Wyniki wyszukiwania - Biblioteka Nauki

Nowa wersja platformy, zawierająca wyłącznie zasoby pełnotekstowe, jest już dostępna.
Przejdź na https://bibliotekanauki.pl

Ograniczanie wyników

Znaleziono wyników: 2

Liczba wyników na stronie

Wyniki wyszukiwania

Sortuj według:

Ogranicz wyniki do:

THE MEANING AND IMPORTANCE OF EUROPEAN IDENTITY AND ITS RELATIONSHIP TO REGIONAL AND NATIONAL IDENTITIES IN SPAIN: SOME CONTRIBUTING FACTORS TO THE DEVELOPMENT OF EUROPEAN IDENTITY

100%

Grad H. , Ros M. , Garcia-Albacete G. , Rodriguez-Monter M.

Sociológia (Sociology)

2004

tom 36

nr 3

219-236

European, Spanish, and regional identities were studied as part of a wider research survey of youth beliefs and experiences regarding the European Union. The research was conducted in the capital city (Madrid) and the Basque Country (Bilbao). At each location, representative and European-oriented youth samples (N=400 and N=100 each) of 18-24 years (50% female) were gathered. The interviewees were asked about their perception of border countries as included in Europe, and to rate different feasible meanings of the EU, its impact (at personal, regional, and country levels), and different cognitive, affective and evaluative aspects of European, Spanish and regional identities. Regarding European borders, Turkey was the only country most interviewees did not perceive as part of or belonging to Europe. Geography, membership in the EU and, above all, the Euro currency emerged as the most salient features of meaning for Europe (beyond shared values and traditions). The European Union was perceived as having a positive, but small impact for the person, moderate for the region, and greater impact for the country of Spain. The identity patterns were similar in most of their aspects: In Madrid, the Spanish identity was the most important, the importance of regional identity was similar to it, and the identification with Europe was moderate, the least important. In Bilbao, the identification with the Basque Country was the strongest, while Spanish and European identities were related and came out of 'little' importance. Older interviewees presented stronger European identity in the pro-European but weaker in the general sample. Finally, interviewees considered themselves only 'sometimes' as a 'European citizen' with no significant difference by Region, Age or Gender group.These relationships seem to reflect the configuration of different levels of social identity. The hegemony of different nationalist orientations led to a distinct meaning of national identity in each region (Spain in Madrid but the Basque Country in Bilbao). Thus, instead of a continuum of social category inclusiveness (as suggested by Brewer 1991), the results show different breaches between levels of social categories and identities - between Basque and higher levels in Bilbao and between Spanish and higher levels in Madrid. Summing up, the identity level reflecting the dominant national identity seems to function as a basic category distinctively organizing the whole identity configuration.The impact of the European Union was perceived as much stronger for the country (Spain) than for the region and the person. Madrid and pro-European samples perceived stronger impact on the less inclusive categories. Beyond the different identity configurations, these patterns suggest a relationship between the weak perceived impact of the European Union on levels closer to the person and the weak identification with Europe. Finally, though interviewees did not recall learning a lot about the European Union at school, this perception, as well as the experience of visiting other European countries and mastering European languages, was enhanced in the younger and the pro-European sample (and among Bilbao respondents). Thus, personal and social experiences would reinforce the perceived impact of the European Union at the personal level and certainly contribute to reinforce a shared European identity beyond national-regional nuances in the Spanish context.

Identification of serum proteome components associated with progression of non - small cell lung cancer

51%

Pietrowska M. , Jelonek K. , Michalak M. , Ros M. , Rodziewicz P. , Chmielewska K. , Polanski K. , Polanska J. , Godowicz-Klosok A. , Giglok M. , Suwinski R. , Tarnowski R. , Dziadziuszko R. , Rzyman W. , Widlak P.

Acta Biochimica Polonica

2014

tom 61

nr 2

The aim of the present study was to perform comparative analysis of serum from patients with different stages of non-small cell lung cancer (NSCLC) using the three complementary proteomic approaches to identify proteome components associated with the progression of cancer. Serum samples were collected before any treatment from 200 patients with NSCLC, including 103 early stage, 64 locally advanced and 33 metastatic cancer samples, and from 200 donors without malignancy. The low-molecular-weight fraction of serum proteome was MALDI-profiled in all samples. Serum proteins were characterized using 2D-PAGE and LC-MS/MS approaches in a representative group of 30 donors. Several significant differences were detected between serum samples collected from patients with early stage cancer and patients with locally advanced cancer, as well as between patients with metastatic cancer and patients with local disease. Of note, serum components discriminating samples from early stage cancer and healthy persons were also detected. In general, about 70 differentiating serum proteins were identified, including inflammatory and acute phase proteins already reported to be associated with the progression of lung cancer (serum amyloid A or haptoglobin). Several differentiating proteins, including apolipoprotein H or apolipoprotein A1, were not previously associated with NSCLC. No significant differences in patterns of serum proteome components were detected between patients with adenocarcinoma and squamous cell carcinoma. In conclusion, we identified the biomarker candidates with potential importance for molecular proteomic staging of NSCLC. Additionally, several serum proteome components revealed their potential applicability in early detection of the lung cancer.