Wyniki wyszukiwania - Biblioteka Nauki

1

Genetyczna regulacja metabolizmu w drożdżach Saccharomyces cerevisiae

100%

Rytka J.

Postępy Biochemii

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1978

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tom 24

|

nr 2

2

Genetyka i biogeneza mitochondriów Saccharomyces cerevisiae

100%

Rytka J.

Postępy Mikrobiologii

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1978

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tom 17

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nr 3-4

3

Drozdze modelowym organizmem eukariotycznym w biologii molekularnej

63%

Rytka J. , Palamarczyk G.

Postępy Biochemii

|

1993

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tom 39

|

nr 3

152-155

4

Genetyka i biogeneza mitochondriów Saccharomyces cerevisiae

63%

Rytka J. , Putrament A.

Postępy Mikrobiologii

|

1978

|

tom 17

|

nr 3-4

5

Allosteryczna kontrola aktywności biologicznej niektórych białek

63%

Grzelakowska-Sztabert B. , Rytka J.

Postępy Biochemii

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1968

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tom 14

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nr 2

6

Isolation and properties of D-lactate dehydrogenase from yeast grown anaerobically

63%

Rytka J. , Tysarowski W.

Acta Biochimica Polonica

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1965

|

tom 12

|

nr 3

7

Metody badania struktury centum aktywnego enzymów

63%

Palamarczyk G. , Rytka J.

Postępy Biochemii

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1970

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tom 16

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nr 2

8

Drogi przemian metyloglioksalu w organizmach żywych

63%

Konecka A. M. , Rytka J.

Postępy Biochemii

|

1970

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tom 16

|

nr 4

9

Drozdze Saccharomyces cerevisiae modelowym organizmem w badaniach nad fototoksycznym dzialaniem porfiryn

63%

Zoladek T. , Rytka J.

Działalność Naukowa PAN. Wybrane Zagadnienia

|

1998

|

tom 05

71-72

10

Biosynteza hemu w drozdzach Saccharomyces cerevisiae

63%

Chelstowska A. , Rytka J.

Postępy Biochemii

|

1993

|

tom 39

|

nr 3

173-185

11

Saccharomyces cerevisiae as a model organism for studying function and biogenesis of peroxisomes

63%

Skoneczny M. , Rytka J.

Acta Microbiologica Polonica

|

1995

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tom 44

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nr 3-4

12

Saccharomyces cerevisiae - a model organism for the studies on vacuolar transport

63%

Kucharczyk R. , Rytka J.

Acta Biochimica Polonica

|

2001

|

tom 48

|

nr 4

EN

The role of the yeast vacuole, a functional analogue of the mammalian lysosome, in the turnover of proteins and organelles has been well documented. This review provides an overview of the current knowledge of vesicle mediated vacuolar transport in the yeast Saccharomyces cerevisiae cells. Due to the conservation of the molecular transport machinery S. cerevisiae has become an important model system of vacuolar trafficking because of the facile application of genetics, molecular biology and biochemistry.

13

Ribosome biogenesis and nucleolar function in yeast Saccharomyces cerevisiae

63%

Gromadka R. , Rytka J.

Cellular and Molecular Biology Letters

|

2000

|

tom 05

|

nr 2

EN

This review provides an overview of the current knowledge of ribosome biogenesis, nucleolus structure and function and protein traffic into and out of the nucleus, with emphasis on the potential of yeast Saccharomyces cerevisiae as a model organism.

14

The KRR1 gene encodes a protein required for 18S rRNA synthesis and 40S ribosomal subunit assembly in Saccharomyces cerevisiae

63%

Gromadka R. , Rytka J.

Acta Biochimica Polonica

|

2000

|

tom 47

|

nr 4

EN

The newly discovered Saccharomyces cerevisiae gene KRR1 (YCL059c) encodes a protein essential for cell viability. Krr1p contains a motif of clustered basic amino acids highly conserved in the evolutionarly distant species from yeast to human. We demonstrate that Krr1p is localized in the nucleolus. The KRR1 gene is highly expressed in dividing cells and its expression ceases almost completely when cells enter the stationary phase. In vivo depletion of Krr1p leads to drastic reduction of 40S ribosomal subunits due to defective 18S rRNA synthesis. We propose that Krr1p is required for proper processing of pre-rRNA and the assembly of preribosomal 40S subunits.

15

Hemoprotein formation in yeast. VI. Mutants with changed level of catalase and of other heme enzymes under conditions of glucose repression

51%

Bilinski T. , Sledziewski A. , Rytka J.

