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Bacillus anthracis. Potencjalny kandydat na bron biologiczna?

100%

Futoma-Koloch B. , Bugla-Ploskonska G.

nr 01

10-12

Lizozym - bakteriobojczy enzym o szerokim spektrum zastosowan

80%

Bugla-Ploskonska G. , Wojtowicz I. , Futoma-Koloch B.

Ekonatura

2008

nr 07

6-8

Use of zwitterionic type of detergent in isolation of Escherichia coli O56 outer membrane proteins improves their two-dimensional electrophoresis [2-DE]

80%

Bugla-Ploskonska G. , Futoma-Koloch B. , Skwara A. , Doroszkiewicz W.

nr 3

205-209

Escherichia coli O56 were originally isolated from infected humans. Here it is reported that using the zwitterionic detergent (Zwittergent Z 3-14®) to isolate outer membrane proteins (OMPs) from Escherichia coli O56 is suitable for their separation by two-dimensional electrophoresis (2-DE) using pH 3-10 immobilized pH gradient IPG strips (BIO-RAD).

Modyfikacje struktur komórkowych mikroorganizmów wywoływane działaniem biocydów

70%

Krzyzewska E. , Ksiazczyk M. , Kedziora A. , Futoma-Koloch B. , Bugala-Ploskonska G.

nr 4

Selection and electrophoretic characterization of Salmonella enterica subsp. enterica biocide variants resistant to antibiotics

51%

Futoma-Koloch B. , Ksiazczyk M. , Korzekwa K. , Migdal I. , Pawlak A. , Jankowska M. , Kedziora A. , Dorotkiewicz-Jach A. , Bugla-Ploskonska C.

nr 4

The proposed research outlines a serious common concern of Salmonella resistance to antimicrobials following prolonged exposure to the disinfectants (biocides). These phenotypes of bacteria could potentially result in hard to treat infections. Typical for avian sources, biocide sensitive S. enterica subsp. enterica serovars: Typhimurium, Enteritidis, Virchow and Zanzibar and their isogenic biocide-tolerant variants were studied in order to investigate bacteriostatic effect of two commercially available biocide formulations: potassium peroxymonosulfate (P) and dodecylamine based structure (triamine, D). We found that cultivating of the bacteria in the medium supplemented with a blend containing P did not influence their antibiotic susceptibility pattern. In contrast, tolerance of bacteria to D compound resulted in resistance to co-trimoxazole, cefotaxime and ciprofloxacin of which two cefotaxime and ciprofloxacin are used commonly for the treatment of invasive Salmonella infections in humans. The dependency between OMP patterns and the level of Salmonella survival in media containing the biocides was observed merely in serovar Typhimurium. In conclusion, these results suggest that Salmonella strains challenged by prolonged treatment with the disinfectants become resistant to antibiotics, however it depends on Salmonella serovar and the chemical used. This paper also highlights the loop-mediated isothermal amplification (LAMP) as a technique that offers great benefits to microbiological detecting of Salmonella species in the samples.

Human complement activation by smooth and rough Proteus mirabilis lipopolysaccharides

51%

Kaca W. , Arabski M. , Fudala R. , Holmstrom E. , Sjoholm A. , Weintraub A. , Futoma-Koloch B. , Bugla-Ploskonska G. , Doroszkiewicz W.

tom 57

nr 5

383-391