Wyniki wyszukiwania - Biblioteka Nauki

1

The vocal competence of children and youth - diagnostic research

100%

Kamińska B.

Interdisciplinary Studies in Musicology

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2011

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nr 10

87-96

PL

There is a prevailing conviction that Poles cannot sing. The custom of singing has died out in families, and it is even waning in music lessons in school. There is a general perception that singing skills are conditioned by the possession of special musical abilities and that not everyone can master them. This article presents the results of my diagnostic research carried out at the end of the 1980s and reprised by other scholars in recent years. Because the same research method and procedures were used in all this research, it is possible to compare the results and observe any changes in the level of singing skills over the space of around twenty years. The research signals an alarming situation in respect to such an important musical competence as singing. After the twenty years that have passed since the first research, we observe a decline in the ability to sing among children and youngsters.

2

Kaizen as a Method of Management Improvement in Small Production Companies

100%

Kamińska B.

Przedsiębiorczość i Zarządzanie

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2015

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tom 16

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nr 2

157-170

EN

„Quality is not everything but everything is nothing without quality”. The famous quotation from K. Ishikawa brings to our attention the fact that nowadays quality is one of strategic concepts from the point of view of functioning of companies, especially production-oriented ones. The lack of quality often eliminates a product from the basket of potential further choices. That means that quality is a prerequisite in the contemporary, highly competitive and saturated market. In order to ensure quality, enterprises introduce various concepts and methods to support quality management. They include, among others, the kaizen philosophy, which allows to minimize unnecessary actions (losses). It is especially recommended to small firms as an inexpensive method assuring high quality of products because they are constantly improved, which, in turn, guarantees maintaining a high position among competitors. This article aims to introduce the concept of kaizen by describing how it works and considering whether it can be successful in Polish companies.

3

Zmiany w układzie stomatognatycznym u osób starszych w aspekcie gerontologopedii

100%

Kamińska B.

Conversatoria Linguistica

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2017

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nr 11

83-91

EN

This article lists and briefly describe sage related changes in the stomatognathicsystem. And that established understanding, may become a serious support to the work of elderlypeople’s therapists. The changed to the stomatognathic system affect both general healthcondition, chewing, swallowing, speaking abilities, as well as wellbeing and self esteem of seniors.Moreover, at present, the knowledge on stomatognathic in elderly is fairly underestimatedby doctors and other experts. The significant lack of developed logopaedic thesis on this aspectalso brings in more unawareness.

4

Options in Corporate Finance Management

100%

Kamińska B.

Przedsiębiorczość i Zarządzanie

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2014

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tom 15

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nr 1

69-81

EN

Although there are many opinions critical of options, especially after the 2008 scandal, they are becoming increasingly popular in Poland again. Therefore, issues connected with options are not only the subject of interest in academic circles again but also arouse interest of economic entities, allowing enterprises to assess a variety of action strategies. Those instruments enable planning safeguards to protect against various negative future scenarios. Hence, it comes as no surprise that there has been an increase in the number and variety of enterprises that have accepted options as a way to plan for their future. The article provides a brief presentation of options. It also describes one of their pricing methods. Light of the foregoing has been hypothesized that 'valuation of options using mathematical calculators using the binomial model is an effective tool for supporting management positions in futures instruments’.

5

Przyczyny i konsekwencje zmian w narządzie żucia u osób starszych

63%

Kamińska B. , Kaczorowska-Bray K.

Logopedia Silesiana

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2017

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nr 6

46-56

PL

Causes and Consequences of Changes in Chewing Organ of the ElderlyThe article discusses the phenomena connected with physiological changes occurring in the stomatognathic system of the elderly. It points to their relation with the activities of chewing and swallowing as well as the general state of health and social functioning of older people. The issues addressed in the text are of vital importance not only for dentists and geriatrists, but also for speech therapists and other specialists working with seniors.Key words: gerontologopaedics, stomatognathic system, chewing organ

6

Professional Evaluation. Application of the PageRank Algorithm in Employee Rating

63%

Kamińska B. , Szymańczyk K.

