Wyniki wyszukiwania - Biblioteka Nauki

1

Shape stability of laminated timber

100%

Gaborik J. , Kulik J.

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2011

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tom 74

2

Światowe trendy robotyki a wyzwania technologiczne polskich MŚP

100%

Kulik J. , Wojtczak Ł.

Pomiary Automatyka Robotyka

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2015

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tom R. 19, nr 4

79--86

PL

Przedmiotem artykułu jest przedstawienie specyfiki robotyzacji małych i średnich przedsiębiorstw (MŚP) produkcyjnych w Polsce. Omówione zostały wyzwania robotyki przemysłowej na rynku krajowym. Analizę przeprowadzono z punktu widzenia rzeczywistych wdrożeń i przeglądu polskiego rynku na tle światowych trendów rozwojowych i aktualnych kierunków rozwoju robotyki przemysłowej na świecie. Jednocześnie w artykule przedstawiona jest polemika dwóch opinii. Pierwsza z nich przedstawia polski rynek robotyki jako bliźniaczy do wzorców światowych, ale nieco zapóźniony oraz prezentuje ten temat pod innym kątem, z pominięciem pewnego etapu w rozwoju systemów produkcji. Druga opinia jest wynikiem obserwowanych praktycznych różnic już na etapie samej integracji systemów zrobotyzowanych, o czym również jest mowa w artykule.

EN

This article presents a specific way of robotization of manufacturing SME’s in Poland. There are introduced challenges for industrial robotics in Polish market. The analysis was conducted from the perspective of real implementation and review of the Polish market on the background of global development trends and current directions of development of industrial robots worldwide. We also show a discussion between two opinions; the first one tells that in Poland robotics market is similar to the best worldwide patterns, and the second one which shows that robotization in Poland had lost some steps – they are missed. The second attitude results in practical differences already in robotic systems integration itself, which is also mentioned in the article.

3

Robotyzacja, możliwości rosną - nie tylko spajanie

100%

Wojtczak Ł. , Kulik J.

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tom Nr 3 (21)

14

PL

Robotyzacja w chwili obecnej kojarzy się szczególnie mocno z przemysłem samochodowym. Prace wykonywane tam przez manipulatory są powtarzalne i w pełni nadają się do automatyzacji. Obecnie również, coraz szerzej, inne sektory produkcji sięgają po stanowiska z robotami. Dostrzegając coraz więcej ich zalet, w tym szczególnie ważną dla użytkownika, rosnącą samodzielność manipulatorów.

4

Properties of densified laminated aspen wood at bend loading

80%

Gaborik J. , Dudas J. , Kulik J. , Raucina M.

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2011

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tom 74

5

Detection of t(14;18)-bearing cells by real-time PCR for qantification of residual disease in follicular non-Hodgkin’s lymphomas

80%

Purzycka J. , Kulik J. , Paszkiewicz-Kozik E. , Fabisiewicz A.

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nr Supplement 1

6

Aspekty ekonomiczne biotechnologii w Europie

80%

Kulik J.

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1989

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nr 3-4

7

Detection of CA IX-expressing tumour cells in the lymph nodes by reverse transcriptase- polymerase chain reaction (RT-PCR) in vulvar carcinoma

71%

Kowalewska M. , Kulik J. , Radziszewski J. , Nasierowska-Guttmajer A. , Siedlecki J.

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nr Supplement 1

8

Real-time quantitative PCR in monitoring minimal residual disease in follicular lymphoma patients

61%

Tysarowski A. , Kulik J. , Paszkiewicz-Kozik E. , Fabisiewicz A. , Walewski J. , Siedlecki J. A.

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tom 53

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nr Supplement 1

9

Usefulness od real-time PCR in long-term follow-up of follicular lymphoma patients

61%

Tysarowski A. , Fabisiewicz A. , Paszkiewicz-Kozik E. , Kulik J. , Walewski J. , Siedlecki J. A.

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tom 54

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nr 1

EN

The aim of this study was to evaluate the usefulness of quantitative real-time PCR (RQ-PCR) for the monitoring of molecular remission in follicular lymphoma (FL) patients during long-term follow-up. RQ-PCR by the use of TaqMan® detection system is a sensitive tool to monitor minimal residual disease (MRD) in FL through amplification of the t(14;18) fusion gene during and post-therapy. In most cases the breakpoint region occurs within the major breakpoint region (MBR). Among 75 patients diagnosed with FL, cells harboring the fusion gene BCL2/JH were found in peripheral blood of 31 patients (41%). We further monitored 30 of these patients in a period varying from 6 months to 5 years by RQ-PCR. In our study the level indicating the possibility of the presence of MRD was established at more than five t(14;18)-positive cells in the background of 83000 normal cells. The results of this work also confirmed that the presence of MRD detected by RQ-PCR is an indication for careful observation of patients because of a higher risk of disease recurrence.

10

Detection of circulating breast cancer cells in peripheral blood by a two-marker reverse transcriptase-polymerase chain reaction assay

61%

Fabisiewicz A. , Kulik J. , Kober P. , Brewczynska E. , Pienkowski T. , Siedlecki J. A.

Acta Biochimica Polonica

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2004

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tom 51

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nr 3

EN

The aim of this study was to use a two-marker assay for the detection of breast cancer cells circulating in patients' blood. We have applied a PCR-based methodology to follow up the possibility of the development of metastatic disease in stage I and II patients who had undergone curative surgery. Since the number of circulating cancer cells in peripheral blood is very low, the technique for their detection needs to be not only highly sensitive, but also very specific. The reverse transcriptase-polymerase chain reaction (RT-PCR) technique may improve the sensitivity of breast cancer cell detection up to only a few cells per one million. The principle of the RT-PCR assay is to amplify a messenger RNA characteristic for breast epithelial cells in a blood sample. Since we do not expect such cells to be circulating in peripheral blood of healthy subjects, detection of the characteristic mRNA should indicate the presence of circulating breast cancer cells. We analyzed the usefulness of three mRNA markers: cytokeratin 19 (CK19), mammaglobin (hMAM) and S subunit of human chorionic gonadotropin (S-hCG) for this test. Blood samples (112) were obtained from 55 patients, in stages I and II, with or without metastasis to regional lymph nodes (N0 or N1). We found that a two-marker assay increases the sensitivity of detection of breast cancer cells in comparison with a single-marker one. Combination of two tumor-specific mRNA markers, hMAM/CK19 or S-hCG/CK19, allowed the detection of circulating breast cancer cells in 65% of N1 patients and 38% of N0 patients. By comparison, the combination hMAM/-hCG allowed the detection of circulating breast cancer cells in the blood of 68% of N1 patients and 46% of N0 patients. Addition of the third marker did not significantly increase the detection sensitivity.