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EN
This thesis presents a case study of an effective treatment of an indolent diabetic foot ulcer with the use of larvae of Lucilia sericata.The thesis draws the attention to the causes underlying the occurrence of diabetic foot and the influence of lower limb ischemia over the healing process of diabetic foot wounds and ulcers.The author of the thesis evaluates how implementing effective treatment influences the regression of infections within wounds and ulcers.
2
Content available remote Spontaneous Skin Fistula of the Lumbar Area - Case Report
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EN
Cutaneous fistulas of the lumbar area are rarely diagnosed. The presented case concerned a 46-year old female patient who underwent surgical treatment in 2008, at the Department of General and Bariatric Surgery, and Emergency Medicine. After twelve months of ineffective conservative therapy of a purulent cutaneous fistula the patient was directed to the Department of Surgery for radical excision of the lesion. After performing additional diagnostic examinations the patient underwent planned surgery, including the complete excision of the fistula canal, which had no contact with the peritoneal cavity. Numerous deposits were observed in the lumen of the fistula. Chemical analysis of the abovementioned demonstrated a 100% content of calcium oxalate, characteristic of urolithiasis. The patient was discharged from the hospital on the eighth day after the operation in good general condition, and with a properly healing wound. Both patient history and examination were unable to definitely determine the cause of the fistula.
EN
The aim of the study was an assessment of the early stage of felon - non exceeded 72 hours from the first symptoms - with 99mTc-MPD (metylendiphosphonien marked by Technetium) in relation to patient physical investigation and radiological hand investigation.Material and methods. 72 patients with the one finger felon were classified to the research. All patients were on the base of clinical investigations classified to the surgical intervention. Then they were divided on to two groups: one (A) where decision about final treatment method was based on 99mTc-MPD result. In the group X-ray was made also. The B group where the recognition verifying investigation was hand X-ray picture.Results. of investigations. In the A group on the basis of 99mTc-MPD to the surgical incision only 11 from 30 patients (36%) were classified. A pathological content was affirmed in 26% (at 8 patients). However in group B on the basis of X-ray examination only 5 patients (11%) from 42 were classify to surgical finger incision. Furthermore pathological content was affirmed in 14 patients (33%) after incision.Conclusion. In the early stage of finger felon the 99mTc-MPD investigation could be useful for verifying treatment method only.
4
Content available remote Endoscopic Treatment of obesity with an Intragastric balloon
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EN
The aim of the study was to evaluate the influence of vitamin E administered intraperitoneally on the prevention of peritoneal adhesion formation in rats on the basis of macroscopic and microscopic assessment of the adhesions.Material and methods. Experimental studies were performed on 50 Sprague-Dawley male rats, which were randomly divided into 5 groups, 10 rats in a group. Experimental group I (EI) included 10 rats which had peritoneal adhesions provoked by scraping of the wall of cecum and parietal peritoneum followed by intraperitoneal administration of vitamin E in the dose of 100 mg/kg body weight. Experimental group II (EII) included 10 rats which had peritoneal adhesions provoked by surgery, without administration of vitamin E. Control Group I (CI) included 10 rats which had the abdominal cavity opened without provoking peritoneal adhesions, and vitamin E was administered. Control Group II (CII) included 10 rats which had peritoneal adhesions provoked by surgery, and then lipid based solution was administered intraperitoneally. Control Group III (CIII) included 10 rats which had the abdominal cavity only opened and closed.Groups EI, CI and CII were the subject of the drugs intraperitoneal re-injection in first, second and third day after surgery. The animals were killed during the 8th postoperative day. Macroscopic examination of peritoneal adhesions using the classification reported by Nair was performed and samples for microscopic examination were excised.Results. In group EI peritoneal adhesions were formed in 60% rats (40% weak and 20% solid). In group EII peritoneal adhesions were found in all animals (30% weak and 70% solid). Reduction of the inflammatory response and less severe fibrosis were observed in animals with intraperitoneal administration of vitamin E.Conclusion. In the study, vitamin E administered intraperitoneally to rats decreased the intensity and extensiveness of peritoneal adhesions, which was confirmed by macroscopic and microscopic examinations.
EN
Anterior resection for rectal cancer carries the risk of serious complications, especially fistulas at the site of anastomosis. Numerous factors have been shown to impact anastomotic leakage. The results of studies on the influence of obesity on the frequency of anastomotic leakage after rectal resection performed due to cancer have been contradictory. The aim of the study was to evaluate the relationship between body mass index (BMI) and frequency of anastomotic leakage after anterior rectal resection performed due to cancer. Material and methods. This retrospective analysis included 222 subsequent patients who had undergone anterior resection due to cancer with an anastomosis formed with a mechanical suture. The patients were divided into 3 groups depending on their BMI quartile as follows: Group I, BMI < 23.8 kg/m2 (lower quartile); group II, BMI between 23.8 and 29.38 kg/m2 (middle quartile); and group III, BMI > 29.38 kg/m2 (upper quartile). Results. Anastomotic leakage occurred in 8 (3.6%) patients. Fistulas occurred in 4 out of 61 patients (6.56%) in group I, which was the highest incidence of fistulas for all 3 groups. In group II, fistulas occurred in 2 out of 55 patients (3.63%), and similarly, in group III, they occurred in 2 out of 106 patients (1.87%). The differences found in the frequency of fistulas between groups were not statistically significant (p=0.31). The logistic regression analysis did not show any relationship between leakage and age (p = 0.55; OR = 1.02; 95% CI: 0.95 - 1.1), sex (p = 0.97; OR = 0.97; 95% CI: 0.22 - 4.25) or BMI (p = 0.27; OR = 0.58; 95% CI: 0.22 - 1.53). Conclusions. The results of our study show that BMI did not have any influence on the frequency of anastomotic leakage after anterior rectal resection performed due to cancer.
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