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EN
Sieklucka-Dziuba, M., Wamil, A., Kleinrok, Z.: The effect of frontal cortex lesion on the activity of the dopaminergic system in rat. striatum. Acta physiol, pol., 1988, 39 (4): 254-260. The experiment was carried out on male Wistar rats weighing 180-220 g with lesion in the cortex of the frontal lobe. The activity of the dopaminergic system was studied by means of behavioural tests such as determination of spontaneous motor activity, apomorphine-induced stereotypy,haloperidol-induced catalepsy. Increased intensity of stereotypy was observed reaching a maximum 14 days after frontal lobe damage. Moreover, a slight tendency was observed lor inhibition of haloperidol-induced catalepsy without changes in the spontaneous motor activity of the animals. Biochemical investigations demonstrated reduced dopamine content in the striatum on the side of the lesion.
EN
This study was carried out in a car factory at workplaces in various states of activity. The measurements of substances enlisted as carcinogenic found at workplaces in some departments in 1995-1997 was carried out as well as the evaluation of microclimatic conditions and the evaluation of sick absenteism in the whole factory. Analysis of results revealed that microclimates in the rooms in the studied departments did not exceed permissible hygienic standards, except for some workplaces in the suspension springs department and the tool room. The analysis of exposure to particular/specific factors in 1995-1997 enlisted among carcinogenic substances did not reveal any toxicological health hazard. Sick absenteism in the whole factory and studied departments in the analyzed period varied. The prevailing group of diseases were diseases of the respiratory system. Morbidity from cancer was low.
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