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EN
The Technical University of Liberec and Brandenburg University of Technology Cottbus-Senftenberg investigated the influence of cooling lubricants on the surface roughness and energy efficiency of cutting machine tools. After summarizing the achieved experimental results, the authors conclude that cooling lubricants extensively influence the cutting temperature, cutting forces and energy consumption. Also, it is recognizable that cooling lubricants affect the cutting tools lifetime and the workpiece surface quality as well. Furthermore, costs of these cooling lubricants and the related environmental burden need to be considered. A current trend is to reduce the amount of lubricants that are used, e.g., when the Minimum Quantity Lubrication (MQL) technique is applied. The lubricant or process liquid is thereby transported by the compressed air in the form of an aerosol to the contact area between the tool and workpiece. The cutting process was monitored during testing by the three following techniques: lubricant-free cutting, cutting with the use of a lubricant with the MQL technique, and only utilizing finish-turning and finish-face milling. The research allowed the authors to monitor the cutting power and mark the achieved surface quality in relation to the electrical power consumption of the cutting machine. In conclusions, the coherence between energy efficiency of the cutting machine and the workpiece surface quality regarding the used cooling lubricant is described.
PL
Gąbki przeznaczone dla inżynierii tkankowej wytworzone zostały z nowego terpolimeru glikolidu, L-laktydu i eta-kaprolaktonu, zsyntetyzowanego przy użyciu relatywnie niskotoksycznego acetyloacetonianu cyrkonu. Scharakteryzowano mikrostrukturę, porowatość i właściwości powierzchniowe otrzymanych gąbek. Gąbki miały pory o rozmiarze około 700 mikrom, nasiąkliwość 550% (+-40%) i porowatość 87% (+-1.2%). Degradację gąbek in vitro (w buforze fosforanowym) oceniano za pomocą SEM, FTIR i badań wiskozymetrycznych. Wykazano, że chociaż gąbki zaczynają ulegać degradacji natychmiast po kontakcie z buforem, zachowują one swoje wymiary i porowatą mikrostrukturę przez 5 tygodni in vitro.
EN
Foams intended for tissue engineering were produced from a new terpolymer of glycolide, L-lactide and etha-caprolactone, synthesized with the use of relatively low-toxic zirconium acetate. The microstructure, porosity and surface properties of the foams were characterized. The foams had the pore size of 700 microm, water uptake of 550% (+-40%) and porosity of 87% (+-1.2%). The degradation of foams in vitro (in PBS) was studied by SEM, FTIR and viscosity measurements. It was shown that the foams start to degrade immediately after contact with PBS, but they maintain they dimensions and porous microsctructure for 5 weeks in vitro.
3
Content available remote The study of the interactions between naproxen and N-acetyl-L-tyrosine ethyl ester
61%
EN
The interaction between naproxen and N-acetyl-L-tyrosine ethyl ester was investigated using UV-Vis absorption and fluorescence methods and the results indicate that an interaction is present in the ground state. Hydrogen bond formation between these two molecules in complexation was illustrated by the computer optimised complex. This theory was supported by the increased fluorescence lifetime decay observed, the Gibbs free energy for complexation and also by the geometry of the complex.
PL
W pracy zbadano oddziaływania pomiędzy naproxenem i N-acetylowym estrem etylowym L-tyrozyny metodami spektroskopii absorpcyjnej UV-Vis i fluorescencyjnymi. Wyniki wskazują na istnienie interakcji między cząsteczkami w stanie podstawowym. Powstawanie wiązania wodorowego pomiędzy tymi dwoma molekułami zobrazowane zostało poprzez komputerową optymalizację kompleksu. Teorię tą potwierdza wydłużenie czasu życia fluorescencji kompleksu, energia kompleksowania Gibbsa oraz geometria cząsteczki kompleksu.
EN
To study the pathogenesis of bovine spongiform encephalopathy infection in small ruminants, two Lacaune sheep with the AA136RR154QQ171 and one with the AA136RR154RR171 genotype for the prion protein, were inoculated with a brain homogenate from a French cattle BSE case by peripheral routes. Sheep with the ARQ/ARQ genotype are considered as susceptible to prion diseases contrary to those with the ARR/ARR genotype. The accumulation of disease-associated prion protein (PrP d) was analysed by biochemical and immunohistochemical methods. No PrP d accumulation was detected in samples from the ARR/ARR sheep 2 years post inoculation. In the two ARQ/ARQ sheep that had scrapie-like clinical symptoms, PrP d was found in the central, sympathetic and enteric nervous systems and in lymphoid organs. Remarkably, PrP d was also detected in some muscle types as well as in all peripheral nerves that had not been reported previously thus revealing a widespread distribution of BSE-associated PrP d in sheep tissues.
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