

Xie Z. , Qin Y. , Zhang L. , Zhang R.

Polish Journal of Environmental Studies

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2018

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tom 27

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nr 4

EN

The provinces of China have suffered from severe PM2.5 pollution in recent years, presenting a significant threat to human health. Identifying associations between mortality rate and PM2.5 level is extremely useful for a range of purposes, such as the development of preventive measures, increasing health awareness, and establishing disaster warning systems. Based on remote sensing data, station monitoring data, and statistical data, this paper uses the exposure response function, regression analysis, and kriging to evaluate the number of deaths in China’s 31 provinces caused by PM2.5 pollution in 2015. Variations in the number of deaths and mortality rates in China under different PM2.5 concentration control standards have been simulated by a range of countries and organizations helping to develop optimal control standards for each province individually according to actual PM2.5 concentration. These results show that: 1) PM2.5 pollution has an important effect on the mortality rate in China. The rate caused by PM2.5 pollution in 2015 accounted for 1.75‰, or approximately 2.62 million people and 31.14% of all deaths in China. 2) Strict control standards for PM2.5 concentration can bring significant health benefits, with projections that if PM2.5 concentration in China’s provinces were controlled to the level set by China, the EU, Japan, USA, and Australia, the number of deaths caused by PM2.5 pollution would be reduced by approximately 0.95, 1.52, 2.02, 2.26, and 2.49 million people, respectively, or 36.24%, 58.08%, 79.91%, 86.47%, and 95.20% compared with baseline year data. 3) Choosing appropriate control targets for limiting PM2.5 concentrations in different provinces in China is an effective way to obtain optimal health benefits. Beijing, Tianjin, Hebei, Shandong, and Henan should adopt a 35 μg/m3 standard with a 25 μg/m3 standard appropriate for Shanxi, Liaoning, Jilin, Shanghai, Jiangsu, Zhejiang, Anhui, Hubei, Hunan, Chongqing, Shanxi, and Xinjiang; 13 provinces, including Inner Mongolia, Heilongjiang, Fujian, Jiangxi, Guangdong, Guangxi, Sichuan, Guizhou, Yunnan, Tibet, Gansu, Qinghai, and Ningxia, should adopt the 15 μg/m³ standard; and Hainan should consider choosing a 12 μg/m³ standard.

3

Effects of land use/cover change in the desert oasis system on topsoil carbon and nitrogen (middle of Heihe River basin, China)

80%

Niu R.-X. , Zhao X.-Y. , Liu J.-L. , Qin Y.

Polish Journal of Ecology

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2013

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tom Vol. 61, nr 1

45--54

EN

Land use/cover change (LUCC) is one of the main factors that influence the terrestrial carbon (C) and nitrogen (N) cycle. We examined the effects of land use/cover change on topsoil C, N, and microbial biomass C, N (MBC, MBN) and their relationship with other soil properties in the middle of Heihe river basin along a land use change gradient of 100-year farmland, 27-year farmland, 33-year pine forest, 28-year poplar forest, and 21-year shrubland, as well as native desert from which all the above cultivated systems are converted. Results revealed that land use conversion from native desert to the above cultivated ecosystems not only changed the basic eco-hydrological factors of the soil, such as improving the soil moisture and field capacity, decreasing the pH and salinity, but also altered the nutrient factors, such as improving the concentrations of soil organic C (SOC), total N (TN), MBC, MBN, NO3--N and NH4+-N,. With the increase of cultivated years, land use conversion had an increasing impact on the C and N sequestration and soil nutrients stabilization.

4

Optimal allocation of control targets for PM2.5 pollution in China’s Beijing-Tianjin-Hebei regions

80%

Xie Z. , Li Y. , Qin Y. , Zheng Z.

