Nowa wersja platformy, zawierająca wyłącznie zasoby pełnotekstowe, jest już dostępna.
Przejdź na https://bibliotekanauki.pl
Preferencje help
Widoczny [Schowaj] Abstrakt
Liczba wyników

Znaleziono wyników: 15

Liczba wyników na stronie
first rewind previous Strona / 1 next fast forward last
Wyniki wyszukiwania
help Sortuj według:

help Ogranicz wyniki do:
first rewind previous Strona / 1 next fast forward last
1
Content available remote Farthest points and bounded 2-functionals
100%
|
1999
|
tom Vol. 32, nr 3
531-538
EN
In this paper, we give some theorems on further characterizations and existences of E-farthest points in linear 2-normed spaces in terms of bounded linear functionals.
2
Content available remote Steady 3D incompressible flow analysis for the simplified train-tunnel interaction
63%
EN
This paper describes the phenomena that occur when a simplified model of train interacts with the tunnel at three locations - before, entering and leaving the tunnel. The Navier-Stokes equation is solved by introducing the artificial compressibility to change the governing equation type from the elliptic to hyperbolic. The Baldwin-Lomax turbulence modeling is employed to simulate the flow field with a Reynolds number of 10^6, and the computation domain is divided into three blocks considering the train and tunnel geometries. The grid is algebraically adapted determining the maximum solution change plane and solution weighting factors. The pressure in the adapted solution is not changed much, however, the skin friction is severely varied comparing with those of the non-adapted solutions. When the train enters into the tunnel, there are large increase in the surface pressure and skin friction distribution on the train surface.
4
Content available remote Some inequalities in 2-inner product spaces
51%
EN
In this paper we extend some results on the refinement of Cauchy-Buniakowski-Schwarz's inequality and Aćzel's inequality in inner product spaces to 2-inner product spaces.
EN
Mobile peer-to-peer (P2P) traffic is rapidly growing, but present P2P applications are not specifically designed to operate under mobile conditions. To assess the performance of the prevalent file sharing application BitTorrent in a mobile WiMAX network, we performed a measurement and analysis campaign. In this study, we use the obtained measurement traces to further investigate specific characteristics of this P2P network. In particular, we analyze the distribution of its peer population under mobile conditions and present a general classification scheme for peer populations in BitTorrent-like P2P networks. Further, we propose a simple heuristic to bound the outdegree of BitTorrent-like P2P systems when operating in mobile environments.
EN
Background: Previous studies indicated that cadmium (Cd) increases PI3-kinase/Akt phosphorylation, resulting in an alteration in GSK-3β activity. However, the mechanism of Cd-induced endoplasmic reticulum (ER) stress in neuronal cells has yet to be studied in needs further elucidation. We examined the role of GSK-3β in Cd-induced neuronal cell death and the related downstream signaling pathways. Methods: SH-SY5Y human neuroblastoma cells were treated with 10 or 20 μM BAPTA-AM and 1 μM wortmannin for 30 min and then incubated with 25 μM Cd for 12 h. Apoptotic cells were visualized via DAPI and PI staining. Data were evaluated with one-way analysis of variance (ANOVA) followed by Student’s t-test. Data are expressed as the means ± SD of experiments performed at least three times. Results: Treatment of human neuronal SH-SY5Y cells with Cd induced ER, stress as evidenced by the increased expression of GRP78, which is a marker of ER stress. Cd exposure significantly increased the phosphorylation of Akt at thr308 and ser473 and that of GSK-3β at ser9 in a time-dependent manner, while the total protein levels of GSK-3β and Akt did not change. Cd-induced apoptosis was higher in GSK-3β-knockdown cells than in normal cells. Conclusions: Our data suggest that Akt/GSK-3β signaling activated by Cd is involved in neuronal cell surviva
EN
An image processing technique was used to model the internal structure of aluminum foam in finite element analysis in order to predict the compressive behavior of the material. Finite element analysis and experimental tests were performed on aluminum foam with densities of 0.2, 0.25, and 0.3 g/cm3. It was found that although the compressive strength predicted from the finite element analysis was higher than that determined experimentally, the predicted compressive stress-strain curves exhibited a tendency similar to those determined from experiments for both densities. However, the behavior of the predicted compressive stress-strain curves was different from the experimental one as the applied strain increased. The difference between predicted and experimental stress-strain curves in a high strain range was due to contact between broken aluminum foam walls by the large deformation.
