Wyniki wyszukiwania - Biblioteka Nauki

1

Skutki zdrowotne zatrucia srodowiska metalami ciezkimi. II. Miedz

100%

Baranowska-Bosiacka I.

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tom 97

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nr 06

148-149

2

Skutki zdrowotne zanieczyszenia srodowiska metalami ciezkimi. Olow.

100%

Baranowska-Bosiacka I.

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nr 07-08

176-178

3

Zawartość niektórych metali ciężkich w mięśniach i wątrobach leszczy (Abramis brama l.) odławianych w estuarium Odry

67%

Hłyńczak A. J. , Baranowska-Bosiacka I. , Fokt M.

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tom Vol. 24, no. 1

69-78

PL

Wody Zalewu Szczecińskiego i Zatoki Pomorskiej ulegają postępującemu antropogenicznemu zanieczyszczeniu metalami ciężkimi. Wraz ze wzrostem skażenia wód maleje szansa na zdolności ich samooczyszczania, ponieważ wprowadzone w nadmiarze do ekosystemu metale nie ulegają biodegradacji i krążą w łańcuchach troficznych. Celem monitoringowych badań prowadzonych systematycznie od roku 1992 jest analiza zawartości Zn, Pb, Cd, Cu w mięśniach i wątrobie leszczy (Abramis brama|) , odławianych w wodach Zalewu Szczecińskiego. Stwierdzone poziomy metali ciężkich w mięśniach i wątrobach są wysokie: Zn - 3,7681 - 7,3300mg/g (mięśnie) i 4,8510 - 26,85mg/g (wątroba); Pb - 0,17900 - 1,7900mg/g (mięśnie) i 2,7298 - 6,32mg/g (wątroba); Cd - 0,0032 - 0,17mg/g (mięśnie) i 0,051 - 0,4mg/g (wątroba); Cu - 0,26 - 0,56mg/g (mięśnie) i 5,88 - 14,9mg/g (wątroba).

EN

Waters of Szczecin lagoon and Pomeranion Bay undergous to progressive anthropogenic contamination with heavy metals. Together with contamination of water change of self-purification diminishes, because exces of introduced metals not degradates in trophic chain. Since 1992y. Monitoring of contents of Zn, Pb, Cd, Cu in muscles and livers of breams catched in Szczecin lagoon waters was undertaken. Ascertained levels of heavy metals in muscles and livers are relatively high: Zn - 3,7681 - 7,3300mg/g (muscles) i 4,8510 - 26,85mg/g (livers); Pb - 0,17900 - 1,7900mg/g (muscles) i 2,7298 - 6,32mg/g (livers); Cd - 0,0032 - 0,17mg/g (muscles) i 0,051 - 0,4mg/g (livers); Cu - 0,26 - 0,56mg/g (muscles) i 5,88 - 14,9mg/g (livers).

4

Wystepowanie niektórych metali ciężkich w wybranych zbiornkach wodnych Szczecina

67%

Hłyńczak A. J. , Baranowska-Bosiacka I. , Janeczko A.

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tom Vol. 24, no. 1

57-67

PL

Akweny zlokalizowane w aglomeracjach miejskich są często wykorzystywane jako zbiorniki retencyjne wód opadowych spływających z miejskiej kanalizacji deszczowej. Działanie czynników antropogenicznych (ścieki komunalne, rolnicze [ogrodowe], przemysłowe) prowadzi do silnego zanieczyszczenia, a często do degradacji tych zbiorników. Obok innych zanieczyszczeń, zawiesiny spływające do wód powierzchniowych niosą zwykle znaczne ilości metali ciężkich. Stężenie tych metali w toni wodnej zależy od wielkości ich zrzutu oraz bardzo wielu różnych czynników: cech morfometrycznych zbiornika, chemizmu wody, stanu redoks osadów itp. Celem badań było określenie stopnia zanieczyszczenia metalami ciężkimi toni wodnej zbiorników: Rusałka, Słoneczne, Głębokie i Syrenie Stawy. Próby wody pobierano wzdłuż spływu w zbiorniku. Oznaczono stężenia Zn, Pb, Cd i Cu. Stwierdzono, że wszystkie badane wody zawierały podobne, stosunkowo znaczne stężenie oznaczonych metali oraz zaobserwowano sezonowość koncentracji metali związaną z intensywnością występowania opadów atmosferycznych.

