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1
Kalkulacje rolnicze. Kukurydza na ziarno
100%
Malek M.
Wieś Kujawsko-Pomorska. Ośrodek Doradztwa Rolniczego w Minikowie
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2019
|
nr 220
2
Kalkulacje rolnicze. Pszenica ozima
100%
Malek M.
Wieś Kujawsko-Pomorska. Ośrodek Doradztwa Rolniczego w Minikowie
|
2019
|
nr 217
3
Kalkulacje rolnicze. Cebula zwyczajna
100%
Malek M.
Wieś Kujawsko-Pomorska. Ośrodek Doradztwa Rolniczego w Minikowie
|
2015
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nr 169
4
Obowiązkowe ubezpieczenie budynków
100%
Malek M.
Wieś Kujawsko-Pomorska. Ośrodek Doradztwa Rolniczego w Minikowie
|
2019
|
nr 219
5
Zielone światło dla spółdzielczości rolniczej
100%
Malek M.
|
2018
|
nr 210
6
VAT a Fundusze Promocji
88%
Malek M.
|
|
nr 134
7
Tkactwo - zanikające rzemiosło
88%
Malek M.
|
2005
|
nr 51
8
Podatek rolny
75%
Malek M.
Wieś Kujawsko-Pomorska. Ośrodek Doradztwa Rolniczego w Minikowie
|
2010
|
nr 114
9
Wplyw metody konserwacji zielonek z traw z upraw na terenach ekologicznie zagrozonych na zawartosc pierwiastkow sladowych w uzyskanych paszach
63%
Pys J. B. , Malek M.
Acta Agraria et Silvestria. Series Zootechnica
|
2001-2002
|
tom 39-40
31-43
10
Lepsza fundacja czy stowarzyszenie?
51%
Sztandar-Sztanderska A. , Malek M.
|
|
nr 2
11
Udany debiut Bioplast Summit
50%
Malek M.
Opakowanie
|
2015
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nr 05
12
Koła jakości w SZPS "Otmęt" - Zakłady Obuwia w Prudniku
50%
Malek M.
Przegląd Skórzany
|
1988
|
tom 43
|
nr 04
13
Hyperbaric preconditioning combined with post-ischemic hyperbaric therapy prevents ischemia-evoked damage to CA1 hippocampal neurons of Mongolian gerbils
38%
Malek M. , Gamdzyk M. , Duszczyk M. , Ziembowicz A. , Sobczuk A. , Lazarewicz J. , Salinska E.
|
|
nr S
EN
Lack of the clinically effective pharmacological neuroprotection in different forms of brain ischemia increased the interest in alternative methods of therapy, like hypothermia or induction of brain tolerance by pre- and post-conditioning. The hyperbaric oxygen (HBO) therapy (2.5 atm) applied after ischemia or traumatic brain injury is one of the proposed but still controversial methods. The aim of this study was to find whether HBO and hyperbaric air (HBA) preconditioning followed by hyperbaric treatment applied for 60 min at different times after 3 min forebrain ischemia in gerbils will give a significant protection. The effects of both treatments on brain temperature and animal behaviour were also examined. A telemetric system to measure brain temperature was used and for behavioural observations a nest building test. The density of viable CA1 pyramidal neurons was also quantified. Our results show that HBO preconditioning combined with HBO postischemic therapy significantly reduced ischemia-evoked increase of brain temperature. HBA was also effective. Both treatments significantly increased gerbils’ ability to build a nest in comparison to untreated animals. The best effect was observed when postischemic therapy was applied 1 h after ischemia, but it was also effective 3 h after ischemia. Morphological analysis showed that HBO preconditioning combined with HBO postischemic treatment applied 1 h after ischemia significantly reduced neuronal damage in CA1 region of hippocampus resulting in 85% of surviving neurons compared to 18% of surviving CA1 neurons in the brains of animals subjected to ischemia but not treated with HBO. Our results show that HBO preconditioning combined with HBO therapy after forebrain ischemia in gerbils gives morphological protection which is accompanied by good behavioral results. Apart from inducing tolerance mediated by mild oxidative stress, HBO may affect blood oxygenation and other factors instrumental in brain protection.
14
Differential efficacy of mild normobaric hypoxia in inducing ischemic tolerance in two models of brain ischemia in vivo
38%
Duszczyk M. , Makarewicz D. , Malek M. , Ziembowicz A. , Lazarewicz J. , Salinska E.
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|
nr S
EN
Induction of short ischemic episodes after the stroke can be neuroprotective. Hypoxia was also suggested as the factor producing neuroprotection in the animal brain. Therefore in our studies we aimed to test if normobaric hypoxia (10% of oxygen) induced after ischemia could prevent neuronal loss. The model of hypoxia-ischemia (H-I) in 7-days old rats and the model of global forebrain ischemia in Mongolian gerbils were used. 7-days old rats were subjected to H-I and the first of three episodes of postconditioning hypoxia was induced 1, 3 or 6 hours after H-I episode. After ischemia gerbils were subjected to three trials of 1h hypoxia applied every 24 hours. The first episode was induced immediately, 2.5 h or 6 h after the ischemic insult. The morphological and behavioral effects of the postconditioning were evaluated. In the model of H-I on rats, the assessment of brain mass deficit revealed that normobaric hypoxia induced signifficant neuroprotection when applied 1 h or 6 h after H-I but not 2.5 h. In the global forebrain ischemia model normobaric hypoxia itself was harmless and the number of pyramidal neurons evaluated in CA1 region was the same as in the sham group. The neuroprotective effect of normobaric hypoxia postconditioning was observed when hypoxia was induced immediately after ischemia but not 2.5 or 6 hours after the insult. The behavioral evaluation showed only small improvement in nest-building test in postconditioned animals. Presented data show that normobaric hypoxia postconditioning produces the neuroprotective effect, however the therapeutic window of this treatment varies according to the model of brain ischemia. Supported by MSHE grant NN401003935.
15
Ocena gospodarki żelazem z wykorzystaniem rozpuszczalnego receptora transferyny
38%
Swiatkowska E. , Lukamowicz J. , Malek M. , Jander A. , Kowalska E. , Bartczak M.
|
2004
|
tom 40
|
nr 3
16
Treatment of multiple myeloma patients with autologous stem cell transplantation — a fresh analysis
32%
Wach M. , Cioch M. , Hus M. , Jawniak D. , Legiec W. , Malek M. , Manko J. , Walter-Croneck A. , Wasik-Szczepanek E. , Dmoszynska A.
|
|
nr 2
17
PCR-based diagnosis of Helicobacter pylori infection
32%
Klesiewicz K. , Karczewska E. , Sito E. , Malek M. , Wojcik M. , Marchewka M. , Lodygowska A. , Budak A.
Postępy Mikrobiologii. Suplement
|
2017
|
tom 56
|
nr 3
18
Obuwnictwo w II etapie reformy
32%
Malek M.
Przegląd Skórzany
|
1988
|
tom 43
|
nr 01
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