Automation diagnostic methods and techniques of environmental monitoring combined with higher precision, sensitivity and selectivity of the currently available detection methods evokes a growing interest of medicine and medical diagnostics to produce the miniaturized diagnostic devices and technology which enable automation of medical procedures. Application of different sensors including chemical ones for detecting substance such as: peptides, proteins, ions, heavy metals in biological systems in which is low concentration of analyte is observed, forces us to use a miniaturized chemical nanosensors with high sensitivity and selectivity. This type of sensors are FET, ISFET and MOSFET. The nano-diagnostic devices with ability of molecular recognition that’s today's world most important analytical challenge for designers and chemists in order to obtain rapid and cheap diagnostic methods. In this paper we present the principle of FET and the genesis of the measuring system.
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