EN

Aquens localised in urban areas are often used as retention reservoirs of rainfalls that go thrugh sewage system. Anthropogenic impact (municipal, agricultural and industrial sewages) leads to strong contamination and often to degradation of such reservoirs. Besides other pollution, suspenssion usuelly carries great amonnts of heavy metals. Concentration of the metals in water depends on many factors: morphometric features of reservoir, chemism of water, red-ox status of sediments and so on. Investigations were aimed at determining the concentration of heavy metals in lake: Rusałka, Słoneczne, Głębokie and Syrenie Stawy ponds. Samples were taken alongside of reservoirs Zn, Pb, Cd, Cu and were determinized. Waters of the reservoirs contein relativeli similar concentration of the metals, and seasonic atmospheric falls

5

Biochemical and medical importance of vanadium compounds

67%

Korbecki J. , Baranowska-Bosiacka I. , Gutowska I. , Chlubek D.

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nr 2

EN

Vanadium belongs to the group of transition metals and is present in the air and soil contaminants in large urban agglomerations due to combustion of fossil fuels. It forms numerous inorganic compounds (vanadyl sulfate, sodium metavanadate, sodium orthovanadate, vanadium pentoxide) as well as complexes with organic compounds (BMOV, BEOV, METVAN). Depending on the research model, vanadium compounds exhibit antitumor or carcinogenic properties. Vanadium compounds generate ROS as a result of Fenton's reaction or of the reaction with atmospheric oxygen. They inactivate the Cdc25B2 phosphatase and lead to degradation of Cdc25C, which induces G2/M phase arrest. In cells, vanadium compounds activate numerous signaling pathways and transcription factors, including PI3K-PKB/Akt-mTOR, NF-κB, MEK1/2-ERK, that cause cell survival or increased expression and release of VEGF. Vanadium compounds inhibit p53-dependent apoptosis and promote entry into the S phase of cells containing functional p53 protein. In addition, vanadium compounds, in particular organic derivatives, have insulin-mimetic and antidiabetic properties. Vanadium compounds lower blood glucose levels in animals and in clinical trials. They also inhibit the activity of protein tyrosine phosphatase 1B. By activating the PI3K-PKB/Akt pathway, vanadium compaunds increase the cellular uptake of glucose by the GLUT4 transporter. The PKB/Akt pathway is also used to inactivate glycogen synthase kinase-3. The impact of vanadium compounds on inflammatory reactions has not been fully studied. Vanadium pentoxide causes expression of COX-2 and the release of proinflammatory cytokines in a human lung fibroblast model. Other vanadium compounds activate NF-κB in macrophages by activating IKKβ.

6

The effect of reactive oxygen species on the synthesis of prostanoids from arachidonic acid

67%

Korbecki J. , Baranowska-Bosiacka I. , Gutowska I. , Chlubek D.

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tom 64

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nr 4

7

Cyclooxygenase pathways

67%

Korbecki J. , Baranowska-Bosiacka I. , Gutowska I. , Chlubek D.

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nr 4

8

Niektore metale ciezkie w wybranych tkankach jazgarza [Gymnocephalus cernuus L.]

67%

Hlynczak A. J. , Baranowska-Bosiacka I. , Domagala J. , Rutkowska M.

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1996

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tom 20

25

9

Contents of some heavy metals in chosen tissues of Gymnocephalus cernuus L.

67%

Hlynczak A. J. , Domagala J. , Baranowska-Bosiacka I. , Rutkowska M.

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1996

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tom 33

10

The purine nucleotide content in human leukemia cell lines

67%

Baranowska-Bosiacka I. , Machalinski B. , Tarasiuk J.

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nr 2

11

Content and localisation of heavy metals in thalli of hemerophilous lichens

67%

Baranowska-Bosiacka I. , Pienkowski P. , Bosiacka B.