Polish Journal of Environmental Studies

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2019

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tom 28

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nr 5

EN

Based on the data of population size, industrial development, energy consumption and technological level from 2013 in the Beijing-Tianjin-Hebei region, the fairness of PM₂.₅ pollution emissions were analyzed using Gini coefficient and contribution coefficient. In addition, a reduction allocation plan of PM₂.₅ concentration by 2020 in 13 cities was determined according to a minimized model of Gini coefficient model. The results showed that: (1) Gini coefficients of industrial development and technological level were greater than 0.4, implying that the PM₂.₅ pollution emissions in the region were significantly unfair from the perspective of industry and technology, especially in the aspect of technological level. (2) The spatial distribution of industrial and technological contribution coefficients presented a downward trend from Beijing and Tianjin to the periphery, and cities in Hebei Province were central to the unfairness of PM₂.₅ pollution emissions across the whole region. (3) The reduction values of PM₂.₅ concentration were between 16.7 1μg/m³ and 57.49 μg/m³, and a reduction allocation plan of PM₂.₅ concentration could improve the overall fairness of PM₂.₅ pollution emissions in the Beijing-Tianjin-Hebei region, but the unfairness of PM₂.₅ pollution emissions would not change dramatically.

5

Supercooling points of Apis mellifera ligustica when performing different age-related tasks

80%

Li Y. , Wang S. , Qin Y.

Journal of Apicultural Science

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2012

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tom 56

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nr 1

6

Latitudinal diversity gradients in free-living microorganisms – Hoogenraadia a key genus in testate amoebae biogeography

80%

Bobrov A. , Qin Y. , Wilkinson D. M.

Acta Protozoologica

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2015

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tom 54

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nr 1

7

Preparation Process of Coating Interlayer and the Performance of EH40/2205-Clad Plate with Interlayer

80%

Feng K. K. , Yi Y. , Qin Y. , Jin H. R.

Archives of Metallurgy and Materials

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2023

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tom Vol. 68, iss. 2

591--598

EN

This study aimed to investigate the effect of different coating processes on interlayer coating using ProCAST software and identify the preferred coating process so as to prepare an EH40/2205 composite plate with a coating interlayer of Ni-5 Fe-15 Co (wt.%) displaying good performance. The preparation and characterization tests were conducted to analyze the interlayer coating, the diffusion of elements at the bonding interface and the mechanical properties of the hot-rolled composite plate. The results showed that the coating rate increased linearly with an increase in the initial coating temperature, pressure difference and the width ratio of the suction layer. The interlayer coating was complete under the guidance of optimized process parameters, and the test results and simulations confirmed each other. The coated interlayer successfully blocked the diffusion of elements between the bonding surfaces. The tensile strength of the rolled composite plate was 580 MPa, which met the needs of the project. The tensile shear fracture occurred at EH40, which proved that the plate was well bonded.

8

Effects of land use-cover change in the desert oasis system on topsoil carbon and nitrogen (middle of Heihe River basin, China)

80%

Niu R.-X. , Zhao X.-Y. , Liu J.-L. , Qin Y.

Polish Journal of Ecology

|

2013

|

tom 61

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nr 1

EN

Land use/cover change (LUCC) is one of the main factors that influence the terrestrial carbon (C) and nitrogen (N) cycle. We examined the effects of land use/cover change on topsoil C, N, and microbial biomass C, N (MBC, MBN) and their relationship with other soil properties in the middle of Heihe river basin along a land use change gradient of 100-year farmland, 27-year farmland, 33-year pine forest, 28-year poplar forest, and 21-year shrubland, as well as native desert from which all the above cultivated systems are converted. Results revealed that land use conversion from native desert to the above cultivated ecosystems not only changed the basic eco-hydrological factors of the soil, such as improving the soil moisture and field capacity, decreasing the pH and salinity, but also altered the nutrient factors, such as improving the concentrations of soil organic C (SOC), total N (TN), MBC, MBN, NO₃⁻ -N and NH₄⁺ -N,. With the increase of cultivated years, land use conversion had an increasing impact on the C and N sequestration and soil nutrients stabilization.

