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1
Rola markerow nowotworowych w diagnostyce i monitorowaniu nowotworow
100%
Badowska-Kozakiewicz A. , Malicka E.
Życie Weterynaryjne
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2008
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tom 83
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nr 03
210-213
2
Nowotwory ukladu pokarmowego psow i kotow. Retrospektywny przeglad 87 przypadkow
80%
Sapierzynski R. , Badowska-Kozakiewicz A. , Malicka E.
Medycyna Weterynaryjna
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2008
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tom 64
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nr 10
1213-1217
EN
The aim of the study was to estimate the prevalence and localization of different types of gastrointestinal tumors in dogs and cats in relation to sex, age and breed of the animals. The study was performed on tissue specimens of gastric, intestinal, salivary gland, liver and pancreas obtained during surgery from dogs and cats submitted to the Division of Pathological Anatomy, Department of Clinical Sciences at the Agricultural University of Warsaw from 1996 to 2006. During this period 73 canine tumors and 14 feline tumors were recognized. In cats most tumors (92.8 % of the cases) were malignant, the most common were adenocarcinomas, rarely sarcomas and lymphomas. The tumors were localized mainly in the small intestine, liver and pancreas, large bowel tumors were not observed. The median age of affected cats was slightly more than 9 years, most of animals were male. Gastric and intestinal tumors in dogs were recorded in animals from 9 months to 14-years-of-age, more common in males. The tumors were most commonly derived from the large intestine, especially from the rectum; however the median age of dogs with lesions was lower than in animals in which neoplasms were present in other parts of the gastrointestinal tract. Of interest was the phenomenon that liver tumors, especially hemangiosarcoma, were often recognized in German shepherd dogs.
3
Rak zapalny - rzadki przypadek nowotworu gruczołu sutkowego u psów
80%
Badowska-Kozakiewicz A. , Malicka E. , Sobczak-Filipiak M.
Życie Weterynaryjne
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2008
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tom 83
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nr 12
4
Content available Influence of Lead and Cadmium Ions on the Entomopathogenic Nematodes Steinernema feltiae Filipjev
80%
Kamionek M. , Jarmuł-Pietraszczyk J. , Badowska-Kozakiewicz A. , Pezowicz E.
Ecological Chemistry and Engineering. A
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2011
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tom Vol. 18, nr 3
365-369
EN
The aim of this study was to determine the influence of lead and cadmium compounds on the entomopathogenic nematodes Steinernema feltiae Filipjev. The conducted research allowed to determine the sexual strucure of the nematodes developing inside the body cavity of the host as well as the survival rate of IJs before leaving the insect and after the migration to the external environment. Chemical and biological material as used in the conducted experiments. Chemical material included lead nitrate at the concentration of 40,100,500 ppm and cadmium nitrate at the concentration of 1, 2, 3 ppm. Biological material included the entomopathogenic nematodes Steinernema feltiae and test insects – Galleria mellonella L. – larvae from own culture.
PL
Celem pracy było określenie wpływu związków ołowiu i kadmu na nicienie entomopatogenne Steinernema feltiae Filipjev. Prowadzone badania umożliwiły określenie struktury płciowej nicieni rozwijających się w jamie ciała żywiciela, jak również przeżywalność IJs przed opuszczeniem owada oraz po migracji do środowiska zewnętrznego. W prowadzonych badaniach użyto materiału biologicznego i chemicznego. Materiał chemiczny stanowił azotan ołowiu w stężeniach 40 100 500 ppm oraz azotan kadmu w stężeniach 1, 2, 3 ppm. Materiał biologiczny stanowiły nicienie entomopatogenne Steinernema feltiae i owady testowe – larwy Galleria mellonella L. – hodowla własna.
5
Retrospektywna ocena badan histopatologicznych nowotworow kosci u psow w latach 1996-2006
80%
Badowska-Kozakiewicz A. , Sapierzynski R. , Bielecki W.
Życie Weterynaryjne
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2007
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tom 82
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nr 10
828-831
6
Content available Immunohistochemical evaluation of expression of heat shock proteins HSP70 and HSP90 in mammary gland neoplasms in bitches
80%
Badowska-Kozakiewicz A. , Malicka E.
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nr 2
7
Content available remote Comparison of cellular and tissue transcriptional profiles in canine mammary tumor
61%
Pawlowski K. M. , Krol M. , Majewska A. , Badowska-Kozakiewicz A. , Mol J. A. , Malicka E. , Motyl T.
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tom 60
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nr 1
85-94
EN
Tumor-derived cell lines are widely used as in vitro cancer models. Cell lines historically served as the primary experimental model systems for exploration of tumor cell biology and pharmacology. However, their ability to accurately reflect the phenotype and genotype of the parental histology remains questionable, given the prevalence of documented cell line-specific cytogenetic changes. Sometimes cell line studies are interpreted in the context of artifacts introduced by selection and establishment of cell lines in vitro. This complication has led to difficulties in the extrapolation of biology observed in cell lines to tumor biology in vivo. The aim of our study was to compare gene expression profiles in canine mammary tumor tissue and cell cultures derived from those tumors using cDNA microarrays. Tumors of two different origins were used; chondrosarcoma and adenocarcinoma and their primary cell cultures. It has been found that cell culture gene expression profiles closely resembled those of their corresponding in vivo tumor. In adenocarcinoma and chondrosarcoma only 6.0% and 2.7% of genes respectively, have shown significant difference in expression. In the most cases the difference concerned up-regulation of gene expression in cell lines, particularly genes involved in: protein metabolism and modification, signal transduction and nucleotide, nucleoside and nucleic acid metabolism. These experiments revealed that transcriptome of our primary cell culture corresponds to transcriptome of its parental tumor tissue and for this reason cell culture represents the reliable in vitro model for oncogenomic and pharmacogenomic studies.
8
Retrospektywna ocena wystepowania nowotworow gruczolu mlekowego u psow w latach 1996-2006
61%
Badowska-Kozakiewicz A. , Dolka I. , Malicka E. , Rodo A. , Skrzypczak M. , Sobczak-Filipiak M.
Życie Weterynaryjne
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2007
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tom 82
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nr 06
472-476
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