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2 Bulletin of the Veterinary Institute in Puławy

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Cardiopulmonary, biochemical, and haematological changes after detomidine-midazolam-ketamine anaesthesia in calves

100%

Kilic N.

2008

tom 52

nr 3

The aim of the study was to investigate the suitability of detomidine-midazolam-ketamine combination for umbilical surgery in calves. Fifteen calves subjected to umbilical surgery received detomidine (100 pg/kg b.w.), midazolam (0.5 mg/kg b.w.), and ketamine (10 mg/kg b.w.) intravenously (iv), as a mixture of the drugs. Rectal temperature, and heart, pulse, and respiratory rate were recorded before drug administration and at 5, 10, 15, 30, and 45 min after anaesthesia. Haematological and biochemical parameters were detected before drug administration, 15, 30, 45, and 60 min after drug injection and 24 h after anaesthesia. The combination of the compounds resulted in anaesthesia lasting about 45 min and a satisfactory immobilisation for umbilical surgery, although some hypoxaemia and respiratory acidosis occurred. The body temperature of the calves decreased significantly (P<0.05) during the anaesthesia from 38.5°C to 37.9°C. Haemoglobin, PCV, and RBC decreased significantly (P<0.05) for a short time. The values for plasma glucose, creatinine, and ALT increased significantly (P<0.05). However, they returned to the baseline at 24 h. Muscle relaxation was good and no complications were encountered.

Possible interaction between lameness, fertility, some minerals, and vitamin E in dairy cows

51%

Kilic N. , Ceylan A. , Serin I. , Gokbulut C.

tom 51

nr 3

Fifty-six cows that became lame within 60 d postpartum and 157 healthy cows (controls) were used in the study. The results from the following variables were analysed: calving to the first service interval, calving to conception interval, conception rate at the first service, and overall conception rate. Lameness was associated with a statistically significant 9 d increase in the interval from calving to the first service. In the lame cows, the interval from calving to conception was by 27 d longer (P<0.05) than those in the control cows. The conception rate at the first service was 41.4% (control - 54.6%). The serum vitamin E concentration was lower in the cows with lameness than that in the control cows: 2.31±0.24 µg/mL versus 2.44±0.12 µg/mL. However, the difference was not statistically significant. The serum P concentration in the lame cows (4.56±0.24 mg/dL) was significantly different from that in the controls (5.35±0.16 mg/dL). The mean Zn concentration was significantly lower one in the cows with lameness (57.81±3.8 µg/dL) compared with the control cows (85.51±6.01 µg/dL). These results suggest that there is a possible interaction between lameness, fertility, and serum P and Zn concentrations in dairy cows.