9

Pontigulasia pentangulostoma nov.spec., a new testate amoeba from the Da Jiuhu peatland of the Shennongjia Mountains, China

80%

Qin Y. , Xie S. , Gu Y. , Zhou X.

Acta Protozoologica

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2008

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tom 47

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nr 2

155-160

10

Temporal-spatial variation characteristics of soil erosion in the Pisha sandstone area, Loess Plateau, China

80%

Li Y. , Xie Z. , Qin Y. , Sun Y.

Polish Journal of Environmental Studies

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2019

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tom 28

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nr 4

EN

Soil erosion in the Pisha sandstone area of the Loess Plateau in China has become a severe environment issue that has raised concerns globally. The projects of ecological restoration in this area and their impact on soil erosion have been analyzed using the unmanned aerial vehicle remote sensing system (UAVRSS) and the revised universal soil loss equation (RUSLE) in the Two-Tiger Valley Basin in 2013 and 2015. Our findings show that: 1) The volume of soil erosion and average soil erosion modulus decreased from 126.24 t year-1 and 6465.295 t km-2 year−1 to 114.7 t year-1 and 6333.19 t km-2 year−1 between 2013 and 2015, respectively. 2) Spatial-temporal variations of soil erosion are extremely significant. All erosion grades recorded different degrees of decline across the study period, except for the level of severe erosion. 3) There is a significant positive correlation between slope degree and soil erosion. When the slope degree was <5°, the soil erosion modulus was 51.355 t km-2 year−1, accounting for only 0.87 % of total erosion in this area. When the slope degree was >35°, the soil erosion modulus attained 2574.413 t km-2 year−1, and the erosion amount accounted for 43.52% of total erosion. Although anti-erosion and the promotion of plant growth measures have achieved noticeable ecological benefits, the present situation of preventing and controlling soil and water loss is still severe.

11

Simple Three-level Neutral Point Voltage Balance Control Scheme Based on Carrier Overlapping SPWM

80%

Gong B. , Cheng S. , Qin Y.

Przegląd Elektrotechniczny

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2012

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tom R. 88, nr 12a

305-309

PL

W artykule omówiono możliwe przyczyny niezbalansowania napięcia punktu neutralnego w przekształtniku z diodami poziomującymi oraz wpływ na to napięcie nakładania się fal nośnych w modulacji. W przedstawionym schemacie modulacji nakładanie się fal jest wynikiem zwiększenia amplitudy jednej z tych fal. Przedstawiono dyskusję wpływu proponowanej techniki na zmiany napięcia punktu neutralnego oraz zależności między współczynnikiem modulacji, stopniem nakładania się fal i współczynnikiem mocy. Wyniki badań symulacyjnych potwierdzają skuteczność działania.

EN

To address the neutral point voltage balance problem of the diode clamped three-level inverter, this paper analyzes the causes of unbalanced neutral point voltage and studies the impact of the carriers overlap on the neutral point voltage. A simple neutral point voltage control scheme using carrier overlapping sinusoidal pulse width modulation (SPWM) is proposed. The proposed scheme does not change the modulation waves, the amplitude of one carrier is increased to overlap the other carrier, and the neutral point voltage can be maintained balance by increasing the carriers amplitudes. The influence of the vertical overlap of carriers on neutral point balance is investigated in depth. The relationship among the neutral point voltage variation, modulation index, overlap of the carriers, and power factor is discussed in this paper. Simulation results show the neutral point voltage balancing control strategy based on SPWM is effective.

12

The effect of hollow glass microspheres on the properties of high silica glass fiber fabric/liquid silicone rubber composite sheet

80%

Chen S. , Qin Y. , Song Y. , Wang B.

