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EN
The aim of the study was to determine the interrelationships between densitometric, morphometric, and mechanical properties of the femur in 5 month old Polish Merino sheep. The study was performed on 24 healthy male lambs at the age of 5 months. All right femora were weighed and their length was measured. Using QCT technique, the determination of volumetric bone mineral density (vBMD) of the trabecular and cortical bone compartments was performed. Total bone volume and mean volumetric bone mineral density of whole femur were also determined. Geometrical properties such as cross-sectional area, second moment of inertia, mean relative wall thickness, and cortical index were calculated on the basis of computed tomography measurements. Mechanical properties of the femur in terms of maximum elastic strength (Wy) and ultimate strength (Wf) were determined using a three-point bending test. Furthermore, Pearson's correlation coefficient was determined for all the investigated variables of the femur. Obtained results have shown significant correlations between morphometric, densitometric, and mechanical parameters of the femur. Statistically significant correlations between vBMD of cortical bone and Wy (r = 0.61) and Wf (r = 0.57) indicate the highest value of this densitometric parameter for mechanical strength prediction of bones in vivo. Thus, computed tomography technique may serve in sheep as non-invasive and precise tool for in vivo monitoring of metabolic responses of skeleton, in terms of morphological and densitometric properties, to physiological, metabolic, nutritional, pharmacological, and toxicological factors influencing bone tissue metabolism.
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