A novel approach is employed to a general solution for one-dimensional steady-state thermal and mechanical stresses in a hollow thick cylinder made of a functionally graded material (FGM). The temperature distribution is assumed to be a function of radius, with general thermal and mechanical boundary conditions on the inside and outside surfaces of the cylinder. The material properties, except Poisson’s ratio, are assumed to be exponentially-varying through the thickness. Forcing functions applied to the inner boundary are internal pressures which may be in form of steps. These conditions result in governing differential equations with variable coefficients. Analytical solutions to such equations cannot be obtained except for certain simple grading functions and pressures. Numerical approaches must be adopted to solve the problem in hand. The novelty of the present study lies in the fact that the Complementary Functions Method (CFM) is employed in the analysis. The Complementary Functions method (CFM) will be infused into the analysis to convert the problem into an initial-value problem which can be solved accurately. Benchmark solutions available in the literature are used to validate the results and to observe the convergence of the numerical solutions. The solution procedure is well-structured, simple and efficient and it can be readily applied to cylinders. It is also well suited for problems in which mechanical properties are graded.
The purpose of this study was to determine the diagnostic importance of coagulation parameters in cattle with natural theileriosis. Nine Holstein cross-breed cattle with theileriosis as infected group and 6 healthy Holstein cattle as control group were used in the present study. Mean fibrinogen level, thrombin time (TT), activated partial thromboplastin time (aPTT) and prothrombin time (PT) were not statistically different when control and infected groups compared, except for the D-dimer concentration. Quantitative D-dimer concentrations were determined by immune-turbidimetric assay. D-dimer values increased significantly (p<0.05) in infected group (631.55 ± 74.41 μg/L) compared to control group (370.00 ± 59.94 μg/L). D-dimer sensitivity and specificity were also determined at cut-off concentrations (372 μg/L). Sensitivity and specificity of D-dimer values were determined to be 88.89% and 83.33%, respectively. D-dimer is thought to be important indicator in the evaluation of the prognosis in theileriosis cases. Analysis of D-dimer values before and after treatment in controlled case studies were suggested in future studies to enlighten the issue.
The aim of the study was to investigate the importance of ADA serum and its isoenzyme activity in diagnosing white muscle disease in lambs. The animal material used in the study was forty seven Akkaraman lambs - twenty seven of which had clinical signs of white muscle disease (white muscle disease group) and twenty healthy lambs (control group). Blood samples were taken and Se levels, CK, LDH, AST, ADA and ADA izoenzyme activity were determined. Following this, the animals in the white muscle disease group received 1 mg sodium selenit + 60 mg vitamin E intramuscularly as a single dose. Fourteen days following sodyum selenit + vitamin E application blood samples were again taken and the same analysis repeated. Apart from ADA2 activity, other enzyme activities were significantly high (p<0.001), and serum Se concentrations were significantly low (p<0.001) in animals of the white muscle disease group compared to the control group. When the parameters obtained from the white muscle disease group were compared before and after treatment it was indicated that all enzyme parameters decreased significantly (p<0.001) after treatment. On the other hand, serum Se concentration increased (p<0.01) after treatment in the diseased group. The results confirm that determining ADA serum and its isoenzymes, together with CK, LDH and AST values seems to be useful in diagnosing white muscle disease.
An acquired megaoesophagus in a calf has been described. The diagnosis of megaoesophagus was made based on clinical and laboratory examinations, using contrast radiography, and necropsy findings. Atropine sulphate was used to enlighten the relationship between damage in the N. vagus and bradycardia, which developed in the megaoesophagus case.