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2 Central European Journal of Sport Sciences and Medicine
1 Baltic Journal of Health and Physical Activity. The Journal of Gdansk University of Physical Education and Sport
1 Zeszyty Naukowe. Prace Instytutu Kultury Fizycznej. Uniwersytet Szczeciński

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Association of the ACTN3 R577X polymorphism in Polish rowers

100%

Jastrzebski Z. , Leonska-Duniec A. , Kolbowicz M. , Tomiak T.

tom 06

nr 3

Background: The ACTN3 R577X polymorphism has been associated with an elite athlete status. Several studies have determined that the R allele is connected with power-oriented athletic performance, whereas the nonfunctional XX genotype may give some beneficial effect for endurance performance. The main aim of the study was to determine the possible interaction between the ACTN3 R577X polymorphism and an endurance athlete status in a group of Polish rowers in comparison with sedentary individuals. Material/Methods: 121 male Polish rowers, members of academic sports clubs, and 115 unrelated volunteers were recruited for the study. Genotyping for the R577X variant was performed by PCR–RFLP. Results: The genotype distribution amongst the rowers (52.06% RR, 38.85% RX, 9.09% XX) was significantly different from that amongst sedentary individuals (RR-33.5%; RX- 49.60%; XX-17,35%; P = 0.024). A significant excess of the R allele was noted in the rowers (71.48%, P = 0.008) when comparing with the controls (60.0%). Conclusions: The obtained results show that the ACTN3 X allele and XX genotype are underrepresented in Polish rowers and they are not advantageous for the endurance-type athletes in the studied population. On the contrary, the R allele seems to be useful for a top-level rower. However, additional studies are needed to clarify this problem.

Selected nutritional behaviors and the level of physical activity of high school students

100%

Ratajczak J. , Rucinska K. , Kolbowicz M. , Zalewski T.

nr 3

The angiotensin converting enzyme gene I/D polymorphism in Polish rowers

100%

Jastrzebski Z. , Leonska-Duniec A. , Kolbowicz M. , Tomiak T.

tom 05

nr 1

Angiotensin converting enzyme gene (ACE) is the most frequently investigated genetic marker in the context of genetic conditioning of athletic predispositions. The product of the gene is a key component of the renin-angiotensin system (RAS) and the kallikrein-kinin system (KKS), mainly responsible for the regulation of blood pressure. The main aim of the study was to determine the possible interaction between the ACE l/D polymorphism and endurance athlete status in a group of Polish rowers in comparison with sedentary individuals. 121 male Polish rowers, members of academic sports clubs, and 115 unrelated volunteers, were recruited for the study. The PCR amplification of the insertion (I) or deletion (D) fragment of the ACEgene was performed. Compared with control group, the frequency of the I allele differ significantly from that found in rowers (57.4% vs. 44.3%; P = 0.013) and the ACE genotype frequency amongst the whole cohort of rowers (30.6% II, 53.7% ID, 15.7% DD) was also different from expected values (control group 19.1% II, 50.4% ID, 30.4% DD; P=0.017). Our investigation confirms a positive association of the I allele of the ACE gene with endurance athlete status in a group of Polish rowers.

Genetyka w sporcie wyczynowym - rola i znaczenie poszczególnych form polimorficznych genu ACE u wioślarzy o wysokich kwalifikacjach

75%

Cieszczyk P. , Krupecki K. , Maciejewska A. , Sawczuk M. , Leonska-Duniec A. , Kolbowicz M.

nr 27