Wyniki wyszukiwania - Biblioteka Nauki

1

Półmostkowy tyrystorowy regulator napięcia

100%

Rylski A. , Wojturski J. , Nizioł M. , Post P.

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tom R. 91, nr 10

176-178

PL

W artykule przedstawiono układ półmostkowego regulatora napięcia dla kąta zapłonu tyrystora z przedziału 110-150°. Przesunięcie zapłonu tyrystora do kąta o wartości około 110° zrealizowano na transformatorze małej mocy – przesuwającym kąt o 180° oraz obniżającym napięcie sieciowe i przesuwniku fazy RC w układzie różniczkującym – przesuwającym napięcie o kąt -70°. Regulację kąta zapłonu w zakresie 110- 150° zrealizowano poprzez zmianę amplitudy napięcia sterującego, której wartość określa moment zapłonu tyrystora.

EN

A circuit with semi-bridge thyristor voltage regulator for thyristor ignition angle in the range 110-150 degrees is presented. A shift of the ignition angle equals about 110 degrees was realized on the low power transformer (which shifts ignition angle of 180 degrees and reduces line voltage) and RC phase shifter in a differentiation circuit, shifting voltage by an angle of -70 degrees. Regulation of ignition angle in the range between 110-150 degrees was accomplished by changing an amplitude of a control voltage, which specifies moment of thyristor’s ignition.

2

Immunohistochemical Fascin-1 expression correlate with lymph node and distant metastases in pancreatic ductal adenocarcinoma

63%

Pryczynicz A. , Nizioł M. , Miniewska K. , Kamińska D. , Kuczyńska P. , Zińczuk J. , Zaręba K. , Guzińska-Ustymowicz K.

Progress in Health Sciences

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2018

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tom 8(2)

124-130

EN

Introduction: Pancreatic cancer is characterized by its aggressiveness and poor prognosis. Furthermore, mortality is one of the highest among all types of cancers. It has been observed that the expression of Fascin-1 (the actin-bundling protein which enables the motility of cells) is higher in cancer cells and is correlated with invasiveness and metastasis. Purpose: To investigate the expression of Fascin-1 in histopathological specimens from patients treated for pancreatic cancer and its relationship with histopathological parameters. Materials and methods: The study was performed on a group of 52 patients diagnosed with pancreatic cancer in the Medical University of Bialystok Clinical Hospital. The expression of Fascin-1 was evaluated in tissue samples using the immunohistochemical method and was rated as “present” or “absent”. The analysis of histopathological parameters was performed in correlation with Fascin-1 expression. Results: Fascin-1 expression was observed in the cytoplasm of cancer cells in 42/52 cases (80.8%). Fascin-1 expression occurred more frequently among patients with lymph node metastases (92.6%) than without this type of metastases (68%) (p=0.024). Likewise, the expression of the investigated protein was observed more often with the presence of distant metastases (100%) than without those metastases (74.4%) (p=0.043). There were no statistically significant differences about age, sex, histological type of cancer, grade of histological differentiation, desmoplasia, inflammatory infiltration, foci of hemorrhage, necrosis, and MVD. Conclusion: The expression of Fasicn-1 is correlated with the presence of metastases and can be a useful marker of pancreatic cancer involvement.

3

Symptoms of colorectal cancer contributes to its localization and advancement

63%

Nizioł M. , Kostrzewska B. , Kamińska D. , Domurat M. , Zińczuk J. , Misiura M. , Guzińska-Ustymowicz K. , Pryczynicz A.

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tom 1

76-82

EN

Introduction: Colorectal cancer is one of the most common cancers occurring in Poland. Unfortunately, this cancer is most often diagnosed at the time of great advancement. This is caused by the appearance of specific symptoms only in the late stages of cancer. Also, such low detection of early stages of adenocarcinoma may be caused by disregarding of slight symptoms. Purpose: To analyse symptoms in patients with colorectal cancer and correlate with chosen clinical-pathological parameters. Materials and methods: The study group consisted of 46 patients diagnosed with colorectal cancer. Information on symptoms associated with cancer (subjective and objective) have been selected from patients' medical history. The presence of these symptoms was correlated with the age and sex of patients, tumor location, histological type of cancer, grade of histological malignancy (G), stage of tumor (T stage), presence of lymph node metastases and distant metastases. Results: It has been shown that the presence of pain complaints described by the patient are associated with the occurrence of cancer in the colon. The painfulness and pathological resistance diagnosed by the physician are more often associated with cancer located in the colon. In the case of tumors located in the rectum, faecal admixtures appear more frequently. It has also been shown that the presence of admixtures of blood and mucus in the stool is associated with more advanced local tumors, infiltrating pericolorectal tissues (T3 + T4). Conclusions: Familiarity with clinical symptoms of colorectal cancer could make patients more sensitive to more often screening for cancer. Analysis of these symptoms could indicate to the physician the location or stage of the cancer.