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EN
We evaluated the utility of Dukes' classification as a prognostic indicator in patients with squamous cell carcinoma of the thoracic esophagus treated with a combined-modality therapy (CMT). Experimental procedures: We analyzed a series of 71 patients, who underwent neoadjuvant chemotherapy (CDDP+5FU) — 50 patients or chemoradiotherapy (CDDP+5FU+radiation dose of 30Gy) — 21 patients, with esophagectomy and two-field extended lymph node dissection. The pathological staging was determined in all the patients according to the TNM and Dukes' classifications. Results: The differences in cumulative survival rates between particular TNM stages were statistically insignificant and in Dukes' classification the difference between pA and pB patients reached statistical significance (p=0.02) but between pB and pC patients it was statistically insignificant. Conclusions: 1. Pathological staging after neoadjuvant treatment in esophageal cancer patients is also a significant prognostic indicator. 2. Dukes' staging classification adopted for esophageal cancer could be more significant prognostic factor than the TNM classification.
EN
The aim of the present study was to assess the possible correlation of p53 with CEA and Ca 19-9 serum levels as well as with selected clinicopathological data. 46 patients, who were gastrectomized due to gastric cancer between 1998 and 2001, were analyzed. The concentration of CEA and Ca 19.9 was estimated in serum. Mean percentage of p53-positive cells in present group was 33,69 %. The comparison of mean percentage of p53-positive cells with IHC reaction intensity revealed statistically significant, directly proportional correlation, with p<0,001. Mean CEA and Ca 19-9 serum concentration were 1,75± 1,71 ng/ml, and 17,34±44,73 U/ml respectively. No significant correlation between p53-expression, CEA and Cal9-9 was noted respecting several clinicopathological data of tumors. However clear trend of higher CEA and Cal9-9 values in groups of potentially worse prognosis (T3-T4; Nl-2; III grade of disease) was observed.
EN
The aim of the study was to present the classification of anatomical variants of the operated stomach, based on radiological and historical data. Different anatomical variants of the operated organ were found in 431 out of 2034 patients examined in the years 2006–2010. Four main groups were established: abnormal position along longitudinal (I) and horizontal axis (II), as well as abnormal shape (III) and stomach connections (IV). An additional group (V) encloses mixed forms that combine features of two or more of the main groups. The first group contains the partial and total translocation of the stomach into the thoracic cavity after the partial or total oesophagectomy. Depending on the applied surgical techniques used during the total oesophagectomy, the stomach could be located anteriorly or posteriorly to the pericardial sac. An elongated and gastrectatic form often with signs of pylorostenosis is visible in patients treated by vagotomy. The consequences of fundoplication included: lack of or narrow cardiac angle, and often a mild form of stomach cascade. The most common abnormal shape of the stomach was secondary to gastrectomy and gastric bending. The final organ shape depends on the type of applied surgical procedure that maintains physiological connection with the duodenum or an un-anatomical one, mostly with the jejunal loop. In banding, the body of the stomach forms an hourglass at the level of the artificial adjustable band, typically applied in surgical treatment of obesity (slim surgery). (Folia Morphol 2012; 71, 3: 129–135)
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W artykule omówiono zastosowanie skanera dopplerowskiego w diagnostyce oparzeń skóry.
EN
In this paper the application of laser Doppler imager in the assessment of burns was described.
EN
Diverticula of the upper part of the alimentary tract, irrespective of their etiology, are frequently observed benign changes of the pharynx, oesophagus, stomach and duodenum. In the present work, patients of the II General Surgery Department of the Medical University of Lublin, with radiologically or endoscopically proved diverticula of the upper part of the alimentary tract, were examined. The presence of diverticula of such localisation was an indication for supplementary endoscopic or radiological examination. The localisation, size, diameter of the opening, mucosal relief of diverticula and its contiguity were checked and analysed. Our data suggest that both medical procedures are complementary to each other. All previously observed changes in diverticula of the thoracic part of the oesophagus and the infradiaphragm part of the alimentary tract were fully proved. The radiological examination gave a better view of Zenker’s diverticulum, especially in short and obese patients. Sampling and better visualisation of the diverticula opening testify to the unquestionable superiority of endoscopy. However, precise evaluation by radiological process fully completes the diagnostic protocol. Both diagnostic procedures are usually supplemented by manometric examination of the oesophagus and superior and inferior oesophageal sphincters. This enables the accurate diverticula etiology to be stated.
EN
Ectopic pancreas, a rare entity, is defined as pancreatic tissue lying outside its normal location without anatomical or vascular connections with the pancreas proper. Most occurrences of heterotopic pancreas are located in the stomach wall, duodenum, small intestine or anywhere in the gastrointestinal tract. The aim of this study was to describe the endoscopic, endosonographic (EUS) and radiological features of these lesions. Management of the ectopic pancreas remains controversial. The authors describe 12 patients and try to recommend different kind of treatment in the light of the symptoms, location and size of the lesions.
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