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EN
The study was carried out on 24 animals chosen from a herd with many cases of diseases in the first period of lactation after parturition. The period from the 7th month of pregnancy to the 5th month of lactation was analysed taking into account the kind of nourishment, housing, productivity and also physical examinations every month, as well as the basic blood indexes. It was found that the health disturbances of the primiparous cows after parturition were caused by lack of movement, low-protein nourishment during pregnancy, stress due to change of cowsheds and rapid administration of dry foodstuffs whose quantity was related entirely with milk production. The above mentioned errors brought about marked changes in the metabolic indexes of blood indicated by high lipolysis and liver disturbances; all these factors facilitated the development of various diseases. Special attention was paid to hypoproteinaemia and hypocholesteraemia before parturition and high indexes of bilirubin and AspAT in the first half of lactation.
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nr 10
506-511
EN
The distribution of Mg and Ca contents in sera was assessed after the administration of magnesium and magnesium-calcium preparations in 28 normal cows. The experiment was carried out on four groups of animals. The following were evaluated: 25 per cent magnesium sulfu- ricum, 25 per cent magnesium sulfuricum combined with 25 per cent calcium borogluconatum, 20 per cent magnesium gluconicum and Calcigluc, ie. magnesium-calcium compound containing chlorides and gluconates. The above preparations, depending on the mineral contents, were given in the form of intravenous infusions, subcutaneous or intramuscular injections at the rate commonly used or recommended. For the purposes of the examination, the samples of blood were taken before administering the preparations; at 15 min; then at 1, 2, 4, 8, 12, 24 and 48 hours. Comparative magnesium and calcic preparations curves indicated that magnesium gluconicum was more useful than magnesium sulfate. After the magnesium gluconicum infusion an increase of Mg level was observed which persisted in the blood for 12 hours. A similar prolonged effect could be achieved by means of magnesium sulfate given simultaneously i.v. and i.m. Recommended doses of 20% magnesium gluconate (0,5 ml per 1 kg of body weight) were relatively small and could be even doubled without any direct side effect. The addition of calcium sulfate to magnesium negatively influenced increase of Mg concentration in the serum, which makes the drug safer and enables the use of high doses, though we do not know much about its final biological effect.
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