Przedsiębiorczość i Zarządzanie

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2014

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tom 15

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nr 2

37-50

EN

Appraisal is a tool used by both management and employees to attain their goals. Properly carried out employee performance appraisal allows to monitor the employee's actions and provides information on the level of his or her performance. Feedback in the form of appraisal motivates the employee to work more effectively and productively. Appraisal also enables to shape the personnel policy – it allows to chart employee career paths and determine training needs of an organization. For appraisal, however, to fulfil the attributed role, it needs to be carried out in a professional manner. The aim of the article is to draw attention to the importance of employee performance appraisal in the personnel management process and to provide information on the core principles of appraisal. It describes, among others, determinants, criteria as well as selected methods and techniques of appraisal. An interesting point can be the use of the PageRank algorithm which can be a good solution for rating employees.

7

Coexistence of type 1 diabetes mellitus and spinal muscular atrophy in an 8-year-old girl: a case report

38%

Borkowska A. , Jankowska A. , Szlagatys-Sidorkiewicz A. , Sztangierska B. , Liberek A. , Plata-Nazar K. , Kamińska B.

Acta Biochimica Polonica

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2015

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tom 62

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nr 1

167-168

EN

The spinal muscular atrophy is a rare autosomal recessive genetic disease characterized by the progressive loss of muscular strength. In its natural course the disease leads to death. Diabetes mellitus type 1 is an autoimmune metabolic disorder characterized by the disturbed insulin synthesis. This is a case report of an 8-year-old girl suffering from Werdnig Hoffman disease in whom DM1 was diagnosed. The unspecific clinical manifestation and diagnostic difficulties are presented in this paper. To the authors' knowledge, this is the first publication concerning the co-existence of these two medical conditions.

8

Fecal lactoferrin, a marker of intestinal inflammation in children with inflammatory bowel disease

38%

Borkowska A. , Liberek A. , Łuczak G. , Jankowska A. , Plata-Nazar K. , Korzon M. , Kamińska B.

Acta Biochimica Polonica

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2015

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tom 62

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nr 3

541-545

EN

The aim of this study was to analyze the usefulness of fecal lactoferrin in the diagnosis and monitoring of inflammatory bowel disease (IBD) in children. The study included 52 children with IBD (24 with Crohn's disease and 28 with ulcerative colitis) aged between 0.92 and 18 years, and 41 IBD-free controls of similar age. Fecal concentration of lactoferrin was determined with a quantitative immunoenzymatic test. Fecal concentration of lactoferrin in children with IBD was significantly higher than in the controls. The cut-off value of fecal lactoferrin concentration optimally distinguishing between the children with IBD and the controls was identified as 13 μg/g. The sensitivity and specificity of this cut-off value equaled 80.7% and 92.7%, respectively, and its positive and negative prognostic values were 96.8% and 63.3%, respectively. Patients diagnosed with moderate Crohn's disease had significantly higher fecal concentrations of lactoferrin than children with the mild or inactive disease. Similarly, children with moderate ulcerative colitis showed significantly higher fecal concentrations of lactoferrin than individuals with the mild condition. No significant relationship was found between the fecal concentration of lactoferrin and the severity of endoscopic lesions. Patients with IBD and a positive result of fecal occult blood test were characterized by significantly higher concentrations of lactoferrin than the individuals with IBD and a negative result of this test. In conclusion, fecal concentration of lactoferrin seems to be a useful parameter for diagnosis and monitoring of IBD in children.

9

Graves' disease, celiac disease and liver function abnormalities in a patient - clinical manifestation and diagnostic difficulties

32%

Góra-Gębka M. , Woźniak M. , Cielecka-Kuszyk J. , Korpal-Szczyrska M. , Sznurkowska K. , Zagierski M. , Jankowska I. , Plata-Nazar K. , Kamińska B. , Liberek A.

