The article is an analysis of a performance of a swimmer who managed to win eight gold olympic medals in one tournament (China, 2008). The research has been conducted over anthropometrical, physiological, biochemical and psychological parameters of an athlete as well as his diet. Additionally, some attention was drawn to the training load, its changes, consequences and influence on the swimmer’s career.
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Tissue formation and maintenance is regulated by various factors, including biological, physiological and physical signals transmitted between cells as well as originating from cell-substrate interactions. In our study, the osteogenic potential of mesenchymal stromal/stem cells isolated from umbilical cord Wharton's jelly (UC-MSCs) was investigated in relation to the substrate rigidity on polyacrylamide hydrogel (PAAM). Osteogenic differentiation of UC-MSCs was enhanced on stiff substrate compared to soft substrates, illustrating that the mechanical environment can play a role in differentiation of this type of cells. These results show that substrate stiffness can regulate UC-MSCs differentiation, and hence may have significant implications for design of biomaterials with appropriate mechanical properties for regenerative medicine.
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