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EN
The outcome of surgical treatment of primary hyperparathyreoidism (PHP) is largely dependent on the radicality of the operation. This is sometimes difficult due to abnormal location of the glands. The use of intraoperative parathormone assay (IOPTH) and a handheld gamma-ray detector (HGRD) might influence the outcome of treatment.The aim of the study was to assess the feasibility of intraoperative parathormone assay and handheld gamma ray detector in surgical treatment of primary hyperparathyroidism.Material and methods. Prospective analysis of the treatment outcomes of patients with PHP undergoing surgery at the Dept. of General and Endocrine Surgery was accomplished. The patients were divided into two groups: G1 - patients in whom HGRD was used to intraoperatively locate the parathyroid glands; G2 - patients in whom both the HGRD and IOPTH were utilized. In all of the patients preoperative serum calcium and PTH measurements were taken. Thirty minutes before the scheduled start of the operation, patients from both groups received an 800 MBq dose of the Tc-MIBI radiomarker. Gamma radiation measurements were performed with the use of a Gamma Finder handheld device. In patients from the G2 group, serum PTH was assessed 10 minutes after the removal of the last gland. In the G1 group, bilateral neck exploration was performed. In the G2 group, the operation was brought to a close after the Miami criterion was met; in most cases, the surgery was limited to unilateral neck exploration.Results. Between 2007 and 2009 25 patients underwent surgery for PHP (group G1 - 12, group G2 - 13). There was one case of persistent hyperparathyroidism in group G1. All of the parathyroidectomies in group G2 were successful. No difference in the length of hospital stay were noted between the groups. The duration of surgery was longer in group G2.Conclusions. Surgical treatment of PHP with the combined use of a handheld gamma radiation detector and an intraoperative parathormone assay yields satisfactory results despite limited tissue preparation.
EN
Patients after spinal cord injury, severe brain trauma and cerebral stroke (ischemic or hemorrhagic) are often immobilized in bed or wheelchair for months or even years. One of the main risk factor for deep vein thrombosis is just prolonged immobilization.The aim of the study was to evaluate the frequency of symptomatic and asymptomatic thrombosis among immobilized patients because of severe brain damage and spinal cord injury.Material and methods. The study included 59 patients with tetra or paraparesis after severe brain damage or spinal cord injury, hospitalized in the University Hospital in Bydgoszcz in the Department of Rehabilitation over the period 2007-2008. All of them had lower extremities duplex-scan ultrasound as a screening examination and D-dimer testing.Results. Thrombosis was confirmed in nine patients (15% of all examined) and two patients (23%) in his group were of asymptomatic. 77% of diagnosed patients had only low extremities edema. Full symptomatic thrombosis with low extremities edema, increased warmness and redness were observed in 22% of patients.Conclusions. It is advisable to make periodical lower extremities venous system examination to exclude deep vein thrombosis. The risk of missed diagnosis in this group of patients is connected with increased percentage of embolism complications during the rehabilitation process. In patients after spinal cord injury, there are indications to examine the patients' venous system periodically.
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