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EN
In the thesis the authors present complex results of the epidemiological study of oral health of the 6 - 12-year old schoolchildren attending elementary schools in Prešov (Slovakia) who participated in the Healthy Smile Prevention Project. The participants of the Project were represented by the pre-school children and schoolchildren from the age of 4 years attending the pre-school facilities and elementary schools and the project was performed by the dental hygienist, dental disease prevention officer, and school dental care assistant under supervision of a dental practitioner. The oral health of the abovementioned project participants was compared with the oral health of the group of children not participating in the prevention project. The project was supported by the Swiss company GABA.
EN
Objectives. The primary objective of the study was to test toothbrushes with different types of filaments (conical vs. rounded) with respect to cause gingival abrasion after surgical intervention of wisdom teeth. A secondary objective was to evaluate the efficacy of plaque removal and the improvement of gingival conditions to alleviate wound healing and to avoid gingivitis. Methods. One hundred and seventy-three healthy subjects with surgical intervention of wisdom teeth participated in a randomized, single blind study and were randomly allocated to control group (standard ADA reference toothbrush) or test group (meridol® special toothbrush with conical filaments). Clinical examinations included gingival abrasion, plaque index and gingival index, and were conducted at baseline, 7 and 28 days. Results. For the gingival abrasion the mean number of lesions of all sizes was after 28 days significantly lower in the test group (p-value <0.001) compared to control group. Plaque index was not significantly different between the two groups in the last visit. At day 28 the gingival index was significantly lower in the test group (p=0.031) compared to control group. Conclusions. The toothbrush with conical filaments induced significantly less gingival abrasions than the standard ADA toothbrush and showed superior results in improving gingival health (gingival index). Both toothbrushes were comparable effective with respect to plaque removal. Clinical Relevance. Scientific rationale for study: Supra and sub-gingival biofilm leads to gingival inflammation. Post-surgical removal of the biofilm from gingival surfaces promotes healing after wisdom tooth extraction. Tooth brushing leads to gingival abrasion. Earlier investigations with toothbrushes having conical filaments suggest less gingival tissue damage. Principal findings: The results showed that the toothbrush with conical filaments caused significantly less gingival abrasions than the toothbrush with rounded filaments. Practical implications: Toothbrush filament design should be considered when choosing toothbrush for oral hygiene after oral surgery.
PL
Przeprowadzono doświadczenie wazonowe z glebą (Haplic Phaeozem), do której dodawano wzrastające dawki kadmu (0 - 0,3 - 3,0 - 30,0 mg/kg), celem określenia ich wpływu na zawartość wtórnych metabolitów w koszyczkach rumianku (Matricaria recutita L. cv. Novbona). Dodatek kadmu do gleby powodował obniżenie zawartości olejku eterycznego w surowcu (Chamomillae anthodium) średnio o 10%, chamazulenu o 28% i (-)-α-bisabololu o 20%, a także akumulacji flawonu apigeniny i kumaryny herniaryny. Natomiast poziom (E)-β-farnezenu i en-in-dicykloeteru wzrastał w surowcu wraz ze wzrostem zawartości kadmu w glebie. Nie zaobserwowano toksycznego oddziaływania kadmu na rośliny podczas doświadczenia. Ponadto pierwiastek ten nie miał większego wpływu na plon surowca.
EN
A pot experiment with soil (Haplic Phaeozem) was conducted to observe the effect of increasing additions of Cd (0 - 0.3 - 3 - 30 mg. kg⁻¹ soil) on the content of some secondary metabolites in camomile anthodia (Matricaria recutita L.), cv. ‘Novbona’. The application of Cd into the soil resulted in a decreased content of essential oil (by 10% on average) in dry matter of the drug. The content of chamazulene in anthodia dry matter decreased by 28% and that of (-)-α-bisabolol by 20%. On the contrary, the level of (E)-β-farnesene and eneyne-dicycloethers increased with increasing level of Cd in the soil. On the other hand, soil Cd failed to affect accumulation of flavone apigenin and coumarin hemiarin in camomile anthodia. No visible symptoms of toxicity were observed on the plants during the experiment. Therefore, production of anthodium per plant was not influenced significantly by Cd addition to the soil.
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