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EN
The study was carried out on 217 cows affected with acute or chronic udder inflammations. The subsequent procedures were followed: 1 - Nafpenzal MC (three times every 24 hours) - a control group consisting of 44 cows; 2 - Lydium-KLP: 0.02 mg/kg of body weight once and antibiotics 3 times intramuscular every 24 hours in 20 cows; 3-a single injection of Lydium KLP (0.01 mg/kg b.w. intravenously) and Mastisan PN intramammary (58 - cows); 4-a single intramammary administration of Mastisan PN after 4-7 days from unsuccessful Lydium treatment; 5 - Mastisan PN used in 67 control cows (94 quarters). The following percentage of recoveries was observed: group 1-78 per cent of quarters of 79.5 per cent of cows; group 2 - 87.9 per cent of the quarters in 90 per cent of the cows; group 3 - 92.8 per cent of the quarters in 94.8 per cent of the cows; 4 - 89.7 per cent of the quarters in 92.9 per cent of the cows; 5 - 84.4 per cent of the quarters in 83.6 per cent of the cows. At day 5 after the antibiotic administration, a lack of clinical signs in milk (34.0 per cent) and in 30.8 per cent of the quarters was observed. 59.3 per cent of recoveries were recorded at that time after the combined treatment. The studies indicated that Lydium KLP at a dose of 0.01 mg/kg increased the efficacy of intramammary antibiotic treatment in cows.
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tom 52
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nr 11
700-702
EN
The hygienic parameters of bulk tank milk were assessed in 10 farms (131 cows) before treatment with Mastisan PN, antibiotics and Lydium KLP - during the treatment and after completion of the treatment. Inflammation of the udders was found in 48 per cent of the cows; advanced forms of the disease were noticed in 10.3 per cent of the quarters and subclinical forms were found in 17.2 per cent of the quarters. All the farms had some problems with milk quality. The worst parameters of milk quality were observed before and during the treatment. The restoration to health, culling chronically infected cows, the control of milking hygiene and advisory service improved the milk quality. The average somatic cell count decreased to 81.8 per cent, the total count of bacteria was reduced to 71.0 per cent and total count of Staphylococci spp. to 52 per cent; the total count of coagulase positive strains of Staphylococcus spp. was diminished to 93 per cent, the amount of aesculin positive streptococci was lowered to 42.6 per cent and aesculin negative strains of Streptococcus spp. to 55.5 per cent. The presence of bacteria on milk for a long period after the treatment indicated a sloppy system of milk collection.
EN
Experiments were carried out on 137 cows. Before the drying period the udders were examined twice clinically, as well as their milk was tested bacteriologically and for its somatic cell level (CMT). Mastisan PN in the MC form (which is destined for mastitis treatment during lactation) was introduced into all quarters of the udders of 89 cows. Mastisan PN-DC containing a half dose of the Mastisan PN-MC was administered in 48 cows. Control examinations were performed twice, i.e. in the first and second week after calving. It was found that both drugs were highly effective (over 98 per cent). The prophylactic efficacy was 91 and 90.3 per cent respectively. Satisfactory therapeutic effects were observed in subclinical and clinical mastitis due to streptococci and staphylococci. The studies showed that Mastisan - a new drug elaborated at the National Veterinary Research Institute - was useful in the therapy of mastitis.
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