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EN
A nine year-old intact tomcat was admitted into the Clinic for Small Animals because of adipsia and oliguria, which had been persisting for several weeks. A few weeks earlier the cat was treated for a complicated skin wound. Nothing but moderate dehydratation was discovered in clinical examination. For a more detailed examination of the animal’s status, blood and urine were collected for a basic check-up. All parameters were within reference values apart from mild hyponatremia. A non-specific course of the disease and blood check results aroused suspicion of feline hypoadrenocorticism (Addison’s disease). ACTH stimulation test was conducted. It revealed a failure to respond to exogenous ACTH administration, thus confirminh the initial diagnosis. An X-ray of the thorax and ultrasonography of the abdomen displayed no pathological alterations. Antibiotics and a temporary subcutaneous fluid therapy with 0.9% saline were implemented so as to restore proper hydration and electrolyte balance. Then a chronic therapy with prednisone (Encorton 5 mg) at a dose of 0.5 mg/kg body weight and fludrocortisone (Cortineff 0.1 mg) 0.05 mg/animal was applied. Over 16 months have passed since the primary diagnosis was made. During that time the health status of the cat has remained satisfactory apart from a temporary deterioration due to the appearance of a strong stressing agent, which necessitated the application of a short course of fluid therapy, doubling of prednisone doses and supplementation of phosphor. Rapid response to the modified therapy has confirmed the accuracy of the initial diagnosis. Moreover, a typical course of feline hypoadrenocorticism, available diagnostic methods as well as factors affecting prognosis were discussed.
EN
The toxin used was a sterile crude extract of a sonicated strain A11/2a of Pasteurella mutocida (P.m.) type D, isolated from a pig with atrophic rhinitis. Fifteen rabbits aged 8—12 days were being given 8 or 12 doses of the toxin every 3—4 days intramuscularly or subcutaneously. According to the same schedule 9 control litter-mates were being given an extract from the nontoxigenic strain 01d9 of P.m., type D. All the rabbits were then sacrificed, necropsied and the specimens were taken for histopathological evaluation and the nasal swabs for bacteriological examination. No toxigenic P.m. or Bordetella bronchiseptica were isolated from those animals as tested by the guinea pig skin test. All the rabbits which had received the toxin showed from mild to severe atrophy of the nasal turbinates. Microscopic lesions included degeneration of their osseous core, necrotic changes of the osteocytcs and an increased number of osteoblasts and osteoclasts. Hyperaemia of the nasal mucosa was also seen and in a few cases bionecrosis was found in the osteoblasts. Degeneration was found in the liver and myocardium. In the lymphatic tissue hypertrophy of the follicles was observed. Control rabbits showed no changes with the exception of one animal with mild turbinate atrophy. It is concluded that in natural atrophic rhinitis in rabbits the dermonecrotic toxin of P.m. plays a similar role as in this kind of disease in pigs.
EN
Q fever is a worldwide zoonosis that is manifested as a reproductive failure in animals and by polymorphic, nonspecific symptoms in humans. The infection may be acquired through the respiratory or alimentary route or an arthropod bite. The diagnosis of Q fever relies mainly upon serology: indirect immunofluorescence assays (IFA), complement fixation (CF) tests or enzyme-linked immunosorbent assays (ELISA) are used to detect antibodies against Coxiella burnetii in sera of infected animals. The aim of our study was to evaluate the agreement of the commercially available ELISA kit and CF test using statistical methods (Kappa value). We used serum samples that were collected from 122 dairy cows from one herd in central Poland. The general health status of the herd was good, and the animals were clinically normal. Our results showed a low agreement (Kappa value = 0.376) between the commercially available ELISA and CF test.
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