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We present a natural probabilistic variation of the multi-depot vehicle routing problem with pickup and delivery (MDVRPPD). In this paper, we present a variation of this deterministic problem, where each pair of pickup and delivery points are present with some probability, and their realization are only known after the routes are computed. We denote this stochastic version by S-MDVRPPD. One route for each depot must be computed satisfying precedence constraints, where each pickup point must appear before its delivery pair in the route. The objective is to find a solution with minimum expected traveling distance. We present a closed-form expression to compute the expected length of an a priori route under general probabilistic assumptions. To solve the S-MDVRPPD we propose an Iterated Local Search (ILS) that uses the Variable Neighborhood Descent (VND) as local search procedure. The proposed heuristic was compared with a Tabu Search (TS) algorithm based on a previous work. We evaluate the performance of these heuristics on a data set adapted from TSPLIB instances. The results show that the ILS proposed is efficient and effective to solve S-MDVRPPD.
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