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1
The effect of pH on the interfacial tension of bilayer lipid membranes formed from phosphatidylcholine or phosphatidylserine
100%
Petelska A. D. , Naumowicz M. , Figaszewski Z. A.
Cellular and Molecular Biology Letters
|
2001
|
tom 06
|
nr 2A
419
2
The capacitance and resistance of the two-component bilayer lipid membrane modelling of the cell membrane
100%
Naumowicz M. , Petelska A. D. , Figaszewski Z. A.
Cellular and Molecular Biology Letters
|
2001
|
tom 06
|
nr 2A
414
3
Physicochemical analysis of phosphatidylcholine-ceramide system in bilayer lipid membranes
100%
Naumowicz M. , Petelska A. D. , Figaszewski Z. A.
Acta Biochimica Polonica
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2008
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tom 55
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nr 4
721-730
EN
Electrochemical impedance spectroscopy was used for the study of two-component lipid membranes. Phosphatidylcholine and ceramide were to be investigated, since they play an important biochemical role in cell membranes. The research on biolipid interaction was focused on quantitative description of processes that take part in a bilayer. Assumed models of interaction between amphiphilic molecules and the equilibria that take place there were described by mathematical equations for the studied system. The possibility of complex formation for two-component system forming bilayers was assumed that could explain the deviation from additivity rule. Equilibria were described by mathematical equations that were further verified experimentally. The determined values of parameters (stability constant, molecular area of complex, capacitance and conductance of the lipid membranes formed from molecules and complexes) were used for calculation of model curves. The comparison of model curves and experimental points verified the assumed model
4
The Equilibrium of Phosphatidylcholine-Sphingomyelin in a Monolayer at the Air/Water Interface
100%
Petelska A. D. , Naumowicz M. , Figaszewski Z. A.
Polish Journal of Chemistry
|
2008
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tom Vol. 82, nr 12
2323-2330
EN
Monolayers of either phosphatidylcholine (PC) or sphingomyelin (SM) or their mixtures (PC-SM) were investigated at the air/water interface. The surface tension values of pure and mixed monolayers were used to calculate the pi-A isotherms. The theory of equilibrium between components of monolayers at the air/water interface has been developed in order to obtain the stability constant of the PC-SM complex. We considered the equilibrium between PC, SM and the PC-SM complex on the basis of derived equations. We established that phosphatidylcholine and sphingomyelin formed a 1:1 complex, with the stability constant equal to KAB = 3.20x105 m2 mol-1.
5
The effect of the presence of crown ether on ion transport across the lipid bilayer
100%
Naumowicz M. , Petelska A. D. , Figaszewski Z. A.
Cellular and Molecular Biology Letters
|
2003
|
tom 08
|
nr 2
EN
We studied the electric properties of phosphatidylcholine bilayers modified with crown ether (dibenzo[18] crown-6). The studies were carried out for various crown ether concentrations in forming solutions and various potassium ion concentrations in electrolyte solutions. The presence of crown ether in the membrane influences the membrane's impedance; there is a reduction in its resistivity, a decrease in its resistance of phase transfer and an increase in its capacity of phase transfer with an increase in crown ether concentration in the bilayer and in K+ ion concentration in the electrolyte solution.
6
Capacitance and resistance of the bilayer lipid membrane formed of phosphatidylcholine and cholesterol
100%
Naumowicz M. , Petelska A. D. , Figaszewski Z. A.
Cellular and Molecular Biology Letters
|
2003
|
tom 08
|
nr 1
EN
Capacity and electric resistance of lipid membranes composed of lecithin and cholesterol were determined. The components were chosen for the study because they were present in biological membranes. Capacitance of the lecithin and cholesterol membranes amounts to 0.38 and 0.61 μF/cm2, and resistance to 1.44xl04 and 2.12x 106 Ω cm2, respectively. A 1:1 complex appears as a result of lecithin-cholesterol membrane formation. Parameters of the membrane formed of the lecithin-cholesterol complex were determined: surface concentration (Γ3), capacitance (C3), and conductance (R 31), as well as the stability constant (K) of the complex. The mean values of those magnitudes are as follows: 4.265xl0-6 mol/m2, 0.54 μF/cm2, 1.381xl0-6 Ω-1 cm-2 and 3.748x107, respectively.
7
Interfacial tension of the bilayer lipid membrane
100%
Petelska A. D. , Naumowicz M. , Figaszewski Z. A.
Cellular and Molecular Biology Letters
|
2002
|
tom 07
|
nr Suppl.
8
The effect of the presence of crown ether on ion transport across the lipid bilayer
100%
Naumowicz M. , Petelska A. D. , Figaszewski Z. A.
Cellular and Molecular Biology Letters
|
2002
|
tom 07
|
nr Suppl.
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