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Content available Sclareol and cancer prevention: a mini-review
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Sclareol is a labdane-type phytochemical compound that, due to its pharmacological attributes and historical use in herbal medicine, has attracted noteworthy attention. Numbers of research, mainly through testing on human and animal models, have demonstrated a wide range of effects, by which using sclareol may be considered as an important method in cancer prevention. By using the key words sclareol, cancer, neoplasia, we extracted the articles published up to September 2020 through search in PubMed, SID, ISI Web of Science, Scholar, and Scopus. This study aimed to summarize the research and studies on sclareol and its effects on cancer prevention and treatment.
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Cancer is responsible for the death of millions of people all around the world. Among the large group of cancers, the prevalence of breast cancer is highest in women. Therapeutic interventions, including removal surgery, radiation therapy, hormone therapy, and chemotherapy which is largely used, may cause adverse effects on the quality of patients’ life. This fact has encouraged researchers to find natural substances such as honey to overcome harmful effects. Nowadays, honey is recommended for plenty of abnormalities because of its antioxidant, anti-inflammatory, and antimicrobial properties. Various studies have been conducted to explore the anticancer benefits of different types of honey from different origins. In this review, we are going to summarize in-vitro, animal, and human studies on the anti-breast cancer potential of honey.
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