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PL
Praca przedstawia analizę procesu planowania asortymentu w wielkopowierzchniowym przedsiębiorstwie handlu detalicznego. Przedstawiono tutaj poszczególne kroki postępowania przy planowaniu asortymentu oraz wskazano czynniki pływające na jego zakup.
EN
This paper presents an analysis of assortment planning process in a large-area retail enterprise. It resents various steps that are followed follow when planning the assortment and identifies the factors that influence its purchase.
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tom 65
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nr 10
723-726
EN
A premolar tooth reconstruction procedure was performed on a dog whose tooth was lost due to a trauma. After surgical removal of the tooth’s roots, a decision was made to reconstruct it with the use of a Titologic implant produced by Dentaurum. No complications occurred during either the implantation procedure or the subsequent healing period. Except for the shortened healing period resulting from the much faster tissue regeneration in dogs the procedures employed reflected those typical for the treatment of humans. The article presents the early post-procedure examination results as well as the clinical condition after a six month observation period. During control visits no symptoms of periimplantitis were observed that would indicate complications resulting from faulty implantation, bone overheating, inadequate implant loading, or the lack of or insufficient hygienic regimen.
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EN
The aim of this study was to determine the vascularisation level in malignant tumours of the oral cavity. The studied material comprised 10 samples of neoplastic tissue extracted from dogs with a suspicion of oral cavity carcinoma. The samples were collected from nine male and one female dogs of various breeds, aged between 6 and 16 years. The tumours were located within the areas of mandibular and maxillary gingiva. Tumour specimens were preserved in 10% buffered formalin for 24 h, embedded in paraffin, and then sections stained with haematoxylin and eosin were prepared. Tumour type was diagnosed according to the official WHO classification. In order to render the vascular endothelium visible, immunohistochemical staining was performed with the use of the polyclonal antibody against von Willebrand factor F VIII and DAKO EnVision system. In the quantitative analysis of the blood vessels displaying the FVIII factor expansion, a system of computer-assisted microscopic analysis was utilised. In ten microscopic fields the vessels were counted and a mean value per 1 mm² was calculated. The largest numbers of blood vessels were observed in squamous cell carcinomas. In the remaining tumours, the vessel count fluctuated between 78-97/mm² (mean 87). The conducted research indicated that angiogenesis in malignant tumours of the oral cavity has potential diagnostic application in determining the malignancy levels of neoplasms.
EN
The occurrence of intestinal tumors is relatively seldom. The article describes a case of a dog’s ileal neoplasia. Symptoms like persistent diarrheas, significant body loss and reduced mobility occurred. Radiography of the abdomen revealed a tumor of 10 cm in diameter located in the left subcostal area. Blood results showed leukocytosis and an elevated activity of alkaline phosphatase. The tumor was removed during laparotomy, and a part of the jejunum was resected. Histopathology showed the presence of T-cell lymphosarcoma. The patient’s health deterioration came 4 months after the surgery. Repeated radiography and ultrasonography revealed secondary cancers in different organs. The dog was euthanased. Necropsy confirmed metastases in intestines, lungs, liver, and kidneys. Therapeutic procedures on malicious tumors of alimentary tract, including this case of ileal lymphosarcoma, are described.
EN
The presence of pamidronate during local use of bisphosphonates (BP)-enriched bone cement was determined. The question was whether pamidronate implanted into the bone cement is eluted. The study was performed on 10 probes of BP-enriched bone cement located in 0.9% NaCl. The probes were incubated for 3 and 6 weeks. Ion-pair HPLC was used for the detection of pamidronate. Then, capillary electrophoresis was applied for quantitative analysis of pamidronate in the 3rd and 6th week after incubation. The presence of pamidronate, eluted from BP-enriched bone cement into 0.9% NaCl solution 3 and 6 weeks after incubation, was demonstrated. These results may explain the changes in the level of cytokine RANKL and bone turnover marker osteoprotegrin in rats' serum treated with BP-enriched bone cement 3 and 6 weeks after surgery. The possibility of effective local use of BP-enriched bone cement in veterinary medicine was underlined. The results, and the former conducted research, point out that the clinical applications of BP-enriched bone cement in vivo may have some validity in the future.
PL
W eksperymencie in vivo zbadano podstawowe cechy dwufazowego kompozytu kościozastępczego tj. biozgodność i osteokonduktywność, a także jego właściwości osteoindukcyjne. Testowany kompozyt, przeznaczony do wypełniania ubytków kostnych, został wykonany z granul hydroksyapatytu węglanowego i polimeru polisacharydowego. Biomateriał został wszczepiony do kości piszczelowych królików na okres 1 lub 3 miesięcy. Po tym czasie zbadano stopień regeneracji kości na podstawie badań makroskopowych (radiologicznych) i mikroskopowych. Stwierdzono zaawansowane procesy osteointegracji i przebudowy kostnej w okolicy implantu, co wskazuje zarówno na osteokonduktywne, jak i osteoindukcyjne właściwości badanego biomateriału.
EN
Basic characteristics of a hydroxyapatite-glucan biomaterial such as biocompatibility, osteoconductivity and osteoinductive properties were tested in in vivo experiment. The two-phase composite, intended for filling bone defects, was made of carbonated hydroxyapatite granules and polysaccharide polymer. The biomaterial was implanted to the tibial metaphysis in rabbits for the 1- or 3-month period. Bone regeneration after that time was evaluated by radiology and histology. Our analysis showed advanced osseointegration and extensive bone remodelling in the direct vicinity of implants indicating osteoinductive and osteoconductive properties of the material studied.
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