Polimery

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2018

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tom T. 63, nr 3

178--184

EN

In this study, high silica glass fiber fabric/liquid silicone rubber (HSGFF/LSR) composite sheet filled with hollow glass microspheres (HGM) was prepared. The effects of HGM content on the mechanical, thermal insulation and dynamic mechanical properties of the composite sheet were investigated. The results showed that the compatibility and interfacial properties between HGM and the matrix were improved after the HGM was treated with a silane coupling agent, KH550. Composite, in which the HGM content was 7 % by weight, shows the most advantageous mechanical, insulating and damping properties.

PL

Na bazie tkaniny z włókien kwarcowych (HSGFF) nasyconej ciekłym kauczukiem silikonowym (LSR) otrzymywano kompozyty napełniane mikrosferami szklanymi (HGM). Badano wpływ dodatku mikrosfer na właściwości mechaniczne, izolacyjność cieplną i właściwości dynamiczno-mechaniczne kompozytowych arkuszy. Stwierdzono, że modyfikacja mikrosfer szklanych za pomocą silanowego czynnika sprzęgającego KH550 poprawiła kompatybilność i oddziaływania międzyfazowe cząsteczek HGM i nasyconej ciekłym kauczukiem tkaniny z włókien szklanych. Najkorzystniejsze właściwości mechaniczne, izolacyjne i tłumiące wykazywał kompozyt, w którym zawartość HGM wynosiła 7 % mas.

13

Ecological service evaluation: an empirical study on the Central Loess Plateau, China

80%

Li Y. , Zhang P. , Qin Y.

Polish Journal of Environmental Studies

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2020

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tom 29

|

nr 2

14

Geoarchaeological and environmental work at the sacred animal necropolis, north Saqqara, Egypt

71%

Nicholson P. T. , Harrison J. , Ikram S. , Early E. , Qin Y.

Studia Quaternaria

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2013

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tom Vol. 30, Nr 2

83--89

EN

This paper summarises work undertaken during the Catacombs of Anubis project which has examined the Dog Catacomb at North Saqqara. It examines the condition and natural decay of the monument as well as looking at the environs of the Lake of Abusir at the northern end of the site.

15

Morphological redescription and morphogenesis of Urosoma macrostyla (Wrześniowski, 1866) Berger, 1999 (Ciliophora, Hypotrichida)

71%

Qin Y. , Qiu Z. , Shao C. , Warren A. , Shen Z.

Acta Protozoologica

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2011

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tom 50

|

nr 3

16

Effects of livestock exclusion on soil physical and biochemical properties of a desert rangeland

71%

Qin Y. , Niu D. , Kang J. , Zhou Y. , Li X.

Polish Journal of Environmental Studies

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2015

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tom 24

|

nr 6

17

Fully-phase optical image encryption in diffractive-imaging scheme with QR-code-based random illumination

71%

Wang Z. , Zhang Y. , Gong Q. , Li S. , Qin Y.

Optica Applicata

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2017

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tom Vol. 47, nr 2

233--243

EN

Based on a fully phase encoding and phase retrieval algorithm, a diffractive-imaging-based optical encryption scheme with random illumination is proposed. In the encryption process, a QR code image is placed in the optic path to modulate the incident light and thus generate a random illumination, which has been demonstrated to enable the proposed scheme to resist the multi-slice ptychographic phase retrieval algorithm attack. The plaintext is phase-encoded, and then encrypted by two random phase masks. The diffraction pattern in the output plane is recorded as ciphertext by a CCD camera. For decryption, an iterative phase retrieval algorithm with median filtering operation is implemented. Simulation results demonstrate the effectiveness, security, and robustness of the proposal.

18

Effects of gibberellins A4 on budbreak, antioxidant enzymes’ activity and proline content of flower buds in sweet cherry (Prunus avium)

61%

Cai B. , Wang H. , Liu T. , Zhuang W. , Wang Z. , Qu S. , Qin Y.

