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1 Acta Parasitologica

1 1997

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Immunopathology of alveolar echinococcosis

100%

Dar F. K. , Alkarmi T.

tom 42

nr 1

The pathogenesis of alveolar echonococcosis caused by the metacestode of Echinococcus multilocularis is a process involving the host-parasite interface with both local and distant systemic effects. The survival strategy of the parasite is to continuously subvert the host defenses just as the host responds to contain the infection. There is a complex of signal molecules mediating between parasite-elaborated factors and specific and non specific cellular immune responses behind the gross pathological picture of a space-occupying lesion. This paper attempts to summarize the relationship of experimental findings with the clinicopathological picture by outlining pathways that may be involved in the process of pathogenesis.