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tom 10

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nr 4

EN

For the purpose of this work an epiphytic lichen species, Hypogymnia physodes (L.)Nyl., was used. Thalli of the lichen were treated with solutions of nitrate salts of heavy metals, including Zn(NO3)(2), Cu(NO3)(2), Pb(NO3)(2), and Cd(NO3)(2). To simulate the acid rain impact, pH of the metal mixture was lowered to pH 4, using Na2S2O5. Content of heavy metals was determined after a standard UV mineralization method (water solution) and burning method (in temperature 450 degreesC- thalli), using a Microcomputer Voltage-ammeter Analyser (MAW). After two months exposure of the lichen to the mixture of heavy metal nitrates it was ascertained that there was an increase of accumulation of Zn, Pb, Cu, and Cd in the thalli; a decrease of thalli pH caused increased uptake of toxic elements by the lichen; Pb and Cd remained mainly on the surface of the thalli and in the cell walls, whilst Zn and Cu penetrated to the protoplast.

12

Disorders of purine metabolism in human erythrocytes in the state of lead contamination

67%

Baranowska-Bosiacka I. , Hlynczak A. J. , Wiszniewska B. , Marchlewicz M.

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nr 5

EN

Although many countries now have programs to lower the levels of lead in the environment, human exposure to Pb remains of concern to public health officials worldwide. The mechanisms of lead toxicity are still not fully understood, but recent findings have recognized the significance of the lead-induced impairment of the cell energy metabolism. This review outlines recent hypotheses and evidence on the role of nucleotide purines in erythrocyte metabolism regulation. It also describes the resynthesis and decomposition of purine nucleotides in erythrocytes, lead distribution in blood and its influence on purine conversion pathways and both glycolytic and pentosophosphate pathway enzymes in erythrocytes.

13

Morphine dependence in rats: effect of low-level lead exposure during perinatal period

59%

Listos J. , Listos P. , Baranowska-Bosiacka I. , Chlubek D. , Fidecka S.

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nr S

EN

In the present experiments the effect of perinatal lead exposure on development of morphine dependence in rats was examined. Female rats were gavaged daily with 0.1 % lead acetate solution. Lead ions were administered through pregnancy and two months through lactation. In the same time control animals received water. The development of morphine dependence was obtained by administration of increasing doses (10, 20, 30, 40, 50, 50 mg/kg, ip) of morphine for six consecutive days in lead intoxicated rats and in control animals. 20 min after the last injection of morphine the withdrawal signs were induced by application of naloxon at dose of 2 mg/kg, ip. Secondly, the development of morphine tolerance to antinociception activity was studied in the tail-flick test in lead intoxicated rats. Then rats received morphine (10 mg/kg, ip) for seven consecutive days and test was performed on 1st and 7th day of the experiment. The experiments have shown that in lead intoxicated rats morphine withdrawal signs (jumping, wet dog shakes) were significantly potentiated than in control animals. The morphine tolerance was also more expressed in lead intoxicate rats. The obtained results have shown that prenatal lead exposure intensify the effects of chronic treatment with morphine in rats.

14

Expression of metalloproteinase 2 (MMP-2) and metalloproteinase 9 (MMP-9) in THP-1 macrophages cultured with three-dimensional titanium mini-plate systems used for surgical treatment of condylar fractures

59%

Sikora M. , Baranowska-Bosiacka I. , Lukomska A. , Goschorska M. , Chlubek D.

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nr 3

15

The glutathione antioxidant system in goat kids erythrocytes in the first week of life

59%

Skotnicka E. , Muszczynski Z. , Dudzinska W. , Baranowska-Bosiacka I. , Janus K.

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nr Supplement 4

16

Androgen levels and apoptosis in the testis during postnatal development of finasteride-treated male rat offspring

59%

Kolasa-Wolosiuk A. , Misiakiewicz-Has K. , Baranowska-Bosiacka I. , Gutowska I. , Wiszniewska B.

