Wyniki wyszukiwania - Biblioteka Nauki

1

The first detection of Echinococcus multilocularis DNA in water – an environmental survey conducted in the Warmia - Masuria province, north - eastern Poland

100%

Szostakowska B. , Lass A. , Pietkiewicz H. , Nahorski W. L. , Myjak P.

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nr Suppl.

2

Prevalence of anisakin nematodes in fish from Southern Baltic Sea

100%

Szostakowska B. , Myjak P. , Wyszynski M. , Pietkiewicz H. , Rokicki J.

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nr Suppl.

EN

Nematodes from the superfamily Ascaridoidea (families Anisakidae and Raphidascarididae) are worldwide distributed parasites. Their live cycles include many species of water invertebrates and teleostean fish as intermediate hosts, and fish, sea mammals or fish-eating birds being definitive hosts. Humans can be infected with some of these parasites after consumption of raw or wrongly processed fish. The parasitological investigations of fish (herring, cod and flatfish) from southern Baltic (ICES 24-26) provided in the years 80 and 90 showed their infection with larvae of several anisakid species: Anisakis simplex s. str., Contracaecum osculatum C and Hysterothylacium auctum. Sporadically Pseudoterranova decipiens and Raphidascaris acus were also found. Larvae of Anisakis simplex were noted mainly in herrings, C. osculatum primarily in cods and H. auctum in flounders. Additionally, preserved herrings (marinated, smoked) were also investigated and sporadically live larvae of A. simplex were found. The main etiological agent of human anisakidosis worldwide is A. simplex. Although the live cycle of this nematode cannot be completed in the Baltic Sea - this nematode is brought to the Baltic by infected herring migrating from the North Sea for spawning in coastal waters of the Southern Baltic - the prevalence and intensity of infection with larvae of this nematode species were the highest in fish investigated by us. The results obtained suggest the possibility of the human infection with A. simplex larvae in Poland.

3

Detection of molecular markers for chloroquine and pyrimethamine-sulfadoxine resistance in imported cases of Plasmodium falciparum malaria in Poland

100%

Myjak P. , Nahorski W. , Szostakowska B. , Zarnowska-Prymek H. , Pietkiewicz H.

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nr 3

EN

The identified mutations in the pfcrt, dhfr and dhps genes of Plasmodium falciparum show a very high correlation with resistance to chloroquine, pyrimethamine and sulfadoxine, the drugs that are still used as malaria chemoprophylaxis or treatment. We undertook a molecular screening of 82 Polish P. falciparum isolates, mainly imported from different countries of sub-Saharan Africa to assess their molecular drug-resistance profiles. Only 4 isolates showed no mutations in the three analyzed gene fragments. In the remaining isolates from one to six mutations in one or more examined genes were found. Different mutations in the pfcrt, dhfr and dhps genes were found in ca. 76%, 80% and 70% of P. falciparum isolates, respectively. About forty our patients used chloroquine or pyrimethamine + sulfadoxine as malaria chemoprophylaxis and/or antimalarial treatment, but without success. In all but 5 of the P. falciparum isolates obtained from these persons, mutations associated to resistance of the parasite to chloroquine and the antifolate drugs were found.

4

Lekoopornosc izolatow Plasmodium falciparum zawlekanych do Polski i uzyskanych od mieszkancow Angoli

86%

Myjak P. , Nahorski W. , Szostakowska B. , Pietkiewicz H. , Zarnowska-Prymek H. , Kryger T. , Wojtacha A.

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tom 53

10

5

Trudnosci diagnostyczno-terapeutyczne malarii w Polsce

86%

Nahorski W. L. , Goljan J. , Wroczynska A. , Kuna A. , Myjak P. , Pietkiewicz H.

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tom 53

168

6

Molecular differentiation of Entamoeba histolytica and Entamoeba dispar from stool and culture samples obtained from Polish citizens infected in Tropics and in Poland

86%

Myjak P. , Kur J. , Pietkiewicz H. , Kotlowski A. , Nahorski W. , Szostakowska B.

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nr 3

7

Standardy w zakresie laboratoryjnych czynności w parazytologii medycznej, oceny ich jakości i wartości diagnostycznej oraz laboratoryjnej interpretacji i autoryzacji wyników badań (propozycje)

58%

Myjak P. , Glowniak C. , Golab E. , Jaborowska-Jarmoluk M. , Kosik-Bogacka D. , Matowicka-Karna J. , Nowak P. , Pietkiewicz H. , Szostakowska B. , Wnukowska N. , Zarnowska-Pyrek H.

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tom 47

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nr 3