9
Content available remote Heron's formula in inner product spaces
51%
|
1998
|
tom Vol. 31, nr 1
97-102
EN
In this paper, we given Heron's formula in inner product spa
EN
Urban landscapes have a negative impact on bird species diversity, yet particular species thrive in urban communities. Like many other corvids, the Korean magpie is a successful colonizer of urban environments. On the semiurban campus of Seoul National University in Korea, we investigated whether magpies adjust territory size with building area and secondarily, whether they use vegetation and artificial components of their territory as indicators of prey density. We measured territorial areas and divided these into vegetation and artificial areas, distinguishing building area as a separate feature. We sampled prey density on each territory during the nestling stage. Territory size increased with the square root of building area (SRBA). As the length of building perimeter also increases with SRBA, we conclude that territory size was proportional to building perimeter. Prey density decreased with SRBA indicating that buildings had a negative impact on prey. Breeding success was also negatively related to SRBA. We suggest that magpies adjusted territory size according to the length of building perimeter due to a decline in prey density. As prey density declined, artificial pavement area was added to include open trash bins, which increase the availability of anthropogenic refuse such as discarded food. Vegetation area declined as prey density increased, but changes in vegetation area were minor and had little impact on prey availability measured at ground level. Structural cues were not used to adjust vegetation area, and artificial structural cues were not used to adjust territorial size over direct monitoring of prey density.
13
38%
EN
Over ninety percent of End Stage Renal Disease (ESRD) patients suffer from anemia due to insufficient endogenous production of human erythropoietin. Until the advent of Recombinant Human Erythropoietin (r-HuEPO) over 30 years ago, patients with ESRD were treated mainly with multiple blood transfusions. The high cost of r-HuEPO in addition to the narrow margin between an effective do-sage and toxicity in drug administration calls for optimal dosage strategy capable of minimizing cost and toxicity while at the same time achieving the desired do-sage outcome. It is well known from control theory that a controller can be de-signed for any plant provided there is readily available a valid model for such a plant. We present Robust Identification procedure, a dimensionality reduction technique capable of capturing the inherent dynamics of anemia patients; conse-quently producing individualized model suitable for robust control synthesis and any other controller design methodologies.
EN
The yeast Saccharomyces cerevisiae has a finite replicative life span. Yeasts pos­sess two prohibitins, Phb1p and Phb2p, in similarity to mammalian cells. These pro­teins are located in the inner mitochondrial membrane, where they are involved in the processing of newly-synthesized membrane proteins. We demonstrate that the elimination of one or both of the prohibitin genes in yeast markedly diminished the replicative life span of cells that lack fully-functional mitochondria, while having no effect on cells with functioning mitochondria. This deleterious effect was sup­pressed by the deletion of the RAS2 gene. The expression of PHB1 and PHB2 de­clined gradually up to 5-fold during the life span. Cells in which PHB1 was deleted in conjunction with the absence of a mitochondrial genome displayed remarkable changes in mitochondrial morphology, distribution, and inheritance. This loss of mi- tochondrial integrity was not seen in cells devoid of PHB1 but possessing an intact mitochondrial genome. In a subset of the cells, the changes in mitochondrial integ­rity were associated with increased production of reactive oxygen species, which co-localized with the altered mitochondria. The mitochondrial deficits described above were all suppressed by deletion of RAS2. Our data, together with published information, are interpreted to provide a unified view of the role of the prohibitins in yeast aging. This model posits that the key initiating event is a decline in mitochondrial function, which leads to progressive oxidative damage that is exacerbated in the absence of the prohibitins. This aggravation of the initial damage is ameliorated by the suppression of the production of mitochondrial proteins in the absence of Ras2p signaling of mitochondrial biogenesis.
first rewind previous Strona / 1 next fast forward last
JavaScript jest wyłączony w Twojej przeglądarce internetowej. Włącz go, a następnie odśwież stronę, aby móc w pełni z niej korzystać.