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Content available remote Microdialysis technique in monitoring of the patient's metabolic state
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EN
Frequent daily monitoring of the blood glucose level is not an adequately efficient method to maintain long-term normoglycemia and especially to prevent hypoglycemia in many diabetic patients. Continuous glucose measurement systems are currently being developed. The minimally invasive methods are mainly connected with measurements in the interstitial fluid (ISF). With the electroenzymaitic sensor implanted, the ISF glucose continuously reacts with the sensor’s enzyme, and the resulting current is proportional to the glucose concentration. Another possibility can be application of the microdialysis technique (MDS) - technique to monitor the biochemistry of the extracellular space in living tissue. The aim of the study was to review systems for continuous glucose measurements using the microdialysis technique and to present preliminary results of an application of this technique to monitoring of the patient’s metabolic state in ketoacidosis. The first prototype of a system for continuous glucose measurements,was designed and developed in Ulm. Currently, a few similar systems with application of the microdialysis are being developed and tested. The most interesting of them are Accu Chek (Roche Diagnostics), GlucoDay (Menarini) and Gluc-Online (Roche/Disetronic). The MDS technique can be applied, for example, to characterize the patient’s metabolic state in ketoacidosis during application of the standard treatment by measurements of the biochemical parameters, like glucose, lactate and glycerol, in the interstitial fluid. This study was performed by the authors in cooperation with the Clinic of Gastroeneterology and Metabolic Diseases, Medical University in Warsaw. The first presented results indicate that, after the initial hydration, the glycemia, glycerol and lactate levels correlated in a very different way with the reference measurements from blood. No distinct delays between the measurements performed in the studied compartments were observed. It can be stated that the analysis of the courses of the biochemical compounds, involved in the glucose metabolism, in the interstitial and in the blood compartments may be helpful to better understand the pathophysiology of the diabetic ketoacidosis, and consequently, its application can lead to an improvement of the current standard treatment.
EN
In this work a hybrid material containing iron oxide was used as an effective sorbent for removal of Cr(VI) from water solutions. The hybrid sorbent was obtained by new method using redox S/DVB copolymer containing N-chlorosulfonamide functional groups in reduction/oxidation reaction with Fe(II) ions. The obtained product contained sulfonamide functional groups which are not charged in wide pH range (till pH = 11.0), what differs our product from other polymeric hybrid sorbents with iron oxide reported in the literature and obtained on the basis of ion exchangers. The sorption kinetic data were well described by pseudo-second order model indicating the chemisorption of chromate onto iron oxide surface. These data also correlated well with intraparticle diffusion model, what showed that diffusion within the polymer structure was the rate determining step of the chromate sorption process. The equilibrium studies showed that removal of Cr(VI) was pH dependent and was favored under acidic conditions (pH = 2.5—5.0). After adsorption process chromates were effectively desorbed from the adsorbent surface by NaOH solution.
PL
W pracy przedstawiono wyniki badań sorpcji jonów Cr(VI) przy użyciu zsyntezowanego polimeru hybrydowego zawierającego tlenki żelaza. Hybrydowy sorbent otrzymano w wyniku reakcji utleniania jonów Fe(II) z wykorzystaniem makroporowatego, redoksowego polimeru S/DVB z N-chlorosulfonamidowymi grupami funkcyjnymi w formie Na+. Uzyskany produkt zawiera sulfonamidowe grupy funkcyjne charakteryzujące się wysokim pKa = 11, dzięki czemu nie wykazuje on właściwości jonowymiennych, a jedynie sorpcyjne (w odróżnieniu od opisanych w literaturze polimerów hybrydowych otrzymywanych z wykorzystaniem wymieniaczy jonowych). Badano sorpcję z roztworów Cr(VI), o stężeniach od 5 do 100 mg Cr(VI)/dm3 i o różnym pH, od 2,5 do 11,0 a także w obecności innych jonów: Cl- (500 mg/dm3) i SO42- (1000 mg/dm3). Badania kinetyczne wykazały, że sorpcja chromianów przebiega zgodnie z modelem chemicznym (pseudo-second order model) (rys. 1), co dowodzi chemisorpcji chromianów na powierzchni tlenków żelaza. Z kolei, dobre dopasowanie danych eksperymentalnych do modelu dyfuzyjnego (intraparticle diffusion model) wskazuje, że czynnikiem determinującym szybkość procesu jest dyfuzja chromianów w głąb struktury ziarna polimeru (rys. 2). Wykazano również, że sorpcja chromianów jest zależna od pH roztworu i przebiega najbardziej efektywnie w środowisku kwasowym (pH = 2,5—5,0) (rys. 3). Przemywanie zużytego złoża hybrydowego polimeru roztworem 0,1 M NaOH, pozwoliło na zdesorbowanie 93 % jonów Cr(VI).