Acta Physiologiae Plantarum

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2019

|

tom 41

|

nr 06

EN

Chilling accumulation is required for deciduous trees to maintain its normal growth and development. However, warm winters appeared more and more frequently, which hindered severely the normal growth and yield of fruit trees. To avoid these problems, artificial dormancy breaking agents are widely used. In our study, the effect of mineral oil, hydrogen cyanamide and gibberellins A₄ (GA₄) on budbreak were evaluated in sweet cherry (Prunus avium), which indicated that GA₄ treatment hastened the date of flower budbreak and increased the percentage of budbreak compared with the other treatments. To better understand the mechanism of GA₄-induced budbreak, the contents of antioxidant enzymes’ activity and proline in sweet cherry flower buds treated with GA₄ and water were evaluated. There was a sharp decrease of catalase (CAT) activity after 5 days of GA₄ treatment and then an increase of CAT activity after 10 days of GA₄ treatment. However, there was a sharp increase of superoxide dismutase (SOD), peroxidase (POD) and ascorbate peroxidase (APX) after 5 days of GA₄ treatment and then a decrease of these enzyme activities after 10 days of GA₄ treatment. There was a transient increase in hydrogen peroxide (H₂O₂) content and proline content after 5 days of GA₄ treatment and a decrease after 10 days of GA₄ treatment. However, there were only small fluctuations after water treatment, which indicated that temporary oxidative stress may contribute to the dormancy release of flower buds in the sweet cherry treated with GA₄ through the regulation of H₂O₂ content coincided with the changes of antioxidant defense system.

19

How Chlorella sorokiniana and its high tolerance to Pb might be a potential Pb biosorbent

61%

Liang S. , Kang Y. , Zeng L. , Qin Y. , Wang L. , Zhang Q. , Luo J.

Polish Journal of Environmental Studies

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2017

|

tom 26

|

nr 3

EN

The link between the acute toxicity of heavy metals on algae and the bioadsorption capacity of heavy metals by algae has seldom been reported. In the present study, an acute toxicity experiment was carried out to assess the toxic effects of Pb, Cu, and Cd for Chlorella sorokiniana, and the 96 h IC₅₀ values were 0.249 mg/L, 0.485 mg/L, 46.108 mg/L, and 21.00 mg/L for Cu, Cd, Pb (total), and Pb (free ion), respectively, which implied that Chlorella sorokiniana showed high tolerance to Pb compared to Cu and Cd. Pb distribution analysis indicated that 73.40% to 98.15% of free Pb ions were accumulated on the algae cell wall to avoid further intracellular accumulation, resulting in irreversible metabolic disorders. Then the adsorption capacity of Chlorella was explored. It could be found that the Langmuir model (the R² were 0.988 and 0.962 for living and lifelss cells, respectively) was fit to explain the adsorption equilibrium data and the qₑ calculated by this model were 1.54 and 2.97 mg /10¹⁰ cells for living and lifeless cells, respectively, which was consistent with the experimental result. In the competitive adsorption, Chlorella exhibited a greater affinity for Pb with the higher removal rate compared to Cu and Ni. Therefore, the renewable Chlorella sorokiniana and its dramatic resistance to Pb may serve as a potential biosorbent for Pb in the future.

20

Temperature field analysis of optical coatings induced by millisecond and nanosecond lasers

61%

Wang B. , Qin Y. , Ni X. , Shen Z. , Lu J. , Wang X.

Optica Applicata

|

2012

|

tom Vol. 42, nr 4

783--793

EN

To study the differences between long-pulse and short-pulse laser-induced damage in optical dielectric thin films, temperature distributions in single-layer HfO2 films, multi-layer HfO2/SiO2 films, and HfO2 films with high-absorptive inclusions induced by 1 ms and 10 ns lasers are analyzed based on the temperature field theory. Through our calculations, the damage property differences between millisecond and nanosecond lasers are summarized. The results for single-layer films show that 1 ms laser is easier to damage the substrate than 10 ns laser. For multi-layer films, the laser field effect is weaker when irradiating by 1 ms laser. Furthermore, when inclusions are introduced, the film is easier to be damaged by 10 ns laser, which means that 10 ns laser is more sensitive to the inclusions.