Acta Microbiologica Polonica

|

1980

|

tom 29

|

nr 3

16

Hemoprotein formation in yeast. VII. Genetic analysis of pleiotropic mutants affected in the response to glucose repression and anoxia

51%

Bilinski T. , Litwinska J. , Sledziewski A. , Rytka J.

Acta Microbiologica Polonica

|

1980

|

tom 29

|

nr 3

17

Regulation of sporulation in the yeast Saccharomyces cerevisiae

51%

Piekarska I. , Rytka J. , Rempola B.

Acta Biochimica Polonica

|

2010

|

tom 57

|

nr 3

EN

Sporulation of the budding yeast Saccharomyces cerevisiae - equivalent to gametogenesis in higher organisms, is a complex differentiation program induced by starvation of cells for nitrogen and carbon. Such environmental conditions activate coordinated, sequential changes in gene expression leading to production of haploid, stress-resistant spores. Sporulation comprises two rounds of meiosis coupled with spore morphogenesis and is tightly controlled to ensure viable progeny. This review concerns the regulation of differentiation process by nutritional and transcriptional signals.

18

Alpha-ketoglutarate dehydrogenase and lipoic acid synthase are important for the functioning of peroxisomes of Saccharomyces cerevisiae

51%

Smaczynska-de R. I. , Migdalski A. , Rytka J.

Cellular and Molecular Biology Letters

|

2004

|

tom 09

|

nr 2

EN

A method was devised to search for yeast mutants impaired in peroxisome functioning, indicating cross-talk between metabolic pathways. Two mutants were isolated; they are impaired in oleate utilisation and carry mutations in the KGD1 and LIP5 genes encoding the E1 component of the mitochondrial α-ketoglutarate dehydrogenase complex and lipoic acid synthase, respectively. The results presented indicate that the Kgd1 and Lip5 proteins are important for the expression of genes encoding peroxisomal matrix proteins, although they are not necessary for the biogenesis of this cellular compartment.

19

Functional and physical interactions of Krr1p, a Saccharomyces cerevisiae nucleolar protein

51%

Gromadka R. , Karkusiewicz I. , Rempola B. , Rytka J.

Acta Biochimica Polonica

|

2004

|

tom 51

|

nr 1

EN

The Krr1 protein of Saccharomyces cerevisiae is involved in processing of pre-rRNA and assembly of pre-ribosomal 40S subunits. To further investigate the function of Krr1p we constructed a conditional cold sensitive mutant krrl-21, and isolated seven genes from Schizosaccharomyces pombe whose products suppressed the cold sensitive phenotype of krrl-21 cells. Among the multicopy suppressors we found genes coding for translation elongation factor EF-1a, a putative ribose methyltransferase and five genes encoding ribosomal proteins. Using the tandem affinity purification (TAP) method we identified thirteen S. cerevisiae ribosomal proteins interacting with Krr1p. Taken together, these results indicate that Krr1p interacts functionally as well as physically with ribosomal proteins. Northern blot analysis revealed that changes in the level of krrl-21 mRNA were accompanied by similar changes in the level of mRNAs of genes encoding ribosomal proteins. Thus, Krr1p and the genes encoding ribosomal proteins it interacts with seem to be coordinately regulated at the level of transcription.

20

Sequencing and functional analysis of the yeast genome

51%

Zagulski M. , Herbert C. J. , Rytka J.

Acta Biochimica Polonica

|

1998

|

tom 45

|

nr 3

EN

The genome of the yeast Saccharomyces cerevisiae was sequenced by an international consortium of laboratories from Europe, Canada, the U.S.A. and Japan. This project is now finished and the complete sequence of the first eukaryotic genome was released to the public data bases in April 1996. An overview and preliminary analysis of the entire genome sequence was presented in a special issue of Nature in May 1997, entitled "The yeast genome directory". At its origin the Yeast Genome Sequencing Project provoked much debate and controversy; however, the final results obtained and the insights this has given us into the organisation and content of a eukaryotic genome have more than justified the expectations of the supporters of the project. The importance of genomic sequencing and analysis, especially of model organisms, is now widely accepted and this has resulted in the birth of the new science of genomics (Botstein & Cherry, Proc. Natl. Acad. Sci. U.S.A. 94, 5506, 1997). The information from gene and protein sequences ultimately lead to functional description of all genes. The main strategies describing possible ways to analyse the function of new genes that have been identified by systematic sequencing of Saccharomyces cerevisiae genome are described.