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Oscylometria impulsowa w ocenie stanu drobnych dróg oddechowych

100%

Tomalak W. , Radliński J. , Czajkowska-Malinowska M.

2014

tom R. 90, nr 5

157--159

W pracy prezentowane są wyniki pomiarów własności układu oddechowego techniką oscylometrii impulsowej (IOS). Prezentujemy wyniki pomiarów uzyskanych u 555 osób dorosłych w wieku 45-96 lat (w tym 328 mężczyzn) oraz ich porównanie z klasycznie stosowanym badaniem spirometrycznym. Wyniki wskazują na wysoką korelację wskaźników spirometrycznych i oscylometrycznych, różnicowanie pomiędzy obturacją i jej brakiem oraz możliwość wykorzystania w ocenie stanu obwodowych dróg oddechowych.

The paper presents the results of assessing respiratory system properties using impulse oscillometry. We present the results obtained in 555 adults aged 45-96 years (328 men) and the comparison with classic spirometry. The results show high correlation between oscillometric and spirometric indices, differentiating among obstructed and non-obstructed patients and possibility to use in evaluating the state of small airways.

Verification of the new 'all ages' spirometric reference values for use in young Polish children of Caucasian origin

75%

Tomalak W. , Radliński J. , Bańka H. , Myszkal B. , Żarnowski K. , Doniec Z. , Fabry J.

tom Vol. 37, no. 1

167--171

Interpretation of the spirometric results in young children aged 3 years and onward was a difficult task, because existing reference values usually covered age range of 7–18 years. Recently two big studies concerning 'all ages' reference equations were published: the study of The Asthma UK Initiative (Stanojevic et al. AJRCCM 2009) and the so called GLI2012 values (Quanjer et al. ERJ 2012); both providing equations with LMS approach for spirometric reference values for age range of 3–95 years. The aim of the study was to test the applicability of the new sets of equations in a group of healthy Polish children of Caucasian descent. The analysis was performed on a data gathered from children admitted to outpatient department for diagnostic reasons. Children performed impulse oscillometry (IOS) measurements and spirometry. Elevated value of oscillometric resistance at 5 Hz (R5) eliminated children from analysis as well as forced expiratory time less than 1.5 s. Final analysis was performed on results obtained from 142 children aged 4–10 years. Z-scores and percent of predicted values were calculated for FEV1, FVC and FEV1/FVC using both sets; additionally z-score and percent predicted was also calculated for FEV0.75/ FVC using Stanojevic's equation. The distribution of all calculated z-scores was normal. For FEV1/FVC mean ± SD of z-score was 0.01 ± 0.80 using GLI2012 and -0.15 ± 0.79 using Stanojevic's set. Mean value of percent predicted values using GLI2012 was 100.2 ± 5.5% for FEV1/FVC, 107.4 ± 9.4% for FEV1 and 106.6 ± 10.1% for FVC. Our results confirm applica-bility of the new sets of reference values in young Caucasian children from Poland and point out the potential diagnostic value of FEV0.75/FVC.

Hand radiograms as an alternative for bone mass screening in cystic fibrosis

63%

Minarowska A. , Minarowski Ł., Ł , Tomalak W. , Zając J. , Pogorzelski A. , Radliński J. , Milewska, A.J , Kirpsza B. , Szajda, Sł. D , Chyczewska E.

nr 1

7-12

Purpose: Cystic fibrosis (CF) is a genetic, metabolic disease. Long-term therapy often leads to inappropriate calcification of bones. Dual X-ray absorptiometry (DXA) is considered a „gold-standard” for bone mineral density (BMD) assessment, but high usage costs can limit its availability. This paper compares two methods for BMD assessment in CF patients: hand radiograms method and densitometry using DXA method. Materials and methods: The study was performed in a group of 26 CF patients (10F, 16M), aged 7-30 years. In all cases, DXA measurements were performed, along with bone mass assessment using DENSY2004 system for digital assessment of hand radiograms. Stepwise binary logistic regression was used to examine the contribution of bone age, BMI, Cole's index and hand radiograms parameters to low BMD expressed as Z-score ≤-1SD. Results: Statistical analysis of the gathered data revealed that hand radiograms method allow for estimation of Z-score below -1SD with accuracy of 84.62% comparing to DXA. Sensitivity and specificity of this estimation in the studied group of CF patients was 86.67% and 81.82%. Conclusions: Hand radiograms method has good accuracy, sensitivity and specificity; therefore, it can be an alternative for DXA in BMD assessment. It can be implemented in chronic diseases affecting BMD like cystic fibrosis.