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PL
Scharakteryzowano 68 szczepów pałeczek Salmonella opornych na antybiotyki oksy-imino-betalaktamowe należących do 6 typów serologicznych, wybranych spośród 239 opornych na ampicylinę szczepów pałeczek Salmonella izolowanych w Polsce w latach 1999-2004 z próbek materialu klinicznego. Stwierdzono, że większość badanych szczepów wytwarzała p-Iaktamazę TEM-1 o pl=5,4 oraz p-laktamazę o rozszerzonym spektrum substratowym CTX-M-3 o pl=8,4. Wszystkie badane szczepy S. Thompson i jeden ze szczepów S. Typhimurium wytwarzał enzym SHV-5 o pl=8,2. Jest to pierwsze doniesienie o produkcji SHV-5 przez pałeczki Salmonella w Polsce.
EN
Extended - spectrum ß-lactamases (ESBLs) are enzymes manifesting considerable hydrolyzing activity on a wide variety of ß-lactam antibiotics including oxyiminocephalosporins and aztreonam. In the study reported here we investigated the types of ESBL produced by Salmonella enterica subsp. enterica strains isolated from clinical samples in the microbiological laboratories of sanitary-epidemiological units in Poland from 1999 to 2004. Among 239 ampicilline-resistant Salmonella enterica subsp. enterica strains isolated from clinical samples in the microbiological laboratories of sanitary-epidemiological units in Poland, 68 isolates of oximino-beta-lactams resistant of 6 serovars were found. There were 16 epidemiological unrelated strains (6 isolates of S.Enteritids, S isolates of S.Thompson, 3 isolates of S.Typhimurium, onefold isolate of S.Muenster and S. enterica 1,9,12:-:-) coming from different areas of country and 52 epidemiologically related isolates of S. Oranienburg, coming from a prolonged outbreak in an orphanage in Łódź. All the strains were identified as the ESBLs producers . The molecular analysis relevead that most of them expressed CTX-M-3 ESBL which is widely observed in Poland and additional enzyme TEM-1. All tested isolates of S.Thompson and one of three S. Typhimurium isolates were found to produce SHV-5 ESBL. This is the first report regarding the presence of SHV-5 in the genus Salmonella in Poland.
EN
Background: Epilepsy is one of the most common neurological disorders, with more than 400,000 individuals in Poland (about 1% of the population) affected. Epilepsy complicates approximately 0.5% of pregnancies. Aim of the study: To determine the level of knowledge that neurologists and gynaecologists have about reproductive and maternity issues for women with epilepsy. Material and methods: This study included 141 neurologists and physicians undergoing specialist training in neurology as well as 72 gynaecologists and physicians undergoing specialist training in gynaecology. A validated questionnaire was used to survey these neurologists and gynaecologists, who worked in Silesia Province. Results: In the group of physicians advising on contraception, significantly (p = 0.003) more gynaecologists than neurologists recommended hormonal birth control. Significantly more (p = 0.031) neurologists than gynaecologists believed that monotherapy with antiepileptic medications should be aimed for before a planned pregnancy in women with epilepsy. More than a half of the surveyed physicians (56.8%) believed that pregnant women with epilepsy can have a natural delivery. Conclusions: On the basis of these results, we have concluded that gynaecologists and, to a lesser extent, neurologists should have more extensive knowledge regarding reproductive and maternity issues for women with epilepsy. We further propose that close collaboration between neurologists and gynaecologists in the care of epileptic women is necessary.
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