The role and importance of a multimodal transport network for the territory of the Republic of Sakha (Yakutia) – a region with harsh climatic conditions are defined. The experience of European and, in particular, Scandinavian countries is analyzed with the integration of multimodal technologies into a real operating transport and logistics network. The transport and logistics potential of Yakutia is analyzed. The importance of settlements as potential multimodal centers of transport and logistics network based on combinatorial optimization methods is determined.