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Involvement of gonadotropins in induction of luteolysis in pigs

100%

Ziecik A. J. , Bodek G. , Ciereszko R. , Stepien A. , Kotwica G.

nr 2

Metody immortalizacji komorek i ich zastosowanie w badaniach nad rozrodem

100%

Bodek G. , Blitek A. , Kowalczyk A. E. , Kiewisz J. , Ziecik A. J.

nr 04B

537-540

After a few cell divisions primary cell cultures enter into a terminally nondividing state. Replicative senescence of cells involves a wide range of cellular events including changes in gene expression. Using immortalization methods it is possible to immortalize many of the primary cell cultures. The major advantage is that the immortalized cells represent the tissue of origin. It is possible to distinguish spontaneous and induced immortalization. The spontaneous immortalization of cultured cells is quite a rare event. Carcinogenic agents, radiation and viral oncogens can induce immortalization of cells. Transfection of cells with oncogens and telomerase activation generates an extended lifespan of cells. This review discusses various approaches to cell immortalization and the application of such cell lines for studies on animal reproduction.

The novel effect of hCG administration on luteal function maintenance during the estrous cycle/pregnancy and early embryo development in the pig

86%

Bołzan E. , Andronowska A. , Bodek G. , Morawska-Pucińska E. , Krawczyński K. , Dąbrowski A. , Zięcik A. J.

LH-hCG receptors in the porcine uterus - a new evidence of their presence in the cervix

86%

Stepien A. , Derecka K. , Gawronska B. , Bodek G. , Zwierzchowski L. , Shemesh M. , Ziecik A. J.

2000

tom 51

nr 4,2