The effect of dietary inclusion of amaranth meal on hematology and blood biochemistry, of rainbow trout Oncorhynchus mykiss was examined. The fish (mean length 35.2 ± 0.6 cm; mean weight 524.8 ± 28.5 g) were divided into three groups: a reference group (RF) fed commercial trout pellet and two experimental groups (EF5 and EF10) fed feeds containing 5.0% and 10.0% of amaranth meal respectively. Determined indices covered: packed cell volume, red blood cell count, hemoglobin concentration, mean cell volume, mean cell hemoglobin concentration, mean hemoglobin content, inorganic phosphates, total proteins, albumins, globulins, ammonia, triacylglycerols, glucose, and the activity of creatine kinase, alkaline phosphatase and aspartate aminotransferase. Supplementation of feed with amaranth meal significantly raised levels of blood glucose, cholesterol, total protein, ammonia, creatinine and aspartate aminotransferase activity in trout blood. These results indicate that inclusion of amaranth meal in extruded diets for rainbow trout can get negative effect on liver and blood biochemistry profile
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