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Content available remote On a pair of geometric parameters of Orlicz norm
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tom [Z] 41
257-263
EN
Background: Our previous study showed that during in vitro experiments changes in calcium concentration were associated with apoptosis. We presumed that the calcium ion might play a role as intermediate messenger for apoptosis-related genes. No such evidence has been reported in the literature. Here, we investigate the effect of calcium ionophore A23187 on the apoptosis of rat hepatic stellate cells (HSCs) stimulated by transforming growth factor-β1 (TGF-β1) to explore the mechanism of apoptosis through the endoplasmic reticulum stress pathway. Methods: The apoptotic rate was determined using flow cytometry. The changes in Ca2+ level in HSCs were examined with laser confocal microscopy. The expressions of caspase-12 GRP78 and caspase-9 were assayed via western blot. Results: The respective apoptosis rates for the blank group, the TGF-β1 group and the TGF-β1 + low, medium and high dose calcium ionophore A23187 groups were 3. 40 ± 0.10%, 1.76 ± 0.12%, 5.86 ± 0.31%, 11.20 ± 0.48% and 15.08 ± 0.75%, with significant differences between the groups (p < 0.05). The concentration of Ca2+ and the expression of the GRP78, caspase-9 and caspase-12 proteins significantly increased with increasing calcium ionophore A23187 doses (p < 0.05). Conclusion: Calcium ionophore A23187 increased intracellular Ca2+ and activated endoplasmic reticulum stress, which promoted HSC apoptosis.
EN
Antioxidant enzymes in chloroplasts and chlorophyll fluorescence parameters of leaves of Puccinellia tenuiflora (Turcz.) scribn.et Merr. under isotonic Na2CO3 and NaCl stresses were studied. Ascorbate peroxidase (APX) and superoxide dismutase (SOD) activities showed a similar increasing trend and then decreased with the decreasing osmotic potential of culture solution, peaking at –4.74 x 10⁵ Pa under NaCl stress and at –3.40 x 10⁵ Pa under Na2CO3 stress. APX, glutathione transferase and SOD activities were higher under NaCl stress than those under Na2CO3 stress, and higher activities of antioxidant enzymes in chloroplasts were accompanied by lower MDA content under NaCl stress. Fv/Fm, Fv/Fo and Fv'/Fm' all initially increased and then decreased with the decreasing osmotic potential of culture solution, while ΦPSII, qNP and HDR showed a constant increase. Fv/Fm, Fv/Fo, ΦPSII and qNP under NaCl stress were also shown to be higher than those under Na2CO3 stress. The present study suggested that acidity played an important role in the hurt to Puccinellia tenuiflora seedlings, which was due to higher activities of antioxidant enzymes, qNP and ΦPSII, and the Na2CO3 resistance to Puccinellia tenuiflora was also supposed to be less than NaCl resistance in present work.
EN
We have successfully designed and demonstrated a co-planar waveguide (CPW) Mach-Zehnder (MZ) electro-optic (EO) modulator using a strip-loaded waveguide structure. The hybrid material, easily synthesized by sol-gel process, with a large EO coefficient of r33 = 50 pm/V and a long- -term stability at 80 °C for 200 hours is selected as the active layer. A simple and easily fabricated strip-loaded waveguide structure is designed for utilizing the EO material and reducing the coupling loss with optical fiber. The optimized design principles of the efficient transmission for such a modulator are discussed. The measured half-wave voltage V? of 8.5 V for the MZ modulator is gained at 1550 nm and shows a good agreement with the simulating result.
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tom S 2
188--194
EN
Intense marine reclamation activities bring obvious benefits, meanwhile, these activities also influence the coastal natural formation, hydrodynamic processes and water environment etc. In order to investigate the exact influence in the Qinzhou Bay brought by marine reclamation behaviors in recent years, based on the remote sensing image data in the Qinzhou Bay in 2006, 2008, 2009, 2012 and 2014, with the help of GIS and RS software, the thesis interprets Qinzhou Bay coastline and artificial reclamation by man-machine interaction and makes quantitative analysis in the Qinzhou Bay coast evolution recently. The results show: (1) Qinzhou Bay coastal morphology change degree was strong in 2006 - 2012 and the coastline changed greatly. Originally part of the natural shore segments which had twists and turns were gradually filled into artificial coast, the coast constantly advanced to the sea, coastline became regular and straight; (2) The change degree of coastline was relatively small in 2006-2008, the average artificial coastline increased 8.86 km/a, the average artificial reclamation area was 20.79 km2 /a; in 2008-2012, the change range of coastline was the greatest, coastline changed most severely, the average artificial coastline increased 16.07 km/a, the average artificial reclamation area was 58.52 km2 /a; however, in 2012-2014, coastline change degree relatively slowed, the average artificial coastline increased 4.04 km per year, the average artificial reclamation area was 3.464 km2 /a. (3) Compared to the studies of predecessors, the innovation of this paper is that it is the first to carry out the detailed research on coastline evolution caused by reclamation engineerings of the Qinzhou Bay, then formed the change results on coastline that caused by intense human activities in the Qinzhou Bay, provided the area of the marine environment protection with full and accurate data.
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