Platelet rich plasma (PRP) is an ortobiological material, which is gaining popularity in the treatment, regeneration and acceleration of tissue healing. The article contains extensive information about the nature, mechanism of action, therapeutic properties and application of autologous platelet rich plasma (PRP) in medicine. The authors describe the technology of the acquisition and the effects of the PRP injection site, its beneficial effects on the regeneration of collagen, wound healing and reconstruction operations involving transplants.