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tom nr 7
514-518
PL
Dynamiczny rozwój sieci Internet powoduje przeciążenie publicznych sieci telekomunikacyjnych. W firmie Alcatel opracowano 3-fazową strategię modernizacji i przebudowy central telefonicznych Alcatel 1000 S12 w uniwersalne systemy komunikacyjne odpowiednie do budowy wąsko- i szerokopasmowych sieci dostępowych o dużej pojemności. Do sieci dostępowej mają być masowo wprowadzone techniki ISDN i ADSL.
EN
Rapid development of Internet results in overload of existing publictelephone networks. Alcatel has developed a 3-phase strategy for update and extension of Alcatel 1000 switching system into an versatile system suitable for implementation of both narrowband and broadband high performance access networks. Access networks will be based on massive deploymant of ISDN i ADSL technologies.
EN
Taking advantage of recent developments in molecular biology and imaging, we have developed a system for monitoring status of transplanted cells non-invasively. We use high-resolution MRI to acquire information about the position of grafted cells and reporter gene-based bioluminescent imaging (BLI) to monitor their survival and differentiation. Here, we report on two different approaches for the in vivo imaging of glial precursors cells (GRPs). Approach I: Monitoring of the targeted, intravascular cerebral delivery of GRPs. Cells were engineered to express VLA-4 integrin (to enhance vascular adhesion) and were labeled with the MR contrast agent Feridex. Recipient rats were injected i.p. with lipopolysaccharide, a known inducer of endothelial VCAM-1 expression, and the cells were infused into the carotid artery. MRI demonstrated extensive hypointense regions, indicating successful targeting. Approach II: Monitoring of the survival and differentiation of intracerebrally injected GRPs. Cells were engineered to express luciferase under the control of a constitutive or the cell-type-specifi c promoters and were injected into the brain of immunodefi cient or immunocompetent mice. BLI demonstrated that transplanted GRPs survived for extended periods of time in immunodefi cient animals, while, in immunocompetent animals, rejection was initiated two weeks after grafting. With cell type-specifi c promoters, we were able to visualize the process of glial differentiation in vivo.
EN
One of the simplest device realisations of the calssic particle-in-the-box problem of basic quantum mechanics is the quantum well infrared photodetector (QWIP). In this paper we discuss the effect of focal plane array non-uniformity on the performance, optimisation of the detector design, material growth and processing that has culminated in realisation of large format long-wavelength QWIP cameras, holding forth great promise for many applications in 6-18 micron wavelength range in science, medicine, defence and industry. In addition, we present the recent developments in long-wavelength/very long-wavelength dualband QWIP imaging camera for various applications.
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