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2015

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tom 53

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nr 3

17

Effect of zinc supplementation on the distribution of lead in tissues of rats intoxicated by lead compounds

51%

Baranowska-Bosiacka I. , Gutowska I. , Skibicka E. , Sobieniecki A. , Stanczyk-Dunaj M. , Skotnicka E. , Chlubek D.

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tom 20

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nr 1

EN

The permissible threshold level of lead in blood (Pb-B) is currently established at 5 mg dL-1, but evidence suggests that it is impossible to determine the safety threshold for lead (Pb) and any exposure, especially in children, must be considered as potentially harmful. Methods used to reduce the concentration of Pb in blood (e.g. EDTA, penicillamine) are not always effective and are associated with serious side effects. One of the proposed dietary supplements in the case of exposure to Pb and low blood Pb concentrations is zinc (Zn), but the published literature on its effectiveness is limited. Therefore, the aim of this study was to clarify whether Zn supplementation may help reduce the concentration of Pb in the blood and tissues of rats, at the Pb-B level previously recognized as safe. Tests were performed on 6-8 week old male Wistar rats. Rats were divided into control and experimental groups: Group C – rats receiving drinking water ad libitum for 4 weeks; Group Pb – rats receiving Pb acetate 0.1% (PbAc) in drinking water ad libitum for 4 weeks; Group Zn – rats receiving ZnCO3 300 mg kg-1 diet for 4 weeks; Group Pb+Zn – rats receiving PbAc in drinking water ad libitum plus 300 mg ZnCO3 kg-1 diet for 4 weeks. The applied dose of 300 mg of ZnCO3 kg-1 diet results in a high but non-toxic Zn level. The concentrations of Pb and Zn in blood, plasma, liver and bone were determined by emission spectrometry in inductively coupled argon plasma (ICP OES). Incidental exposure of adult rats to Pb at doses resulting in the level of Pb in blood below the previously recognized as safe one caused: (i) increased Pb concentration in the bones and plasma and its reduction in the whole blood and liver (ii) simultaneous supplementation of rats exposed to Pb with a high but non-toxic dose of zinc did not result in the reduction of the Pb concentration in the blood and tissues of rats, nor did it induce any changes in the distribution of Pb in the examined tissues (iii) supplementation of diets with a high but non-toxic dose of Zn is not an effective method of reducing the concentration of Pb in blood at Pb-B previously recognized as safe. However, the therapy consisting of zinc supplementation to support the action of chelators could be crucial for the elimination of Pb from the body.

18

Biomonitoring of lead and fluoride contamination in forests using chemical analysis of hard tissues of roe deer (Capreolus capreolus L.)

51%

Sobota S. , Baranowska-Bosiacka I. , Gutowska I. , Kupiec M. , Dusza E. , Machoy Z. , Chlubek D.

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nr 2

EN

Our study assesses environmental lead and fluoride pollution in West Pomeranian forests in Poland, on the basis of chemical analysis of antlers and skull bones of roe deer (Capreolus capreolus L.) from the surroundings of Szczecin and Drawsko Pomorskie, Poland. Lead was measured by atomic absorption spectrometry, and fluorides by using an ion-selective electrode. Our study indicates greater lead contamination in the forests near Drawsko Pomorskie than in the forests near Szczecin. The cause may be their long-term exploitation as a military area. The roe deer population near Szczecin is exposed to increased fluoride pollution, but the concentration of fluoride in hard tissues of roe deer has diminished considerably in comparison with data acollected 10 years prior to our study.

19

The influence of the soya isoflavones received pre- and postnatally on the mineral metabolism and the function of the male reproductive system in rats

51%

Czuprynska K. , Marchlewicz M. , Baranowska-Bosiacka I. , Gutowska I. , Nocen I. , Wiszniewska B. , Chlubek D.

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nr Supplement 4

20

Testis morphology in rats chronically treated with letrozole, an aromatase inhibitor

51%

Kondarewicz A. , Kolasa A. , Zawislak B. , Baranowska-Bosiacka I. , Marchlewicz M. , Wenda-Rozewicka L. , Wiszniewska B.

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nr 4