EN
We have obtained deep near infrared J- and K-band observations of 14 BL Her and 5 W Vir SMC stars from the OGLE-III survey with the ESO New Technology Telescope equipped with the SOFI infrared camera. From these observations, period-luminosity (P-L) relations in the J and Ks 2MASS bands were derived. The slopes of the K- and J-band relations of -2.15±0.19 and -1.95±0.24, respectively, agree very well with the corresponding slopes derived previously for population II Cepheids in globular clusters, Galactic bulge and in the Large Magellanic Cloud. The distance modulus to the SMC obtained from our data using P-L relation derived for globular cluster Cepheids equals to 18.85±0.07 (statistical) ± 0.07 mag (systematic without including potential metallicity effect), which within the uncertainties agrees well with the results obtained with other methods.
EN
We present the results of a search for variable stars in the field of NGC 6259. Altogether 85 variable stars have been discovered. 36 of them are eclipsing systems. This group contains 13 EA, 2 EB and 21 EW-type stars. Light curves of two variable stars resemble those of Miras. The remaining 47 variable stars detected in the field of this open cluster are most probably highly obscured red giants (OSARG, irregular). For all detected variable stars we provide their light curves, preliminary classification, discussion on the possible cluster membership, equatorial coordinates, finding charts and periods when possible.
EN
We present the results from a search for variable stars in the field of a young open cluster NGC 6755. Altogether seventy one variable stars have been discovered. Thirty one of them are eclipsing systems. This group contains ten EA, four EB and seventeen EW-type systems. Photometric variability of four late type stars is most probably caused by their chromospherical activity. Another seven detected variable stars have light curves typical for pulsating stars from the main instability strip. Four of them we tentatively classified as γ Dor, one as δ Sct and two as Population II Cepheid variable stars, respectively. Star designated as V40 can be either another population II Cepheid or an ellipsoidal binary system. The remaining twenty eight variable stars found in the field of this open cluster are most probably highly obscured background red giants (OSARG, irregular). For all detected variable stars we provide their light curves, preliminary classification, discussion on the possible cluster membership, equatorial coordinates, finding charts and periods when possible.
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EN
The aim of the present study was to verify a system for continuous monitoring of feet temperature. The temperature measurement system developed in cooperation of the Center for Biomedical Technology (Krems, Austria) and Digilog Inc. (Perg, Austria) company was used for monitoring of the skin temperature on foot. The temperature monitoring devices are wirelessly controlled and they could be encapsulated in order to achieve waterproofing and facilitate disinfection with liquid disinfectant. The skin temperature measurements were performed every 1 or 5 minutes. Two healthy subjects were monitored for 7-9 days. The preliminary system application showed its usefulness in continuous temperature monitoring of feet.
9
Content available remote Comparison of the wound area assessment methods in the diabetic foot syndrome
26%
EN
The paper presents results of comparison of the wound area assessment methods in the diabetic foot syndrome (DFS). Wound size is a basic parameter that is used to evaluate efficacy of the applied treatment. Four measurement methods were used: the rulers, the planimetric Visitrak (Smith & Nephew, England), the Silhouette (Aranz Medical, New Zealand) applying lasers, digital photography and planimetry as well as the patient's module of TeleDiaFoS telecare system with the foot scanning capabilities. Study group consisted of 18 DFS patients. Nineteen wounds were successfully measured with all 4 methods. The results of the Visitrak and the Silhouette can be used interehangeably (r = 0.994, slope = 1.01, intercept = 0.154 cm2). For the other systems strong linear relationships exist that can be used to convert the wound area measured with one method to the corresponding value of another method. The correlation coefficients higher than 0.985 were obtained in ease of 3 systems: Visitrak, Silhouette and TeleDiaFoS. The TeleDiaFoS system can provide a physician with the patient-self-taken wound images that can be used for reliable assessment of the wound healing process during home tele-monitoring of the DFS patients.
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