Acta Biochimica Polonica

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2014

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tom 61

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nr 2

281-284

EN

Autoimmune diseases due to probable common pathogenesis tend to coexist in some patients. Complex clinical presentation with diverse timing of particular symptoms and sophisticated treatment with numerous side effects, may cause diagnostic difficulties, especially in children. The paper presents diagnostic difficulties and pitfalls in a child with Graves' disease, celiac disease and liver function abnormalities.

10

Helicobacter pylori increases expression of proapoptotic markers Fas and FasL on CD4 lymphocytes in children

32%

Kotłowska-Kmieć A. , Bąkowska A. , Szarszewski A. , Kamińska B. , Łuczak G. , Radys W. , Landowski P. , Brodzicki J. , Korzon M. , Liberek A.

Acta Biochimica Polonica

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2009

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tom 56

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nr 3

433-438

EN

The pathomechanism of Helicobacter pylori action upon gastric mucosa and its role in the pathogenesis of gastritis have not been fully elucidated. The aim of this study was to evaluate the most prevalent lymphocyte subpopulations of the gastric mucosa in gastritis in children, as well as to evaluate the expression of Fas and Fas ligand receptors (FasL), periapoptotic markers of gastric mucosa lymphocytes before and after H. pylori eradication. Forty nine patients aged 6 to 17 years, investigated due to chronic abdominal pain, were studied. The obtained tissue samples were analysed by immunohistochemistry. Different lymphocyte subsets were quantified on the basis of surface antigen expression (CD3, CD4, CD8, CD20), secreted cytokines (IL-4, IL-6, IFNγ) and Fas and FasL proteins in the gastric mucosa. B and T helper lymphocytes were found to play a major role in the inflammatory infiltration in the gastric mucosa in children during H. pylori infection. Their expression was found to decrease after eradication. The enhanced expression of Fas receptor on lymphocytes before treatment and a decrease of this expression after eradication of H. pylori were shown. It was demonstrated that there is a correlation between CD4 and Fas receptor expression that may induce apoptosis of the helper lymphocytes in infected children.

11

TGF-β1, IL-10 and IL-4 in colostrum of allergic and nonallergic mothers

32%

Marek A. , Zagierski M. , Liberek A. , Aleksandrowicz E. , Korzon M. , Krzykowski G. , Kamińska B. , Szlagatys-Sidorkiewicz A.

Acta Biochimica Polonica

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2009

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tom 56

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nr 3

411-414

EN

Objective: To determine transforming growth factor (TGF) β1, interleukin (IL) 4, and IL-10 concentrations in human milk and to assess the relationship between allergic disorders in mothers and the content of the interleukins in their milk. Material and methods: Thirty allergic and 46 healthy mothers were included in the study. Colostrum was collected 2-3 days after delivery. Cytokine concentrations were determined with commercial enzyme-linked immunosorbent systems. Results: TGF-β1was found in milk from 23 women in the control group (53.49%) and 11 in the allergy group (37.93%). When TGF-β1 was present, the median concentration was higher in the allergy group than in the control (61.5 and 30.4 pg/mL, respectively; P < 0.004). IL-10 was present in the colostrum of all the women and the median IL-10 concentration did not differ between the allergy (50.5 pg/mL) and control (51.5 pg/mL) groups. The probability of occurrence of a positive IL-4 value in the allergy group was greater than in the control group (chi-squared [df=1] = 2.60, P < 0.053). Median IL-4 level did not differ significantly between the two groups (0.5 and 0.5 pg/mL respectively). Conclusions: TGF-β1 was detected less often in the colostrum of allergic mothers than in that of mothers without allergy (but the difference was not statistically significant). IL-4 was found more often in the colostrum of allergic mothers than nonallergic ones. The allergy status did not correlate with IL-10 concentration.

