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On the way to understand biological complexity in plants: S-nutrition as a case study for systems biology

100%

Hesse H. , Hoefgen R.

tom 11

nr 1

The establishment of technologies for high-throughput DNA sequencing (genomics), gene expression (transcriptomics), metabolite and ion analysis (metabolomics/ionomics) and protein analysis (proteomics) carries with it the challenge of processing and interpreting the accumulating data sets. Publicly accessible databases and newly development and adapted bioinformatic tools are employed to mine this data in order to filter relevant correlations and create models describing physiological states. These data allow the reconstruction of networks of interactions of the various cellular components as enzyme activities and complexes, gene expression, metabolite pools or pathway flux modes. Especially when merging information from transcriptomics, metabolomics and proteomics into consistent models, it will be possible to describe and predict the behaviour of biological systems, for example with respect to endogenous or environmental changes. However, to capture the interactions of network elements requires measurements under a variety of conditions to generate or refine existing models. The ultimate goal of systems biology is to understand the molecular principles governing plant responses and consistently explain plant physiology.

Theoretical analysis of chemical bonding behaviors and dielectric properties of different phases of ice

80%

Xue D. , Betzler K. , Hesse H. , Ratajczak H.

Bulletin of the Polish Academy of Sciences. Chemistry

2001

tom Vol. 49, No. 4

289-298

From the chemical bond viewpoint, the chemical bond parameters, linear optical properties and geometrical characteristics of constituent chemical bonds (i.e., O-H and H.. .O bonds) in the single-crystalline ice phases I, II, III, VI, VII and VIII have been quantitatively studied. At the same time, the chemical bonding situations of constituent H(D) atoms in different phases of ice have been numerically scaled. The calculated results show that the different lengths and directions of the hydrogen bonding O-H(D).. .O (including two parts: H(D)-O and H(D).. .O bonds) in the different phases of ice cause a large variation in the linear optical properties. Their characteristics found in single-crystalline phases of ice can be used as a guideline for the application of this special kind of functional chemical bond as linkage in materials design.