12

Peripheral regulatory T cells and anti-inflammatory cytokines in children with juvenile idiopathic arthritis

32%

Sznurkowska K. , Boćkowska M. , Zieliński M. , Plata-Nazar K. , Trzonkowski P. , Liberek A. , Kamińska B. , Szlagatys-Sidorkiewicz A.

Acta Biochimica Polonica

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2018

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tom 65

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nr 1

119-123

EN

Background: Juvenile idiopathic arthritis (JIA) is a chronic, heterogenous inflammatory disease of unclear pathogenesis. JIA is hypothesized to be linked to a defective immune regulation. Anti-inflammatory cytokines belong to the best known regulatory factors. T-regulatory cells are a crucial cellular component of immune tolerance. One of their functions is synthesis of interleukin 10 (IL-10) and transforming growth factor beta1 (TGF-β1). The aim of this study was to determine the proportion of T-regulatory cells (CD4+CD25highFOXP3+) in peripheral blood, and serum levels of TGF-β1 and IL-10 in patients with JIA. Methods: The study included 25 patients with newly diagnosed JIA: oligoarthritis (n=17) and polyarthritis (n=8). The control group was comprised of 17 healthy children. CD4+CD25highFOXP3+ T cells in peripheral blood were quantified by means of three-color flow cytometry. Serum concentrations of TGF-β1 and IL-10 were estimated with ELISA. Results: The proportion of peripheral CD4+CD25highFOXP3+ cells in patients with JIA was significantly higher than in the controls (p=0.04). The two groups did not differ significantly in terms of their TGF-β1 and IL-10 concentrations. Conclusions: At the time of diagnosis, children with JIA presented with an elevated proportion of T-regulatory cells (CD4+CD25highFOXP3+) in peripheral blood. Anti-inflammatory cytokines, IL-10 and TGF-β1, are not upregulated in the serum of patients with JIA, and therefore should not be considered as biomarkers of this condition.

13

Clinical parameters of inflammatory bowel disease in children do not correlate with four common polymorphisms of the transforming growth factor β1 gene

26%

Liberek A. , Jakóbkiewicz-Banecka J. , Kloska A. , Świderska J. , Kmieć Z. , Łuczak G. , Wierzbicki P. , Liberek T. , Marek K. , Plata-Nazar K. , Sikorska-Wiśniewska G. , Kamińska B. , Węgrzyn G.

Acta Biochimica Polonica

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2011

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tom 58

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nr 4

641-644

EN

Transforming growth factor β1 (TGF-β1) is a cytokine affecting cell proliferation and development, which also has an immunomodulatory activity. Correlations between polymorphisms of the TGF-β1 gene and clinical parameters of inflammatory bowel disease (IBD) were reported previously in adults. Here, we tested whether such correlations occur in pediatric patients suffering from IBD. One hundred and four pediatric IBD patients were involved in this study. Among them, 36 were diagnosed with Crohn's Disease (CD) and 68 were diagnosed with ulcerative colitis (UC). The control group consisted of 103 children, in which IBD was excluded. TGF-β1 levels were determined in plasma and intestinal mucosa samples. The presence of the TGF β1 protein and the amount of TGF β1 mRNA were estimated in intestinal mucosa by immunohistochemistry and reverse transcription Real-Time PCR, respectively. Four common polymorphisms of the TGF-β1 gene were investigated: -800G/A, -509C/T, 869T/C and 915G/C. No significant correlation between TGF-β1 genotypes and (i) TGF-β1 levels in plasma and tissue samples, (ii) TGF-β1 gene expression efficiency in intestinal mucosa, (iii) IBD clinical parameters and (iv) inflammatory activity could be detected in children suffering from IBD. We conclude that, contrary to previous suggestions, the four common polymorphisms of the TGF-β1 gene do not influence the susceptibility to or clinical parameters of IBD in the tested population of children.